About Enhancer
| Enhancer ID: | E_04841 |
| Species: | Homo sapiens |
| Position : | chr22:43012000-43013000   |
| Year: | 2015 |
| Title: | Gold nanoparticles induce heme oxygenase-1 expression through Nrf2 activation and Bach1 export in human vascular endothelial cells. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 26445536 |
| Tissue: | umbilical vein |
| Tissue Ontology ID: | UBERON:0002066 |
| Cell Source: | HUVEC-C |
| CVCL ID: | CVCL_2959 |
| Cell Type: | umbilical vein endothelial cell |
| Experiment Type: | Enhancer activity assay |
| High Throughput Method: | ChIP-seq; RNA-seq |
| Low Throughput Method: | Luciferase Reporter Assay; ELISA |
About Target Gene
| Target gene : | HMOX1 |
About TF
| TF name : | NFE2L2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| NFE2L2 | Protein processing in endoplasmic reticulum | kegg | 166 |
| NFE2L2 | Hs_Photodynamic_therapy-induced_unfolded_protein_response_WP3613_89330 | wikipathways | 6 |
| NFE2L2 | Hs_Transcriptional_activation_by_NRF2_WP3_79527 | wikipathways | 6 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer