About Enhancer
| Enhancer ID: | E_04990 |
| Species: | Mus musculus |
| Position : | chr16:59471850-59472124   |
| Year: | 2013 |
| Title: | Transcriptional activation of Mina by Sp1/3 factors. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Pulmonary Inflammation |
| PMID: | 24324617 |
| Tissue: | lung |
| Tissue Ontology ID: | UBERON:0002048 |
| Cell Source: | EL4 |
| CVCL ID: | CVCL_0255 |
| Experiment Type: | Enhancer activity assay; TF-binding/chromatin assay; Disease-associated enhancer analysis |
| Low Throughput Method: | Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP; EMSA/gel-shift assay; RT-qPCR/qPCR |
About Target Gene
| Target gene : | Riox2 |
About TF
| TF name : | Sp3 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Sp3 | Leptin | netpath | 98 |
| Sp3 | Regulation of nuclear SMAD2/3 signaling | pid | 82 |
| Sp3 | Regulation of Telomerase | pid | 70 |
| Sp3 | SUMOylation of transcription factors | reactome | 14 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04989 | chr16:59471850-59472124 | lung | NA | Pulmonary Inflammation |
Expression of Target Genes for the Enhancer