About Enhancer
| Enhancer ID: | E_04865 |
| Species: | Mus musculus |
| Position : | chr7:97700267-97768731   |
| Year: | 2026 |
| Title: | A regulatory axis for tonotopic MYO7A expression in cochlear hair cells. |
| Genome Build: | mm39 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 41945437 |
| Tissue: | cochlea |
| Tissue Ontology ID: | UBERON:0001842 |
| Cell Source: | EnhancerA-deletion mice |
| Cell Type: | outer hair cell |
| Cell Ontology ID: | CL:0000604 |
| Experiment Type: | Intronic EnhancerA within Myo7a locus; approximately 400-bp endogenous deletion; isoform-specific tonotopic regulation and auditory phenotyping |
| Low Throughput Method: | CRISPR-Cas9 EnhancerA deletion; immunostaining; mechanotransduction electrophysiology; hair-bundle imaging; auditory phenotyping; expression analysis |
About Target Gene
| Target gene : | Myo7a |
About TF
| TF name : | Six2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm39)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04864 | chr7:97700267-97768731 | cochlea | outer hair cell | NA |
Expression of Target Genes for the Enhancer