Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04516
Species: Mus musculus
Position : chr6:70725951-70726429
Year: 1992
Title: Immunoglobulin kappa gene enhancers synergistically activate gene expression but independently determine chromatin structure.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  1429727
Cell Source: S194/5.XXO.BU.1
CVCL ID: CVCL_4696
Cell Type: plasma cell
Cell Ontology ID: CL:0000786
Experiment Type: Enhancer activity assay; Functional perturbation assay; Chromatin accessibility assay; Chromatin structure assay; Endogenous enhancer perturbation; In vivo functional validation
Low Throughput Method: Enhancer deletion constructs; transient transfection expression assay; stable transfection/integration assay; DNase I hypersensitivity assay; Northern blot; Southern blot; restriction mapping; Mouse genetic deletion/knock-in
About Target Gene
Target gene : Igk
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 1 found
Enhancer ID Position Tissue Cell Disease
E_05325 chr6:70725576-70726090 NA NA NA
Expression of Target Genes for the Enhancer