About Enhancer
| Enhancer ID: | E_04725 |
| Species: | Homo sapiens |
| Position : | chr14:56793806-56795906   |
| Year: | 2025 |
| Title: | Targeting TET3 suppresses group 3 medulloblastoma stemness and progression via impairing hypomethylation of Otx2 super-enhancer. |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 41338221 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Lymphoblastoid |
| Cell Type: | lymphoblastoid cell |
| Experiment Type: | Super-enhancer activity assay, Functional perturbation assay |
| High Throughput Method: | WGBS; CUT&Tag; DNA methylation profiling |
| Low Throughput Method: | Luciferase reporter assay; ChIP-RT-qPCR; RT-RT-qPCR |
About Target Gene
| Target gene : | OTX2 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer