About Enhancer
| Enhancer ID: | E_04589 |
| Species: | Homo sapiens |
| Position : | chrX:135959959-135963959   |
| Year: | 2022 |
| Title: | Duplications disrupt chromatin architecture and rewire GPR101-enhancer communication in X-linked acrogigantism. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | X-linked acrogigantism |
| PMID: | 35202564 |
| MONDO: | MONDO:0018105 |
| Tissue: | pituitary gland |
| Tissue Ontology ID: | UBERON:0000007 |
| Cell Source: | GH3 |
| CVCL ID: | CVCL_0273 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Enhancer activity assay; Chromatin interaction assay |
| High Throughput Method: | 4C-seq; H3K27ac regulatory annotation; Hi-C; 4C |
| Low Throughput Method: | Luciferase reporter assay |
About Target Gene
| Target gene : | GPR101 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04671 | chrX:135959959-135963959 | blood | peripheral blood mononuclear cell | NA |
Expression of Target Genes for the Enhancer