Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_04885
Species: Homo sapiens
Position : chr8:128816178-128817335
Year: 2014
Title: Targeted repression of AXIN2 and MYC gene expression using designer TALEs.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: colorectal cancer
PMID:  24667606
MONDO: MONDO:0005575
Tissue: colon
Tissue Ontology ID: UBERON:0001155
Cell Source: HEK293FT,FLP-IN T-REX 293 CELLS
Experiment Type: Enhancer activity assay; TF-binding/chromatin assay; Disease-associated enhancer analysis
Low Throughput Method: Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP; RT-qPCR/qPCR
About Target Gene
Target gene : MYC
About TF
TF name : NA
About Regulatory State
Regulatory State : Repressed
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 1 found
Enhancer ID Position Tissue Cell Disease
E_02292 chr8:128750000-129000000 breast malignant cell prostate cancer
Expression of Target Genes for the Enhancer