About Enhancer
| Enhancer ID: | E_04969 |
| Species: | Homo sapiens |
| Position : | chr11:5198400-5198625   |
| Year: | 2000 |
| Title: | Direct interaction of NF-E2 with hypersensitive site 2 of the beta-globin locus control region in living cells. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 10891470 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | K-562 |
| CVCL ID: | CVCL_0004 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | TF binding assay, Enhancer activity assay; TF binding assay |
| Low Throughput Method: | Luciferase Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR, Western blot; ChIP |
About Target Gene
| Target gene : | HBB |
About TF
| TF name : | NFE2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| NFE2 | Factors involved in megakaryocyte development and platelet production | reactome | 111 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer