About Enhancer
| Enhancer ID: | E_05019 |
| Species: | Homo sapiens |
| Position : | chr2:218000000-218700000   |
| Year: | 2023 |
| Title: | Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas. |
| Genome Build: | hg38 |
| Enhancer Type: | Super-enhancer |
| Condition: | Normal |
| PMID: | 37805627 |
| Tissue: | breast |
| Tissue Ontology ID: | UBERON:0000310 |
| Cell Source: | Breast Adipose Fibroblasts (BAFs) |
| Cell Type: | fibroblast |
| Cell Ontology ID: | CL:0000057 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay |
| High Throughput Method: | HiChIP, H3K27ac ChIP-seq, RNA-seq, WGS, WES |
| Low Throughput Method: | Immunofluorescence, Sanger Sequencing |
About Target Gene
| Target gene : | IHH |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
6 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_03011 | chr2:217799791-218033982 | blood | B-lymphoblast | B-cell acute lymphoblastic leukemia |
| E_03036 | chr2:217799791-218033982 | blood | B-lymphoblast | B-cell acute lymphoblastic leukemia |
| E_03037 | chr2:217799791-218033982 | blood | B-lymphoblast | B-cell acute lymphoblastic leukemia |
| E_03038 | chr2:217799791-218033982 | blood | B-lymphoblast | B-cell acute lymphoblastic leukemia |
| E_03039 | chr2:217799791-218033982 | blood | B-lymphoblast | B-cell acute lymphoblastic leukemia |
| E_03040 | chr2:217799791-218033982 | blood | B-lymphoblast | B-cell acute lymphoblastic leukemia |
Expression of Target Genes for the Enhancer