About Enhancer
| Enhancer ID: | E_04734 |
| Species: | Mus musculus |
| Position : | chr6:98336842-98365566   |
| Year: | 2019 |
| Title: | Promoter-Enhancer Communication Occurs Primarily within Insulated Neighborhoods. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 30527662 |
| Cell Source: | Mouse Embryonic Stem Cell |
| Experiment Type: | TF-binding/chromatin assay; Chromatin interaction assay |
| High Throughput Method: | ChIP-seq; Hi-C; ChIA-PET |
| Low Throughput Method: | ChIP-qPCR/ChIP; 4C; Western blot; RNAi/siRNA/shRNA |
About Target Gene
| Target gene : | Mitf |
About TF
| TF name : | Med1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Med1 | Activation of gene expression by SREBF (SREBP) | reactome | 42 |
| Med1 | BMAL1:CLOCK,NPAS2 activates circadian gene expression | reactome | 42 |
| Med1 | Circadian Clock | reactome | 49 |
| Med1 | Coregulation of Androgen receptor activity | pid | 61 |
| Med1 | Generic Transcription Pathway | reactome | 358 |
| Med1 | Hedgehog | netpath | 39 |
| Med1 | Nuclear Receptor transcription pathway | reactome | 51 |
| Med1 | PPARA activates gene expression | reactome | 113 |
| Med1 | Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | reactome | 20 |
| Med1 | RORA activates gene expression | reactome | 27 |
| Med1 | RXR and RAR heterodimerization with other nuclear receptor | pid | 26 |
| Med1 | Transcriptional activation of mitochondrial biogenesis | reactome | 43 |
| Med1 | Transcriptional regulation of white adipocyte differentiation | reactome | 79 |
| Med1 | Validated nuclear estrogen receptor alpha network | pid | 65 |
| Med1 | YAP1- and WWTR1 (TAZ)-stimulated gene expression | reactome | 29 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04733 | chr6:98336842-98365566 | NA | NA | NA |
Expression of Target Genes for the Enhancer