About Enhancer
| Enhancer ID: | E_05179 |
| Species: | Homo sapiens |
| Position : | chr1:183149939-183150336   |
| Year: | 2017 |
| Title: | Regulation of Laminin 污2 Expression by CDX2 in Colonic Epithelial Cells Is Impaired During Active Inflammation. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 27333824 |
| Tissue: | small intestine |
| Tissue Ontology ID: | UBERON:0002108 |
| Cell Source: | Intestinal Epithelial Cell |
| Experiment Type: | Enhancer activity assay; TF-binding/chromatin assay |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP |
About Target Gene
| Target gene : | LAMC2 |
About TF
| TF name : | CDX2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CDX2 | POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | reactome | 10 |
| CDX2 | Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | reactome | 20 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
4 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_03365 | chr1:183149939-183150336 | colon | intestinal epithelial cell | NA |
| E_03366 | chr1:183149939-183150336 | colon | intestinal epithelial cell | NA |
| E_03367 | chr1:183149939-183150336 | colon | intestinal epithelial cell | NA |
| E_05173 | chr1:183149939-183150336 | colon | colon epithelial cell | NA |
Expression of Target Genes for the Enhancer