About Enhancer
| Enhancer ID: | E_04739 |
| Species: | Homo sapiens |
| Position : | chr10:64737032-64737909   |
| Year: | 2015 |
| Title: | Chimeric EWSR1-FLI1 regulates the Ewing sarcoma susceptibility gene EGR2 via a GGAA microsatellite. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Ewing Sarcoma |
| PMID: | 26214589 |
| MONDO: | MONDO:0012817 |
| Cell Source: | Mouse Embryonic Stem Cell |
| Experiment Type: | Enhancer activity assay; TF-binding/chromatin assay; Disease-associated enhancer analysis |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP; RT-qPCR/qPCR |
About Target Gene
| Target gene : | EGR2 |
About TF
| TF name : | EWSR1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| EWSR1 | BARD1 signaling events | pid | 29 |
| EWSR1 | TGF_beta_Receptor | netpath | 220 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04735 | chr10:64737032-64737909 | bone tissue | Ewing sarcoma cell | Ewing sarcoma |
Expression of Target Genes for the Enhancer