About Enhancer
| Enhancer ID: | E_04635 |
| Species: | Homo sapiens |
| Position : | chr2:239866844-239871938   |
| Year: | 2025 |
| Title: | Genomic Locus Tagged by Lung Function GWAS SNV rs12477314 (2q37.3) Acts as a Regulatory Region for a Systemic Inflammatory Phenotype. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | chronic obstructive pulmonary disease |
| PMID: | 40512334 |
| MONDO: | MONDO:0005002 |
| Tissue: | lung |
| Tissue Ontology ID: | UBERON:0002048 |
| Cell Source: | NCI-H460 |
| CVCL ID: | CVCL_0459 |
| Cell Type: | large cell lung carcinoma epithelial cell |
| Experiment Type: | Enhancer activity assay; Functional perturbation assay |
| High Throughput Method: | RNA-seq; DNA methylation profiling |
| Low Throughput Method: | CRISPR/Cas9 deletion; Sanger sequencing; RT-qPCR; CRISPR-Cas9 |
About Target Gene
| Target gene : | CXCL2 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer