About Enhancer
| Enhancer ID: | E_04519 |
| Species: | Homo sapiens |
| Position : | chr6:37151046-37151259   |
| Year: | 2017 |
| Title: | Multiplexed Engineering and Analysis of Combinatorial Enhancer Activity in Single Cells. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 28416141 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | K-562 |
| CVCL ID: | CVCL_0004 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Multiplex endogenous enhancer perturbation with single-cell transcriptomic readout |
| High Throughput Method: | Mosaic-seq pooled dCas9-KRAB CRISPRi; single-cell RNA-seq; DNase/ChIP integration |
| Low Throughput Method: | targeted guide validation; qRT-PCR; endogenous CRISPRi validation |
About Target Gene
| Target gene : | PIM1 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer