About Enhancer
| Enhancer ID: | E_04960 |
| Species: | Homo sapiens |
| Position : | chr2:16200000-16205000   |
| Year: | 2022 |
| Title: | ASCL1 regulates super-enhancer-associated miRNAs to define molecular subtypes of small cell lung cancer. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 35789143 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Monocyte |
| Cell Type: | monocyte |
| Cell Ontology ID: | CL:0000576 |
| Experiment Type: | Super enhancer activity assay |
| High Throughput Method: | ChIP-seq; RNA-seq; CUT&Tag |
| Low Throughput Method: | Luciferase Reporter Assay; RT-RT-qPCR |
About Target Gene
| Target gene : | MIR375 |
About TF
| TF name : | ASCL1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| ASCL1 | Notch-mediated HES/HEY network | pid | 48 |
| ASCL1 | Notch | netpath | 76 |
| ASCL1 | Hs_Dopaminergic_Neurogenesis_WP2855_87239 | wikipathways | 19 |
| ASCL1 | Hs_Neural_Crest_Differentiation_WP2064_79263 | wikipathways | 40 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer