About Enhancer
| Enhancer ID: | E_04518 |
| Species: | Homo sapiens |
| Position : | chr11:5258353-5258721   |
| Year: | 2017 |
| Title: | Multiplexed Engineering and Analysis of Combinatorial Enhancer Activity in Single Cells. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 28416141 |
| Tissue: | pleural effusion |
| Tissue Ontology ID: | UBERON:0000175 |
| Cell Source: | K-562 |
| CVCL ID: | CVCL_0004 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | CRISPRi-based single-cell endogenous enhancer perturbation |
| High Throughput Method: | Drop-seq single-cell RNA-seq; sgRNA barcode sequencing |
| Low Throughput Method: | Independent RT-qPCR |
About Target Gene
| Target gene : | HBG1 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
5 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02356 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_02363 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_02364 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_02365 | chr11:5222500-5323700 | blood | erythroid cell | NA |
| E_04971 | chr11:5255062-5258441 | blood / hematopoietic system | NA | Erythrocytic Leukemia |
Expression of Target Genes for the Enhancer