About Enhancer
| Enhancer ID: | E_04541 |
| Species: | Mus musculus |
| Position : | chr5:28875380-28876679   |
| Year: | 2022 |
| Title: | Cohesin is required for long-range enhancer action at the Shh locus. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 36097291 |
| Tissue: | diencephalon |
| Tissue Ontology ID: | UBERON:0001894 |
| Cell Source: | ES-E14 |
| CVCL ID: | CVCL_C320 |
| Cell Type: | embryonic stem cell |
| Cell Ontology ID: | CL:0002322 |
| Experiment Type: | Synthetic enhancer activation assay; Cohesin/CTCF functional perturbation assay; Chromatin conformation analysis |
| High Throughput Method: | Hi-C data reanalysis; virtual 4C |
| Low Throughput Method: | TALE-VP64 synthetic enhancer activation; auxin-inducible SCC1/RAD21 degradation; auxin-inducible CTCF degradation; RNA FISH; DNA FISH; immunofluorescence; flow cytometry |
About Target Gene
| Target gene : | Shh |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer