Gene Overview
| Target Gene: | Crisp3 |
| NCBI Official Symbol: | Crisp3 |
| Entrez ID: | 11572 |
| Ensembl ID: | ENSMUSG00000025433 |
| Gene Full Name: | cysteine-rich secretory protein 3 |
| Strand: | - |
| Gene Locus: | 17 B2|17 19.45 cM |
| External Links: |
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Crisp3 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Crisp3
T(co)Fs
that Repress Crisp3
The Intensity of the Gene Regulated by T(co)Fs:
Crisp3-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Crisp3 | Adnp | knockout | Embryo | Whole embryonic body | 2.1875 | 1.12928 | 0.174638388777201 | 0.538738330940756 | DataSet_11_001 |
| Crisp3 | Bcl6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 2.21739 | 1.14886 | 0.760189485712246 | 0.906169553257501 | DataSet_11_014 |
| Crisp3 | Bcl6 | knockout | Bone_marrow | Myeloid cells | 0.480802 | -1.05649 | 0.0129743061396281 | 0.0892241656638016 | DataSet_11_015 |
| Crisp3 | E2f4 | knockout | Brain | Forebrain | 11.5713 | 3.53247 | - | - | DataSet_11_033 |
| Crisp3 | Foxp1 | knockout | Eye | Lens | 0.583333 | -0.777608 | - | - | DataSet_11_044 |
| Crisp3 | Gfi1 | knockout | Cord_Blood | T-cells | 0.620739 | -0.687942 | 0.686013865297554 | 0.892751907837786 | DataSet_11_053 |
| Crisp3 | Hoxc13 | knockout | Skin | Skin | 0.438911 | -1.188 | 0.00120357269416571 | 0.054006859266658 | DataSet_11_057 |
| Crisp3 | Irf6 | knockout | Skin | Skin | 0.374065 | -1.41864 | 0.224068774919774 | 0.545406696468844 | DataSet_11_062 |
| Crisp3 | Jarid2 | knockout | Pancreas | Embryonic pancreas | 1.53333 | 0.616671 | 0.284411171609828 | 0.84648396208457 | DataSet_11_064 |
| Crisp3 | Lhx8 | knockout | Ovary | Ovary | 3.66013 | 1.87189 | 0.841321145707417 | 0.907192195639072 | DataSet_11_070 |
| Crisp3 | Lmx1b | knockout | Kidney | Kidney | 4.91542 | 2.29732 | 0.0818496706375926 | 0.48710601763909 | DataSet_11_072 |
| Crisp3 | Mafg | knockout | Embryo | Whole embryo | 0.072163 | -3.7926 | 0.000163147309760097 | 0.0435220625839034 | DataSet_11_073 |
| Crisp3 | Mbd1 | siRNA | Adipose_tissue | 3T3-L1 cells | 0.574468 | -0.799701 | - | - | DataSet_11_074 |
| Crisp3 | Neurod1 | knockout | Eye | Pineal gland | 0.610837 | -0.71114 | 0.448856962589184 | 0.870514969643086 | DataSet_11_087 |
| Crisp3 | Neurod1 | knockout | Eye | Pineal gland | 0.468013 | -1.09538 | 0.108051165663971 | 0.9983937273602 | DataSet_11_089 |
| Crisp3 | Nr2f2 | knockout | Ovary | E14.5 Ovary | 4.16667 | 2.05889 | 0.0241959879916277 | 0.797852125491812 | DataSet_11_094 |
| Crisp3 | Nr2f2 | knockout | Ovary | E16.5 Ovary | 0.509379 | -0.973189 | 0.383303438290271 | 0.727732978014542 | DataSet_11_095 |
| Crisp3 | Otx2 | knockout | Eye | Retina | 0.591398 | -0.757799 | 0.596608512970976 | 0.999923528647439 | DataSet_11_097 |
| Crisp3 | Pitx2 | knockout | Eye | Cornea | 1.76048 | 0.815969 | 0.165598866573059 | 0.547686129960004 | DataSet_11_103 |
| Crisp3 | Plagl2 | knockout | Intestine | Small intestine | 1.58333 | 0.662965 | 0.89529717544143 | 0.961044436933995 | DataSet_11_104 |
| Crisp3 | Runx1 | knockout | Bone_marrow | KSL cells | 0.636248 | -0.652338 | 0.0642352862083469 | 0.816127613581891 | DataSet_11_115 |
| Crisp3 | Runx1 | knockout | Mammary_gland | Luminal epithelial cells | 0.455094 | -1.13576 | 0.968020731259476 | 0.999784944667092 | DataSet_11_117 |
| Crisp3 | Sall1 | knockout | Kidney | Kidney | 1.51305 | 0.597461 | 0.279881980124564 | 0.945620084902242 | DataSet_11_122 |
| Crisp3 | Sall4 | shRNA | Embryo | ES cells | 1.58621 | 0.665581 | 0.922908842734328 | 0.999840995136314 | DataSet_11_123 |
| Crisp3 | Smad4 | siRNA | Brain | bEnd3 | 0.209844 | -2.25261 | - | - | DataSet_11_127 |
| Crisp3 | Sox11 | knockout | Brain | Cortex | 0.409985 | -1.28636 | - | - | DataSet_11_138 |
| Crisp3 | Sp3 | knockout | Heart | Heart | 0.1127 | -3.14944 | 0.0372167334985271 | 0.680640667436733 | DataSet_11_145 |
| Crisp3 | Spdef | knockout | Stomach | Stomach | 0.492738 | -1.02111 | 0.21876871537866 | 0.895948589880502 | DataSet_11_147 |
| Crisp3 | Stat3 | knockout | Lung | Lung typeII cells | 0.575387 | -0.797395 | 0.747935974898225 | 0.945491924766091 | DataSet_11_151 |
| Crisp3 | Stat4 | knockout | Lymph | Lamina propria lymphocytes | 0.125042 | -2.99952 | 0.00770663818683514 | 0.683916327523024 | DataSet_11_152 |
| Crisp3 | Tbx1 | knockout | Ear | Otic vesicles | 0.282994 | -1.82116 | 0.226467762276724 | 0.819504834074279 | DataSet_11_155 |
| Crisp3 | Vdr | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.295393 | -1.75929 | 0.502292083069092 | 0.999827445128963 | DataSet_11_174 |
| Crisp3 | Wt1 | siRNA | Embryo_kidney | LB-22 | 0.483155 | -1.04944 | 0.128311191902658 | 0.342694521923125 | DataSet_11_179 |
| Crisp3 | Dnmt1 | siRNA | Pituitary_gland | AtT-20 | 3.13504 | 1.64848 | 2.174148e-01 | 0.9999923 | DataSet_11_187 |
| Crisp3 | Pogz | knockdown | Liver | fetal liver | 0.461339 | -1.1161 | 2.775532e-01 | 0.5691215 | DataSet_11_188 |
| Crisp3 | Kdm5b | knockout | Heart | left ventricles | 0.609289 | -0.714803 | 0.3030776037 | 0.9999827 | DataSet_11_210 |
| Crisp3 | Dnmt1 | knockout | Embryo | Embryonic fibroblasts | 3.9 | 1.96347 | 1.218181e-01 | 2.751398e-01 | DataSet_11_192 |
| Crisp3 | Smarca4 | shRNA | Embryo | ES cells | 3.20122 | 1.67862 | - | - | DataSet_11_224 |
| Crisp3 | Smarca4 | shRNA | Embryo | ES cells | 3.20122 | 1.67862 | - | - | DataSet_11_225 |
| Crisp3 | Crebbp | knockout | Spleen | Germinal center B cells | 0.358629 | -1.47943 | 1.556314e-04 | 0.038740126 | DataSet_11_227 |
| Crisp3 | Bcl11b | knockout | Main_olfactory_epithelium | main olfactory epithelium (MOE) | 4.49088 | 2.167 | - | - | DataSet_11_207 |
| Crisp3 | Dnmt3b | siRNA | Embryo | iPSC | 0.333673 | -1.58349 | - | - | DataSet_11_242 |
| Crisp3 | Kmt2d | knockout | Skin | iBiP melanoma mouse model tumor cell | 0.142857 | -2.80735 | 5.046156e-01 | 6.356114e-01 | DataSet_11_250 |
| Crisp3 | Zbp1 | siRNA | Bone_marrow | bone marrow-derived mesenchymal stem_progenitor cells | 0.384925 | -1.37735 | 2.102397e-01 | 0.399531955 | DataSet_11_252 |
| Crisp3 | Kat6b | shRNA | Bone_marrow | LT-HSCs | 6 | 2.58496 | 2.522357e-01 | 0.6076680 | DataSet_11_271 |
| Crisp3 | Lin28b | knockout | Bone_marrow | Bone marrow immature B cells | 3 | 1.58496 | 7.120450e-01 | 0.9858719 | DataSet_11_274 |
| Crisp3 | Med19 | knockout | White_adipose_tissue | Gonadal white adipose tissue | 0.127122 | -2.97571 | 8.163304e-02 | 3.704409e-01 | DataSet_11_289 |
| Crisp3 | Sirt3 | knockout | Pancreatic_islets | pancreatic beta cell | 0.610169 | -0.712718 | 5.351193e-01 | 8.105027e-01 | DataSet_11_297 |
| Crisp3 | Jmjd6 | knockout | Bone_marrow | Lin-Sca1+Kit+ (LSK) haematopoietic stem and progenitor cells | 1.6 | 0.678072 | - | - | DataSet_11_306 |
| Crisp3 | Cited2 | knockout | Haematopoietic_and_lymphoid_tissue | Hematopoietic stem cell (HSC) | 2.42857 | 1.28011 | - | - | DataSet_11_308 |
| Crisp3 | Satb2 | knockout | Colon | Intestine epithelium | 0.46875 | -1.09311 | 7.947360e-02 | 0.4161690369 | DataSet_11_316 |
| Crisp3 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.0122449 | -6.35168 | 1.569216e-04 | 7.837733e-02 | DataSet_11_319 |
| Crisp3 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.586751 | -0.76918 | 4.449083e-01 | 6.453537e-01 | DataSet_11_320 |
| Crisp3 | Snai1 | knockdown | Heart | Heart | 0.515183 | -0.956844 | 3.758717e-01 | 0.56276955 | DataSet_11_326 |
| Crisp3 | Dnmt1 | knockout | Kidney | kidney Cap Mesenchyme | 9.89388 | 3.30654 | 1.932448e-01 | 4.668990e-01 | DataSet_11_344 |
Regulation Region
Expression Atlas of Crisp3