Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04476
Species: Homo sapiens
Position : chr14:22420000-22422000
Year: 2002
Title: Disruption of the RanBP17/Hox11L2 region by recombination with the TCRdelta locus in acute lymphoblastic leukemias with t(5;14)(q34;q11).
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: B-cell acute lymphoblastic leukemia
PMID:  12399963
MONDO: MONDO:0004947
Tissue: blood
Tissue Ontology ID: UBERON:0000178
Cell Source: Leukemic B Lymphoblasts
Cell Type: B-lymphoblast
Cell Ontology ID: CL:0017006
Experiment Type: Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay
Low Throughput Method: Southern Blot, PCR, Sequencing, FISH
About Target Gene
Target gene : TLX3
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_04483 chr14:22420000-22422000 thymus T lymphocyte progenitor NA
E_04499 chr14:22420000-22422000 zone of skin keratinocyte NA
Expression of Target Genes for the Enhancer