Gene Overview
Target Gene: CNGB1
NCBI Official Symbol: CNGB1
Entrez ID: 1258
Ensembl ID: ENSG00000070729
Gene Full Name: cyclic nucleotide gated channel beta 1
Strand: -
Gene Locus: 16q21
External Links:

CNGB1 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate CNGB1   
T(co)Fs that Repress CNGB1
The Intensity of the Gene Regulated by T(co)Fs:
CNGB1-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
CNGB1 HOXA1 siRNA Lung_fibroblast IMR-90 2.26455 1.17922 0.08899 0.32248 DataSet_01_110
CNGB1 ID1 siRNA Lung H1650 1.89867 0.92499 0.00394 0.32206 DataSet_01_118
CNGB1 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 0.65663 -0.60685 0.29961 0.99993 DataSet_01_137
CNGB1 POLR3A siRNA Mammary_gland MCF7 2.07459 1.05282 - - DataSet_01_139
CNGB1 MYCN siRNA Autonomic_ganglia SKNBE2 1.51929 0.60339 0.00359 0.08699 DataSet_01_160
CNGB1 ELK1 siRNA Peripheral_blood CD4+ T cells 2.09647 1.06796 0.00045 0.00637 DataSet_01_162
CNGB1 JUN siRNA Peripheral_blood CD4+ T cells 1.57795 0.65805 0.00713 0.05514 DataSet_01_164
CNGB1 NFATC3 siRNA Peripheral_blood CD4+ T cells 1.53485 0.6181 0.01723 0.12505 DataSet_01_166
CNGB1 GABPA shRNA Prostate C4-2B 822.19 9.68333 0.23773 0.43934 DataSet_01_190
CNGB1 GABPA shRNA Prostate LNCaP 621.375 9.27932 0.46218 0.7048 DataSet_01_191
CNGB1 TP63 siRNA Immortalized_keratinocyte HaCaT RG 0.56992 -0.81118 - - DataSet_01_196
CNGB1 TP63 siRNA Head_and_neck SCC-1 1.53846 0.62149 - - DataSet_01_198
CNGB1 TP63 siRNA Head_and_neck SCC-6 1.65618 0.72786 - - DataSet_01_202
CNGB1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 0.25764 -1.95656 - - DataSet_01_209
CNGB1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.46415 -1.10735 - - DataSet_01_210
CNGB1 POSTN shRNA Brain GSC272 2.5572 1.35457 0.15898 0.5782 DataSet_01_293
CNGB1 TFAP4 siRNA Brain BE(2)-C 0.21891 -2.19156 0.33904 0.51625 DataSet_01_295
CNGB1 PTEN shRNA Skin A431 1.68271 0.75078 0.10044 0.26554 DataSet_01_301
CNGB1 HOXC6 siRNA Prostate LNCaP 1.62388 0.69945 0.41741 0.99927 DataSet_01_333
CNGB1 ZNF24 siRNA Embryo_kidney HEK293 0.62136 -0.6865 - - DataSet_01_353
CNGB1 RBM17 shRNA Liver HepG2 0.45139 -1.14756 0.08629 0.34559 DataSet_02_100
CNGB1 RBFOX2 shRNA Liver HepG2 1.90972 0.93336 0.08499 0.65168 DataSet_02_101
CNGB1 SAFB2 shRNA Liver HepG2 1.92308 0.94342 0.07175 0.13537 DataSet_02_102
CNGB1 FIP1L1 shRNA Liver HepG2 0.575 -0.79837 0.82528 0.87145 DataSet_02_103
CNGB1 HDGF shRNA Liver HepG2 0.46667 -1.09954 0.76517 0.86068 DataSet_02_104
CNGB1 U2AF2 shRNA Liver HepG2 0.53846 -0.89308 0.02773 0.10657 DataSet_02_105
CNGB1 HNRNPUL1 shRNA Liver HepG2 3.23077 1.69188 0.12044 0.19732 DataSet_02_109
CNGB1 GTF2F1 shRNA Liver HepG2 5 2.32193 0.01604 0.233 DataSet_02_110
CNGB1 RBM39 shRNA Liver HepG2 1.53472 0.61798 0.25631 0.5079 DataSet_02_111
CNGB1 BCLAF1 shRNA Liver HepG2 0.20513 -2.2854 0.68981 0.77166 DataSet_02_112
CNGB1 U2AF2 shRNA Liver HepG2 0.16667 -2.58496 0.25793 0.40311 DataSet_02_113
CNGB1 XRCC5 shRNA Liver HepG2 4.30769 2.10692 0.03264 0.1819 DataSet_02_114
CNGB1 PCBP1 shRNA Liver HepG2 0.32 -1.64386 0.38244 0.45979 DataSet_02_115
CNGB1 TARDBP shRNA Liver HepG2 0.36585 -1.45066 0.1886 0.27604 DataSet_02_116
CNGB1 SUB1 shRNA Liver HepG2 4.07692 2.02748 0.02099 0.15787 DataSet_02_117
CNGB1 PTBP1 shRNA Liver HepG2 0.36 -1.47393 0.93685 0.95155 DataSet_02_120
CNGB1 RBM34 shRNA Liver HepG2 4.76923 2.25376 0.55069 0.78784 DataSet_02_121
CNGB1 EWSR1 shRNA Liver HepG2 0.28333 -1.81943 0.43975 0.56476 DataSet_02_122
CNGB1 FUS shRNA Liver HepG2 3.07692 1.62149 0.03424 0.14621 DataSet_02_124
CNGB1 HNRNPLL shRNA Liver HepG2 0.21951 -2.18763 0.0811 0.13696 DataSet_02_125
CNGB1 SNRNP70 shRNA Liver HepG2 3.80488 1.92785 0.00295 0.03469 DataSet_02_126
CNGB1 PRPF4 shRNA Liver HepG2 0.6383 -0.6477 0.83862 0.89219 DataSet_02_128
CNGB1 RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.03921 0.24547 DataSet_02_151
CNGB1 GTF2F1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.25 -2 0.03294 0.828 DataSet_02_157
CNGB1 XRCC5 shRNA Haematopoietic_and_lymphoid_tissue K562 0.25 -2 0.03337 0.61377 DataSet_02_159
CNGB1 ZFX siRNA Prostate C4-2B 4 2 0.03723 0.08374 DataSet_02_172
CNGB1 RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.09483 1 DataSet_02_190
CNGB1 ZFX siRNA Mammary_gland MCF7 8 3 0.58771 0.76927 DataSet_02_206
CNGB1 ASCL1 siRNA Lung DMS79 2.14557 1.10136 0.183432953665848 0.824273875812179 DataSet_03_016
CNGB1 ATF4 siRNA Skin A375 0.564998 -0.823683 0.0842289979696763 0.775512819201899 DataSet_03_018
CNGB1 BCL6 siRNA Lymph Pfeiffer DLBCL 0.629323 -0.668128 0.400914002059376 0.796642648288466 DataSet_03_026
CNGB1 CEBPB siRNA Embryo hESC 0.390456 -1.35677 0.013682141748178 0.252298637703741 DataSet_03_049
CNGB1 FOXF2 siRNA Mammary_gland MDA-MB-231 0.630797 -0.664753 - - DataSet_03_087
CNGB1 GATA4 siRNA Stomach KatoIII 0.546392 -0.871993 0.113025237176294 0.897846043350432 DataSet_03_106
CNGB1 GATA6 siRNA Stomach KatoIII 0.596283 -0.745931 0.329731660691765 0.794689584964609 DataSet_03_109
CNGB1 GATA6 siRNA Stomach YCC3 0.622742 -0.683292 0.0316604461385719 0.562499818611123 DataSet_03_110
CNGB1 HIC1 CRISPR Prostate PC3 1.53848 0.621507 - - DataSet_03_118
CNGB1 KLF5 siRNA Stomach YCC3 1.5142 0.598553 0.378504740056382 0.717482505770392 DataSet_03_151
CNGB1 MYB siRNA Cord_Blood CD34+ progenitor cells 8.91093 3.15558 - - DataSet_03_170
CNGB1 MYCN siRNA Autonomic_ganglia SKNBE2 1.51929 0.603394 0.00351427323595134 0.0899126825458161 DataSet_03_185
CNGB1 NR2F2 siRNA Uterus Primary eutopic stromal cells 0.617312 -0.695928 0.148337858989039 0.99947668859931 DataSet_03_202
CNGB1 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 2.50575 1.32524 - - DataSet_03_246
CNGB1 STAT6 siRNA Umbilical_vein HUVEC 2.2585 1.17537 0.297962771052784 0.874631326721835 DataSet_03_264
CNGB1 TFAP2C siRNA Mammary_gland MCF7 1.59305 0.67179 0.233372976007906 0.579525522299124 DataSet_03_274
CNGB1 TFE3 siRNA Kidney UOK257-2 0.386717 -1.37065 - - DataSet_03_275
CNGB1 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 1590.5 10.6353 0.000562302223602876 0.00882794142363261 DataSet_04_014
CNGB1 SMAD2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.285714 -1.80736 0.0730936785598095 0.185787060112884 DataSet_04_018
CNGB1 CIZ1 CRISPR Liver HepG2 0.271186 -1.88264 0.288451423152377 0.52571010226406 DataSet_04_026
CNGB1 E4F1 CRISPR Liver HepG2 3.2 1.67807 0.0441231827017397 0.297050060297447 DataSet_04_028
CNGB1 NFX1 CRISPR Liver HepG2 1.87805 0.909235 0.327267112276354 0.421969582628887 DataSet_04_032
CNGB1 PAN2 CRISPR Liver HepG2 1.80645 0.853159 0.218306691998877 0.394008598587378 DataSet_04_033
CNGB1 SMAD2 CRISPR Liver HepG2 1.60714 0.684498 0.0191407130137385 0.541467675849801 DataSet_04_034
CNGB1 WRN shRNA Liver HepG2 1.72581 0.787271 0.0570523635607939 0.251567285247435 DataSet_04_038
CNGB1 ZC3H8 shRNA Liver HepG2 1.87805 0.909235 0.943775188582292 0.970173953187866 DataSet_04_040
CNGB1 CHCHD3 CRISPR Liver HepG2 2.15625 1.10852 0.0649074898155291 0.469797184022495 DataSet_04_067
CNGB1 CNOT7 CRISPR Liver HepG2 0.5 -1 0.099303863491445 0.211984339992017 DataSet_04_045
CNGB1 DNMT3B CRISPR Liver HepG2 2.93333 1.55254 0.0569443472214758 0.237774503200173 DataSet_04_044
CNGB1 ABT1 shRNA Liver HepG2 1.53659 0.619728 0.647040063147021 0.758118018007883 DataSet_04_052
CNGB1 CALR shRNA Liver HepG2 2.83333 1.5025 0.368632408674291 0.511906098732849 DataSet_04_053
CNGB1 CCAR1 shRNA Liver HepG2 2.375 1.24793 0.444148904049831 0.600607037254673 DataSet_04_054
CNGB1 CNOT7 shRNA Liver HepG2 0.105528 -3.24431 0.000286988958878641 0.00390334239264641 DataSet_04_051
CNGB1 DDX1 shRNA Liver HepG2 2.23077 1.15754 0.459232480017846 0.684809867596645 DataSet_04_057
CNGB1 PRPF6 shRNA Liver HepG2 0.615385 -0.70044 0.706462469455057 0.856190518320899 DataSet_04_056
CNGB1 UBE2L3 shRNA Liver HepG2 6.07692 2.60334 0.0279444844514357 0.0800046105476434 DataSet_04_055
CNGB1 ACTN4 CRISPR Haematopoietic_and_lymphoid_tissue K562 2 1 0.68134535447588 0.834543540844122 DataSet_04_048
CNGB1 DDX17 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.588235 -0.765535 0.613094267206389 0.928346265048922 DataSet_04_047
CNGB1 DDX20 CRISPR Haematopoietic_and_lymphoid_tissue K562 5 2.32193 0.444867334898649 0.784347982333687 DataSet_04_050
CNGB1 RIOK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.25 1.16992 0.443685514278085 0.846294806439748 DataSet_04_076
CNGB1 SMG7 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.125 -3 0.582089243412578 0.846744876953634 DataSet_04_075
CNGB1 SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.625 -0.678072 0.795167815104543 0.896473504265849 DataSet_04_049
CNGB1 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4 2 0.318460921233681 0.579150445002135 DataSet_02_38
CNGB1 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.222222 -2.16992 0.514846280118698 0.674761150697605 DataSet_02_14
CNGB1 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.444444 -1.16992 0.698307879090345 0.827171297132997 DataSet_02_34
CNGB1 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.464286 -1.10692 0.498582465548109 0.809287731875865 DataSet_02_75
CNGB1 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 9 3.16992 0.0921040441740339 0.57325260957571 DataSet_02_45
CNGB1 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 7.83333 2.96963 0.0554985111951812 0.380772599163985 DataSet_02_32
CNGB1 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.368421 -1.44057 0.608136694086813 0.898642618236412 DataSet_02_49
CNGB1 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.333333 -1.58496 0.583319376281505 0.731300654869917 DataSet_02_33
CNGB1 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.33333 1.22239 0.295284142443864 0.46491368029885 DataSet_02_53
CNGB1 ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.724641662784442 0.83612499552051 DataSet_04_060
CNGB1 ESR1 siRNA Mammary_gland MCF7 0.545622 -0.874026 2.222933e-02 0.1121864099 DataSet_03_352
CNGB1 ETV5 knockdown Colon HT29 0.176471 -2.5025 3.957226e-02 0.232929406 DataSet_03_353
CNGB1 TET1 CRISPR Mammary_gland Hs578T 31.817 4.99173 1.957602e-02 7.591857e-02 DataSet_03_355
CNGB1 CREBBP CRISPR Brain U5-NPC 1.66667 0.736966 0.8203643331 0.8901104 DataSet_03_356
CNGB1 TP53 CRISPR Brain U5-NPC 3.66667 1.87447 2.344132e-01 3.671047e-01 DataSet_03_358
CNGB1 ZNF148 shRNA Mammary_gland MDA-MB-231 0.526643 -0.925102 1.316014e-01 0.320965878 DataSet_03_366
CNGB1 GLI1 siRNA Skeletal_muscle RMS13 3.22985 1.69147 4.459592e-02 0.180220005 DataSet_03_375
CNGB1 SMARCA2 shRNA Lung NCI-H1944 1.51456 0.598902 3.017302e-02 3.254838e-01 DataSet_03_377
CNGB1 EZH2 CRISPR Ovary SKOV3 3.5 1.80735 3.781134e-01 0.5556787519 DataSet_03_378
CNGB1 DNMT1 siRNA Skin Human melanoma cells 4.28705 2.09998 8.021879e-01 8.640168e-01 DataSet_03_382
CNGB1 KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 2.40806 1.26787 0.2625176425 0.8388073 DataSet_03_387
CNGB1 NFKBIA shRNA Bone_marrow U2OS 0.0113004 -6.46749 6.325238e-01 0.87005461 DataSet_03_389
CNGB1 YY1 knockdown Liver HepG2 3.5 1.80735 4.647619e-01 6.230132e-01 DataSet_03_390
CNGB1 ILF2 siRNA Stomach SGC-7901 1.56098 0.642448 0.5886392945 0.66421254 DataSet_03_393
CNGB1 RELA CRISPR Brain T30 0.107001 -3.2243 0.0428944383 0.8400824 DataSet_03_399
CNGB1 HMGA1 shRNA Bile_duct HUCCT1 3.27526 1.71161 3.069559e-04 0.021718833 DataSet_03_400
CNGB1 EHF shRNA Stomach MKN7 0.52295 -0.935254 - - DataSet_03_402
CNGB1 CDK7 shRNA Bone_marrow D458 0.639535 -0.644905 2.866447e-01 0.60204620 DataSet_03_404
CNGB1 STRAP knockout Nerve SK-N-AS 0.463765 -1.10853 - - DataSet_03_409
CNGB1 ZKSCAN3 CRISPR Colon HCT116 0.585366 -0.77259 6.207668e-02 0.439319430 DataSet_03_415
CNGB1 NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 2.3 1.20163 7.687550e-01 0.852037709 DataSet_03_418
CNGB1 FOXK2 shRNA Ovary OVCAR-5 0.0851064 -3.55459 4.657754e-02 0.17600087 DataSet_03_419
CNGB1 MAEL CRISPR Liver Alexander cells 0.615385 -0.70044 - - DataSet_03_423
CNGB1 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 6 2.58496 2.076849e-01 0.562696016 DataSet_03_434
CNGB1 SUFU shRNA Mammary_gland HCC1954 cells 10.5 3.39232 0.0012088936 0.2904148 DataSet_03_437
CNGB1 SETDB1 shRNA Colon HCT116 2.90081 1.53646 - - DataSet_03_440
CNGB1 HMG20A siRNA Mammary_gland MDA-MB-231 0.578947 -0.788496 0.2325634653 0.4905665 DataSet_03_442
CNGB1 PHF14 siRNA Mammary_gland MDA-MB-231 1.52632 0.610053 0.2015749037 0.5994811 DataSet_03_443
CNGB1 FOSL1 siRNA Prostate MSKPCa3 0.527473 -0.922832 0.0606148832 0.4547882 DataSet_03_445
CNGB1 RELB CRISPR Colon SW480 0.307692 -1.70044 3.052162e-01 5.110708e-01 DataSet_03_449
CNGB1 CBX2 siRNA Mammary_gland MDA-MB-231 1.87992 0.910674 2.674062e-01 4.765508e-01 DataSet_03_450
CNGB1 HAND1 siRNA Placenta HPMVEC 0.1875 -2.41504 1.509539e-01 0.9463341 DataSet_03_459
CNGB1 SOX9 knockout Liver HuH7 0.5 -1 4.526739e-01 5.717813e-01 DataSet_03_463
CNGB1 STAT3 shRNA Liver HepG2 1.52479 0.608614 8.918537e-02 0.4027468848 DataSet_03_465
CNGB1 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 0.5 -1 - - DataSet_03_467
CNGB1 LIN28A siRNA Mammary_gland MCF7M 3.92575 1.97297 7.750726e-01 0.9636736 DataSet_03_469
CNGB1 LIN28A siRNA Mammary_gland MCF7M 3.92575 1.97297 7.750726e-01 0.9636736 DataSet_03_470
CNGB1 EZH2 siRNA Prostate LNCaP 0.333333 -1.58496 7.911707e-01 1.0000000 DataSet_03_475
CNGB1 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.117647 -3.08746 0.3160554 0.9053673 DataSet_04_071
CNGB1 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.235294 -2.08746 0.3661273 0.527778083 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate POLR2G by the evidences of both expression and ChIP-seq/motif
Expression Atlas of CNGB1
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines