Gene Overview
| Target Gene: | Adra1a |
| NCBI Official Symbol: | Adra1a |
| Entrez ID: | 11549 |
| Ensembl ID: | ENSMUSG00000045875 |
| Gene Full Name: | adrenergic receptor, alpha 1a |
| Strand: | + |
| Gene Locus: | 14|14 D1 |
| External Links: |
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Adra1a Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Adra1a
T(co)Fs
that Repress Adra1a
The Intensity of the Gene Regulated by T(co)Fs:
Adra1a-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Adra1a | Bcl11a | knockout | Bone_marrow | Bone marrow erythoid progenitors | 0.603431 | -0.728739 | 0.14764502134546 | 0.537886767925872 | DataSet_11_013 |
| Adra1a | Bcl6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.585774 | -0.771584 | 0.0827419831498832 | 0.443186255898313 | DataSet_11_014 |
| Adra1a | Cebpb | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.56416 | -0.825825 | - | - | DataSet_11_021 |
| Adra1a | Cebpe | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.54629 | -0.87226 | - | - | DataSet_11_023 |
| Adra1a | E2f4 | knockout | Brain | Forebrain | 2.60557 | 1.3816 | - | - | DataSet_11_034 |
| Adra1a | Elf5 | knockout | Mammary_gland | Mammary gland | 0.529665 | -0.916849 | 0.205131600731954 | 0.491581112741935 | DataSet_11_035 |
| Adra1a | Foxp1 | knockout | Eye | Lens | 0.149425 | -2.7425 | - | - | DataSet_11_044 |
| Adra1a | Gata2 | knockout | Kidney | renal collecting duct cells | 1.6564 | 0.728051 | - | - | DataSet_11_047 |
| Adra1a | Gata3 | siRNA | Peripheral_blood | CD4+ T helper (Th) cells | 0.543303 | -0.880171 | 0.179431291780313 | 0.987135756219234 | DataSet_11_048 |
| Adra1a | Gata4 | knockout | Intestine | Jejunum | 0.439226 | -1.18696 | 0.0407605409665605 | 0.473892505985228 | DataSet_11_049 |
| Adra1a | Gfi1 | knockout | Cord_Blood | T-cells | 0.477918 | -1.06517 | 0.325674468215184 | 0.702501712057016 | DataSet_11_053 |
| Adra1a | Junb | shRNA | Tibialis_anterior_muscle | Tibialis anterior muscle | 1.71338 | 0.776846 | 0.230752804376573 | 0.521565035708682 | DataSet_11_065 |
| Adra1a | Mafg | knockout | Embryo | Whole embryo | 0.625857 | -0.676094 | 0.377885194805431 | 1 | DataSet_11_073 |
| Adra1a | Mbd1 | siRNA | Adipose_tissue | 3T3-L1 cells | 2.24 | 1.1635 | - | - | DataSet_11_074 |
| Adra1a | Meis1 | knockout | Hematopoietic | KSL hematopoietic cells | 1.51625 | 0.600503 | 0.456310318379233 | 0.995635220774426 | DataSet_11_081 |
| Adra1a | Nr2f2 | knockout | Ovary | E14.5 Ovary | 5.89177 | 2.5587 | 0.00144271212411027 | 0.475060234221242 | DataSet_11_094 |
| Adra1a | Nr2f2 | knockout | Ovary | E16.5 Ovary | 0.362679 | -1.46324 | 0.00909568536517455 | 0.254250148462379 | DataSet_11_095 |
| Adra1a | Otx2 | knockout | Eye | Retina | 0.655379 | -0.6096 | 0.780784505629965 | 0.999923528647439 | DataSet_11_097 |
| Adra1a | Prox1 | knockout | Liver | Liver | 1.88803 | 0.916884 | - | - | DataSet_11_109 |
| Adra1a | Runx1 | knockout | Bone_marrow | KSL cells | 0.524575 | -0.930779 | 0.314711784723947 | 0.964077388243163 | DataSet_11_115 |
| Adra1a | Runx1 | knockout | Mammary_gland | Luminal epithelial cells | 0.482103 | -1.05259 | 0.195318634346607 | 0.999784944667092 | DataSet_11_117 |
| Adra1a | Sox11 | knockout | Eye | Retina | 0.286765 | -1.80206 | - | - | DataSet_11_137 |
| Adra1a | Sox11 | knockout | Brain | Cortex | 0.602322 | -0.731392 | - | - | DataSet_11_138 |
| Adra1a | Spdef | knockout | Colon | Colon | 3.11877 | 1.64098 | 0.0698873345524219 | 0.997507742354799 | DataSet_11_146 |
| Adra1a | Spdef | knockout | Stomach | Stomach | 2.35442 | 1.23537 | 0.08626149596869 | 0.854802321874054 | DataSet_11_147 |
| Adra1a | Tbx1 | knockout | Ear | Otic vesicles | 3.25271 | 1.70164 | 0.181631075298338 | 0.996209135879357 | DataSet_11_154 |
| Adra1a | Tbx1 | knockout | Ear | Otic vesicles | 0.529228 | -0.918039 | 0.635310376878888 | 0.933394926694296 | DataSet_11_155 |
| Adra1a | Pogz | knockdown | Liver | fetal liver | 0.505197 | -0.985081 | 3.511559e-01 | 0.6260535 | DataSet_11_188 |
| Adra1a | Cpeb1 | siRNA | Neuron | Neuro-2a | 8.48454 | 3.08484 | - | - | DataSet_11_189 |
| Adra1a | Tet1 | shRNA | Embryo | ES cells | 69.2969 | 1.0108 | 22903 | 5.562478e-01 | DataSet_11_191 |
| Adra1a | Ncoa3 | shRNA | Embryo | ES cells | 85.0621 | 0.908936 | 9177 | 1.337889e-02 | DataSet_11_194 |
| Adra1a | Ncoa3 | shRNA | Embryo | ES cells | 85.0621 | 0.908936 | 9177 | 1.337889e-02 | DataSet_11_195 |
| Adra1a | Dnmt3l | shRNA | Embryo | ES cells | 87.2767 | 1.0621 | 17150 | 2.269573e-02 | DataSet_11_231 |
| Adra1a | Bptf | knockout | Embryo | Embryonic fibroblasts | 57.5124 | 0.965779 | 18342 | 4.781859e-01 | DataSet_11_197 |
| Adra1a | Ezh2 | knockdown | Brain | Brain | 5.11519 | 1.06036 | 22879 | 5.760764e-01 | DataSet_11_221 |
| Adra1a | Cebpa | shRNA | Bone_marrow | lineage-negative marrow progenitors | 97.325 | 0.991523 | 26077 | 7.825223e-01 | DataSet_11_199 |
| Adra1a | Dnmt3b | knockout | Heart | Cardiac ventricle | 51.8958 | 0.94991 | 7241 | 2.118574e-01 | DataSet_11_205 |
| Adra1a | Dnmt3a | knockout | Skeletal_muscle | Satellite cells | 0.5 | -1 | 4.932374e-01 | 1.0000000 | DataSet_11_208 |
| Adra1a | Ncl | siRNA | Embryo | ES cells | 0.25 | -2 | 3.454946e-01 | 0.6371969365 | DataSet_11_240 |
| Adra1a | Dnmt3a | siRNA | Embryo | iPSC | 2.29658 | 1.19949 | - | - | DataSet_11_241 |
| Adra1a | Dnmt3b | siRNA | Embryo | iPSC | 0.625638 | -0.676599 | - | - | DataSet_11_242 |
| Adra1a | Kat6a | knockout | Embryo | Embryonic fibroblasts | 2 | 1 | 7.428259e-01 | 0.9152930408 | DataSet_11_245 |
| Adra1a | Fubp1 | shRNA | Brain | brain neural progenitors | 0.181573 | -2.46138 | 0.5042846819 | 1 | DataSet_11_246 |
| Adra1a | Ezh2 | knockout | Calvaria | calvaria | 1.57143 | 0.652077 | 4.034750e-01 | 0.65533111 | DataSet_11_247 |
| Adra1a | Mecp2 | knockout | Adipose_tissue | inguinal adipose tissue | 1.61006 | 0.687115 | 4.869531e-03 | 0.1192917 | DataSet_11_254 |
| Adra1a | Eed | knockout | Brain | Forebrain | 2.25594 | 1.17373 | 2.312786e-02 | 3.917363e-01 | DataSet_11_258 |
| Adra1a | Bcl3 | knockout | Bone | Osteoblast | 13 | 3.70044 | 6.138658e-03 | 3.800744e-01 | DataSet_11_263 |
| Adra1a | Ctnnb1 | knockout | Embryo | MGE cells | 2.21394 | 1.14662 | 6.667157e-04 | 0.024357456 | DataSet_11_266 |
| Adra1a | Mef2d | CRISPR | Heart | Cardiac ventricle | 0.507457 | -0.978643 | 1.139346e-03 | 0.0403491703 | DataSet_11_270 |
| Adra1a | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 0.0230786 | -5.4373 | 3.728329e-01 | 0.81420760 | DataSet_11_272 |
| Adra1a | Ssrp1 | CRISPR | Embryo | ES cells | 0.166667 | -2.58496 | 2.236027e-01 | 0.7914316 | DataSet_11_278 |
| Adra1a | Usp7 | knockout | Embryo | ES cells | 0.25 | -2 | 5.512953e-01 | 0.7863733 | DataSet_11_279 |
| Adra1a | Pcgf6 | knockout | Testis | Testis | 0.363515 | -1.45992 | 6.524576e-01 | 0.9442008 | DataSet_11_282 |
| Adra1a | Setd2 | knockout | Kidney | primary renal tubular epithelial (RTE) cells | 4 | 2 | - | - | DataSet_11_285 |
| Adra1a | Pdx1 | CRISPR | Liver | Liver | 0.609959 | -0.713217 | 2.083284e-02 | 0.320198855 | DataSet_11_286 |
| Adra1a | Kmt2d | CRISPR | Liver | MA1L | 1.5748 | 0.655164 | 6.438942e-01 | 8.181741e-01 | DataSet_11_290 |
| Adra1a | Kmt2d | CRISPR | Liver | MA1L | 1.60519 | 0.682742 | 6.344291e-01 | 8.114216e-01 | DataSet_11_291 |
| Adra1a | Sirt3 | knockout | Pancreatic_islets | pancreatic beta cell | 1.51724 | 0.601451 | 2.683646e-01 | 7.144686e-01 | DataSet_11_297 |
| Adra1a | Tbx20 | knockdown | Heart | primary cardiac fibroblasts | 1.71429 | 0.777608 | 5.388658e-01 | 0.95391488 | DataSet_11_309 |
| Adra1a | Ahr | knockout | Liver | Liver | 0.533848 | -0.905499 | 9.813077e-03 | 0.2735318412 | DataSet_11_315 |
| Adra1a | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.289193 | -1.78989 | 3.464673e-02 | 1.592180e-01 | DataSet_11_320 |
| Adra1a | Bud31 | knockout | Testis | Spermatogonial stem cells | 0.142857 | -2.80735 | 5.352022e-01 | 0.8600602 | DataSet_11_321 |
| Adra1a | Setdb1 | shRNA | Neuron | NE-4C | 2.84517 | 1.50851 | - | - | DataSet_11_323 |
| Adra1a | Padi2 | knockout | Testis | Testis | 0.375 | -1.41504 | 1.948144e-01 | 0.9481885 | DataSet_11_324 |
| Adra1a | Prmt1 | siRNA | Adipose_tissue | 3T3-L1 cells | 0.333333 | -1.58496 | 2.839796e-01 | 0.9832045 | DataSet_11_325 |
| Adra1a | Dnmt3l | knockout | Testis | Spermatogonial progenitor cells | 1.8179 | 0.862275 | - | - | DataSet_11_328 |
| Adra1a | Ezh2 | knockout | Eye | Retina | 0.384615 | -1.37851 | 6.797052e-06 | 5.787979e-04 | DataSet_11_333 |
| Adra1a | Ezh2 | knockout | Eye | Retina | 0.0016823 | -9.21535 | 0.1083171165 | 1.0000000 | DataSet_11_334 |
| Adra1a | Dnmt3b | siRNA | Heart | embryonic cardiomyocytes | 1.54545 | 0.628031 | 2.432872e-01 | 0.70663821 | DataSet_11_338 |
| Adra1a | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 0.363636 | -1.45943 | 6.638203e-02 | 0.133350813 | DataSet_11_340 |
| Adra1a | Dux | shRNA | Embryo | ES cells | 4.75 | 2.24793 | 1.186254e-01 | 6.118724e-01 | DataSet_11_345 |
| Adra1a | Gata4 | CRISPR | Heart | primary cardiac fibroblasts | 1.71429 | 0.777608 | 5.388658e-01 | 0.95391488 | DataSet_11_347 |
| Adra1a | Tbx20 | CRISPR | Heart | primary cardiac fibroblasts | 1.85714 | 0.893085 | 4.986802e-02 | 1.00000000 | DataSet_11_348 |
Regulation Region
Expression Atlas of Adra1a