About Enhancer
| Enhancer ID: | E_04747 |
| Species: | Homo sapiens |
| Position : | chr3:189109942-189219942   |
| Year: | 2017 |
| Title: | BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Breast Cancer |
| PMID: | 27980063 |
| MONDO: | MONDO:0007254 |
| Tissue: | breast |
| Tissue Ontology ID: | UBERON:0000310 |
| Cell Source: | Mammary Epithelial Cell MCF10A and MCF12A |
| Experiment Type: | TF-binding/chromatin assay; Disease-associated enhancer analysis |
| Low Throughput Method: | ChIP-qPCR/ChIP; RT-qPCR/qPCR |
About Target Gene
| Target gene : | TP63 |
About TF
| TF name : | BRD4 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
4 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_03941 | chr3:188892648-189232665 | blood / hematopoietic system | B cell | diffuse large B-cell lymphoma |
| E_04751 | chr3:189109942-189219942 | breast | NA | Breast Cancer |
| E_04748 | chr3:189203942-189313942 | breast | NA | Breast Cancer |
| E_04752 | chr3:189203942-189313942 | breast | NA | Breast Cancer |
Expression of Target Genes for the Enhancer