About Enhancer
| Enhancer ID: | E_04985 |
| Species: | Homo sapiens |
| Position : | chr18:28988494-35919423   |
| Year: | 2020 |
| Title: | ASXL3 bridges BRD4 to BAP1 complex and governs enhancer activity in small cell lung cancer. |
| Genome Build: | hg19 |
| Enhancer Type: | Super-enhancer |
| Condition: | Disease |
| Disease Name: | small cell lung carcinoma |
| PMID: | 32669118 |
| MONDO: | MONDO:0008433 |
| Tissue: | lung |
| Tissue Ontology ID: | UBERON:0002048 |
| Cell Source: | NCI-H1963 |
| CVCL ID: | CVCL_1510 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay; Chromatin-state profiling |
| High Throughput Method: | ChIP-seq, RNA-seq, ATAC-seq; RNA-seq; ChIP-seq |
| Low Throughput Method: | shRNA Knockdown, qRT-PCR, Western blot; ChIP; Western blot |
About Target Gene
| Target gene : | TCF4 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer