Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04686
Species: Mus musculus
Position : chr1:133347808-133348049
Year: 2014
Title: A mouse renin distal enhancer is essential for blood pressure homeostasis in BAC-rescued renin-null mutant mice.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  24734888
Tissue: kidney
Tissue Ontology ID: UBERON:0002113
Cell Source: Kidney
Experiment Type: In vivo functional validation
Low Throughput Method: Transgenic/LacZ assay
About Target Gene
Target gene : Ren1
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 2 found
Enhancer ID Position Tissue Cell Disease
E_03824 chr1:133347574-133364574 NA NA Hypertension
E_04666 chr1:133347808-133348049 kidney kidney granular cell NA
Expression of Target Genes for the Enhancer