Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04788
Species: Mus musculus
Position : chr2:115794340-115800495
Year: 2014
Title: Polycomb potentiates meis2 activation in midbrain by mediating interaction of the promoter with a tissue-specific enhancer.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  24374176
Cell Source: Embryonic Stem Cell
Experiment Type: TF-binding/chromatin assay; Chromatin interaction assay
High Throughput Method: ChIP-seq
Low Throughput Method: ChIP-qPCR/ChIP; 3C; RT-qPCR/qPCR
About Target Gene
Target gene : Meis2
About TF
TF name : Rnf2
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Rnf2 Oxidative Stress Induced Senescence reactome 120
Rnf2 SUMOylation of DNA damage response and repair proteins reactome 76
Rnf2 SUMOylation of RNA binding proteins reactome 46
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer