About Enhancer
| Enhancer ID: | E_04650 |
| Species: | Mus musculus |
| Position : | chr6:71321750-71323696   |
| Year: | 2016 |
| Title: | Dynamic recruitment of Ets1 to both nucleosome-occupied and -depleted enhancer regions mediates a transcriptional program switch during early T-cell differentiation. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 26673693 |
| Cell Source: | P5424 |
| Experiment Type: | TF-binding/chromatin assay; Chromatin interaction assay |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | ChIP-qPCR/ChIP; RT-qPCR/qPCR; Western blot |
About Target Gene
| Target gene : | Cd8b1 |
About TF
| TF name : | Runx1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Runx1 | AndrogenReceptor | netpath | 167 |
| Runx1 | Organic cation transport | reactome | 9 |
| Runx1 | RANKL | netpath | 84 |
| Runx1 | Regulation of nuclear SMAD2/3 signaling | pid | 82 |
| Runx1 | TGF_beta_Receptor | netpath | 220 |
| Runx1 | Validated transcriptional targets of deltaNp63 isoforms | pid | 47 |
| Runx1 | Pathways in cancer | kegg | 321 |
| Runx1 | Chronic myeloid leukemia | kegg | 69 |
| Runx1 | Acute myeloid leukemia | kegg | 53 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer