About Enhancer
| Enhancer ID: | E_04472 |
| Species: | Homo sapiens |
| Position : | chr7:117342000-117345000   |
| Year: | 2016 |
| Title: | Analysis of long-range interactions in primary human cells identifies cooperative CFTR regulatory elements. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | cutaneous melanoma |
| PMID: | 26615198 |
| MONDO: | MONDO:0005012 |
| Tissue: | zone of skin |
| Tissue Ontology ID: | UBERON:0000014 |
| Cell Source: | COLO 829 |
| CVCL ID: | CVCL_1137 |
| Cell Type: | melanoma cell |
| Experiment Type: | Chromatin interaction assay |
| High Throughput Method: | Hi-C; ChIP-seq |
| Low Throughput Method: | Luciferase Reporter Assay |
About Target Gene
| Target gene : | CFTR |
About TF
| TF name : | CTCF |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CTCF | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| CTCF | TGF_beta_Receptor | netpath | 220 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer