About Enhancer
| Enhancer ID: | E_04477 |
| Species: | Homo sapiens |
| Position : | chr7:117074000-117077000   |
| Year: | 2016 |
| Title: | Analysis of long-range interactions in primary human cells identifies cooperative CFTR regulatory elements. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 26615198 |
| Tissue: | nasal cavity epithelium |
| Tissue Ontology ID: | UBERON:0005384 |
| Cell Source: | HNECs |
| Cell Type: | nasal epithelial cell |
| Experiment Type: | Chromatin interaction assay |
| High Throughput Method: | Hi-C; ChIP-seq |
| Low Throughput Method: | Luciferase Reporter Assay |
About Target Gene
| Target gene : | CFTR |
About TF
| TF name : | SMARCC1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| SMARCC1 | AndrogenReceptor | netpath | 167 |
| SMARCC1 | Glucocorticoid receptor regulatory network | pid | 85 |
| SMARCC1 | Regulation of Androgen receptor activity | pid | 54 |
| SMARCC1 | RMTs methylate histone arginines | reactome | 75 |
| SMARCC1 | TNFalpha | netpath | 274 |
| SMARCC1 | Wnt signaling pathway | panther | 250 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
9 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00034 | chr7:117075400-117076000 | bronchus | bronchial epithelial cell | NA |
| E_00035 | chr7:117075400-117076000 | pleural effusion | epithelial cell | NA |
| E_00036 | chr7:117075400-117076000 | bronchus | bronchial epithelial cell | NA |
| E_00037 | chr7:117075400-117076000 | pleural effusion | epithelial cell | NA |
| E_00038 | chr7:117075400-117076000 | bronchus | bronchial epithelial cell | NA |
| E_00039 | chr7:117075400-117076000 | pleural effusion | epithelial cell | NA |
| E_03835 | chr7:117075400-117076000 | bronchus | bronchial epithelial cell | NA |
| E_03882 | chr7:117075514-117075933 | NA | NA | NA |
| E_03883 | chr7:117075514-117075933 | NA | NA | NA |
Expression of Target Genes for the Enhancer