About Enhancer
| Enhancer ID: | E_04966 |
| Species: | Mus musculus |
| Position : | chr6:88180138-88180212   |
| Year: | 2012 |
| Title: | Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity. |
| Genome Build: | mm39 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | GATA2 deficiency syndrome |
| PMID: | 22996659 |
| MONDO: | MONDO:0042982 |
| Tissue: | liver |
| Tissue Ontology ID: | UBERON:0002107 |
| Cell Source: | E13.5 fetal liver hematopoietic stem/progenitor cells |
| Cell Type: | hematopoietic stem/progenitor cell |
| Experiment Type: | Functional perturbation assay; Gene expression assay; In vivo developmental assay |
| Low Throughput Method: | Targeted homologous-recombination enhancer deletion; RT-qPCR; flow cytometry; colony-forming assay; immunohistochemistry |
About Target Gene
| Target gene : | Gata2 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm39)
No overlapping enhancers found in mm39 at this locus.
Expression of Target Genes for the Enhancer