About Enhancer
| Enhancer ID: | E_04741 |
| Species: | Homo sapiens |
| Position : | chr1:24601612-24626812   |
| Year: | 2017 |
| Title: | BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Breast Cancer |
| PMID: | 27980063 |
| MONDO: | MONDO:0007254 |
| Tissue: | blood / hematopoietic system |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Raji lymphoblastic B cells |
| Experiment Type: | Enhancer activity assay; TF-binding/chromatin assay; Genetic-variant functional analysis; Disease-associated enhancer analysis |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP; Western blot |
About Target Gene
| Target gene : | GRHL3 |
About TF
| TF name : | GRHL3 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer