About Enhancer
| Enhancer ID: | E_04548 |
| Species: | Homo sapiens |
| Position : | chr8:128600697-128601159   |
| Year: | 2009 |
| Title: | Functional enhancers at the gene-poor 8q24 cancer-linked locus. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | prostate cancer |
| PMID: | 19680443 |
| MONDO: | MONDO:0008315 |
| Tissue: | uterine cervix |
| Tissue Ontology ID: | UBERON:0000002 |
| Cell Source: | HeLa |
| CVCL ID: | CVCL_0030 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Enhancer activity assay, TF binding assay; Enhancer activity assay; Disease-variant functional analysis |
| High Throughput Method: | ChIP-chip; GWAS |
| Low Throughput Method: | Luciferase Reporter Assay, ChIP-RT-qPCR, EMSA; Reporter assay |
About Target Gene
| Target gene : | MYC |
About TF
| TF name : | FOXA1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| FOXA1 | AndrogenReceptor | netpath | 167 |
| FOXA1 | Direct p53 effectors | pid | 141 |
| FOXA1 | FOXA1 transcription factor network | pid | 45 |
| FOXA1 | FOXA2 and FOXA3 transcription factor networks | pid | 45 |
| FOXA1 | Hs_Endoderm_Differentiation_WP2853_88152 | wikipathways | 62 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer