Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04622
Species: Homo sapiens
Position : chr8:128173203-128174158
Year: 2010
Title: 8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: prostate cancer
PMID:  20453196
MONDO: MONDO:0008315
Tissue: prostate gland
Tissue Ontology ID: UBERON:0002367
Cell Source: LNCaP
CVCL ID: CVCL_0395
Cell Type: malignant cell
Cell Ontology ID: CL:0001064
Experiment Type: Enhancer activity assay, Chromatin interaction assay, TF binding assay
Low Throughput Method: ChIP-RT-qPCR, 3C
About Target Gene
Target gene : MYC
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 7 found
Enhancer ID Position Tissue Cell Disease
E_03270 chr8:128000000-128300000 colon malignant cell colorectal cancer
E_01136 chr8:128130000-128300000 lymphoid tissue B cell mantle cell lymphoma
E_01137 chr8:128130000-128300000 lymphoid tissue B cell mantle cell lymphoma
E_01138 chr8:128130000-128300000 lymphoid tissue B cell mantle cell lymphoma
E_01139 chr8:128130000-128300000 lymphoid tissue B cell mantle cell lymphoma
E_01140 chr8:128130000-128300000 lymphoid tissue B cell mantle cell lymphoma
E_01141 chr8:128130000-128300000 lymphoid tissue B cell mantle cell lymphoma
Expression of Target Genes for the Enhancer