Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04745
Species: Homo sapiens
Position : chr1:24589812-24645812
Year: 2017
Title: BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: Breast Cancer
PMID:  27980063
MONDO: MONDO:0007254
Tissue: breast
Tissue Ontology ID: UBERON:0000310
Cell Source: Mammary Epithelial Cell MCF10A and MCF12A
Experiment Type: TF-binding/chromatin assay; Disease-associated enhancer analysis
Low Throughput Method: ChIP-qPCR/ChIP; RT-qPCR/qPCR
About Target Gene
Target gene : GRHL3
About TF
TF name : BRD4
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 3 found
Enhancer ID Position Tissue Cell Disease
E_04749 chr1:24589812-24645812 breast NA Breast Cancer
E_04741 chr1:24601612-24626812 blood / hematopoietic system NA Breast Cancer
E_04743 chr1:24601612-24626812 blood / hematopoietic system NA Breast Cancer
Expression of Target Genes for the Enhancer