About Enhancer
| Enhancer ID: | E_04563 |
| Species: | Homo sapiens |
| Position : | chr5:110175120-110177136   |
| Year: | 2016 |
| Title: | Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Heart Failure |
| PMID: | 27149122 |
| Tissue: | heart |
| Tissue Ontology ID: | UBERON:0000948 |
| Cell Source: | Blood |
| Experiment Type: | Enhancer activity assay; TF-binding/chromatin assay; Genetic-variant functional analysis; Disease-associated enhancer analysis |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP; RT-qPCR/qPCR; RNAi/siRNA/shRNA |
About Target Gene
| Target gene : | TSLP |
About TF
| TF name : | NHLH1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04580 | chr5:110175800-110176600 | heart | NA | Heart Failure |
Expression of Target Genes for the Enhancer