About Enhancer
| Enhancer ID: | E_04828 |
| Species: | Homo sapiens |
| Position : | chr1:226065482-226067482   |
| Year: | 2011 |
| Title: | Left-right asymmetry in the level of active Nodal protein produced in the node is translated into left-right asymmetry in the lateral plate of mouse embryos. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 21419113 |
| Cell Source: | Perinodal Cells |
| Experiment Type: | In vivo functional validation |
| Low Throughput Method: | Transgenic/LacZ assay |
About Target Gene
| Target gene : | LEFTY1 |
About TF
| TF name : | FOXH1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| FOXH1 | Regulation of nuclear SMAD2/3 signaling | pid | 82 |
| FOXH1 | Signaling by Activin | reactome | 11 |
| FOXH1 | Signaling by NODAL | reactome | 19 |
| FOXH1 | TGF-beta signaling pathway | panther | 88 |
| FOXH1 | TGF_beta_Receptor | netpath | 220 |
| FOXH1 | Hs_Endoderm_Differentiation_WP2853_88152 | wikipathways | 62 |
| FOXH1 | Hs_Heart_Development_WP1591_90186 | wikipathways | 28 |
| FOXH1 | Hs_Mesodermal_Commitment_Pathway_WP2857_87780 | wikipathways | 47 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer