Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04511
Species: Homo sapiens
Position : chr11:5278952-5279402
Year: 2017
Title: Multiplexed Engineering and Analysis of Combinatorial Enhancer Activity in Single Cells.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
PMID:  28416141
Tissue: bone marrow
Tissue Ontology ID: UBERON:0002371
Cell Source: K-562
CVCL ID: CVCL_0004
Cell Type: malignant cell
Cell Ontology ID: CL:0001064
Experiment Type: CRISPRi-based single-cell enhancer perturbation
High Throughput Method: Drop-seq single-cell RNA-seq, CRISPR barcoding
Low Throughput Method: qRT-PCR, and ChIP-qPCR
About Target Gene
Target gene : HBG2
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 4 found
Enhancer ID Position Tissue Cell Disease
E_02356 chr11:5222500-5323700 blood erythroid cell NA
E_02363 chr11:5222500-5323700 blood erythroid cell NA
E_02364 chr11:5222500-5323700 blood erythroid cell NA
E_02365 chr11:5222500-5323700 blood erythroid cell NA
Expression of Target Genes for the Enhancer