Gene Overview
| Target Gene: | Crlf1 |
| NCBI Official Symbol: | Crlf1 |
| Entrez ID: | 12931 |
| Ensembl ID: | ENSMUSG00000007888 |
| Gene Full Name: | cytokine receptor-like factor 1 |
| Strand: | + |
| Gene Locus: | 8 B3.3|8 34.15 cM |
| External Links: |
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Crlf1 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Crlf1
T(co)Fs
that Repress Crlf1
The Intensity of the Gene Regulated by T(co)Fs:
Crlf1-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Crlf1 | Atoh1 | knockout | Gastrointestinal_tissue | Intestinal epithelial Lgr5(hi) stem cells | 0.498356 | -1.00475 | 0.00646605078337756 | 0.020103062943645 | DataSet_11_010 |
| Crlf1 | Bhlha9 | knockout | Limb | Whole limb bud | 0.230364 | -2.11801 | - | - | DataSet_11_016 |
| Crlf1 | Cebpb | shRNA | Mammary_gland | 4T1 mammary tumor cells | 0.163719 | -2.61071 | 0.120199606669514 | 0.999984070881864 | DataSet_11_022 |
| Crlf1 | Foxa2 | knockout | Lung | Whole lung | 0.239622 | -2.06117 | 0.000525016337486678 | 0.0646417538962562 | DataSet_11_041 |
| Crlf1 | Foxq1 | siRNA | Mammary_gland | NM18 | 1.8266 | 0.869158 | 7.30056305364874e-06 | 0.000388715394805779 | DataSet_11_045 |
| Crlf1 | Gata4 | knockout | Intestine | Jejunum | 2.53335 | 1.34105 | 0.036554351976666 | 0.461005597815017 | DataSet_11_049 |
| Crlf1 | Hsf4 | knockout | Eye | Lens | 0.627556 | -0.672183 | 0.987146577165427 | 0.996910983336243 | DataSet_11_058 |
| Crlf1 | Irf6 | knockout | Skin | Skin | 0.652753 | -0.615391 | 0.122919538347576 | 0.420983181120718 | DataSet_11_062 |
| Crlf1 | Klf17 | shRNA | Mammary_gland | 168FARN | 0.44822 | -1.15772 | 0.0439613266077674 | 0.106948083725196 | DataSet_11_066 |
| Crlf1 | Lhx8 | knockout | Gonads | Oocytes | 0.47988 | -1.05926 | 0.0121874999039465 | 0.993830266659981 | DataSet_11_069 |
| Crlf1 | Lhx8 | knockout | Ovary | Ovary | 0.252458 | -1.98589 | 0.00321886028195263 | 0.028801717475401 | DataSet_11_070 |
| Crlf1 | Mafg | knockout | Embryo | Whole embryo | 0.243926 | -2.03548 | 0.0378878911851433 | 1 | DataSet_11_073 |
| Crlf1 | Meis1 | knockout | Hematopoietic | KSL hematopoietic cells | 0.654095 | -0.612427 | 0.242983009150847 | 0.995635220774426 | DataSet_11_081 |
| Crlf1 | Nhlh2 | knockout | Eye | Retina | 0.609929 | -0.713287 | 0.4367189793707 | 0.586597800488337 | DataSet_11_092 |
| Crlf1 | Nr2f2 | knockout | Ovary | E14.5 Ovary | 0.354681 | -1.49541 | 0.398368423631427 | 0.886621376901281 | DataSet_11_094 |
| Crlf1 | Nrf1 | knockdown | Liver | Liver | 2.06914 | 1.04903 | 0.0252114836389074 | 0.0757993235660931 | DataSet_11_096 |
| Crlf1 | Otx2 | knockout | Eye | Retina | 0.525932 | -0.927051 | 0.746624223474475 | 0.999923528647439 | DataSet_11_097 |
| Crlf1 | Pitx2 | knockout | Eye | Cornea | 1.72882 | 0.789789 | 0.209492627593015 | 0.5991206486602 | DataSet_11_103 |
| Crlf1 | Plagl2 | knockout | Intestine | Small intestine | 1.52381 | 0.607683 | 0.287511063617756 | 0.59716494225024 | DataSet_11_104 |
| Crlf1 | Prdm2 | shRNA | Muscle | C2C12 | 2.47791 | 1.30912 | 0.0110860674131977 | 0.616995971138261 | DataSet_11_108 |
| Crlf1 | Sall1 | knockout | Kidney | Kidney | 0.549745 | -0.863165 | 0.00340243414393145 | 0.367418939076116 | DataSet_11_122 |
| Crlf1 | Smad4 | siRNA | Brain | bEnd3 | 200.695 | 7.64886 | - | - | DataSet_11_127 |
| Crlf1 | Smad4 | knockout | Aorta | Aortic arteries | 2.42765 | 1.27956 | 0.0631929795638801 | 0.372952858456289 | DataSet_11_128 |
| Crlf1 | Snai1 | knockout | Embryo | Teratoma | 3.51305 | 1.81272 | - | - | DataSet_11_130 |
| Crlf1 | Stat3 | knockout | Lung | Lung typeII cells | 0.574525 | -0.799558 | 0.12595628313732 | 0.732737118940182 | DataSet_11_151 |
| Crlf1 | Stat4 | knockout | Lymph | Lamina propria lymphocytes | 1.55215 | 0.634265 | 0.133106514767934 | 0.916250386397509 | DataSet_11_152 |
| Crlf1 | Stat6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 1.67335 | 0.74274 | 0.607665329290514 | 0.77398591223376 | DataSet_11_153 |
| Crlf1 | Tbx1 | knockout | Ear | Otic vesicles | 1.511 | 0.5955 | 0.0274603612077968 | 0.638404688804985 | DataSet_11_155 |
| Crlf1 | Thap11 | knockout | Heart | Heart | 1.68197 | 0.750151 | 0.0828564702706157 | 0.999994817864919 | DataSet_11_167 |
| Crlf1 | Yy1 | knockout | Muscle | Skeletal muscle | 1.56233 | 0.643699 | 0.00269726423246838 | 0.012001858908078 | DataSet_11_182 |
| Crlf1 | Yy1 | knockout | White_adipose_tissue | Visceral white adipose tissue | 1.91395 | 0.936554 | 0.000619442638727709 | 0.0180607054131678 | DataSet_11_185 |
| Crlf1 | Hipk2 | knockout | Heart | cardiac tissue | 0.302995 | -1.72264 | 1.582008e-04 | 3.289334e-02 | DataSet_11_238 |
| Crlf1 | Tet1 | shRNA | Embryo | ES cells | 3.41042 | 1.76995 | 4.060058e-03 | 0.13602434 | DataSet_11_213 |
| Crlf1 | Tet1 | shRNA | Embryo | ES cells | 3.41042 | 1.76995 | 4.060058e-03 | 0.13602434 | DataSet_11_214 |
| Crlf1 | Dnmt1 | knockout | Embryo | Embryonic fibroblasts | 0.308358 | -1.69732 | 1.751557e-02 | 8.368479e-02 | DataSet_11_192 |
| Crlf1 | Ezh2 | knockdown | Brain | Brain | 2.0953 | 1.06716 | 4.997372e-03 | 0.0672466770 | DataSet_11_221 |
| Crlf1 | Bptf | shRNA | Mammary_gland | 4T1 cells | 2.43401 | 1.28333 | 1.113110e-02 | 0.230537526 | DataSet_11_223 |
| Crlf1 | Smarca4 | shRNA | Embryo | ES cells | 0.362472 | -1.46406 | - | - | DataSet_11_224 |
| Crlf1 | Smarca4 | shRNA | Embryo | ES cells | 0.362472 | -1.46406 | - | - | DataSet_11_225 |
| Crlf1 | Bcl11b | knockdown | Embryo | Embryonic fibroblasts | 2.85886 | 1.51544 | - | - | DataSet_11_226 |
| Crlf1 | Dnmt3a | knockout | Skeletal_muscle | Satellite cells | 0.64648 | -0.629322 | 3.378731e-01 | 1.0000000 | DataSet_11_208 |
| Crlf1 | Dnmt3a | siRNA | Embryo | iPSC | 1.86674 | 0.900518 | - | - | DataSet_11_241 |
| Crlf1 | Lin28a | knockout | Heart | Heart | 0.201179 | -2.31345 | 0.4997030645 | 0.8803564 | DataSet_11_243 |
| Crlf1 | Twist1 | knockout | Bone_marrow | stromal cells | 3.85811e-20 | -64.4907 | - | - | DataSet_11_244 |
| Crlf1 | Kat6a | knockout | Embryo | Embryonic fibroblasts | 2.29706 | 1.19979 | 6.950689e-03 | 0.0809216377 | DataSet_11_245 |
| Crlf1 | Fubp1 | shRNA | Brain | brain neural progenitors | 0.371812 | -1.42735 | 0.6518574605 | 1 | DataSet_11_246 |
| Crlf1 | Kdm2a | CRISPR | Embryo | ES cells | 0.662791 | -0.593375 | 0.0838648723 | 1.0000000 | DataSet_11_251 |
| Crlf1 | Zbp1 | siRNA | Bone_marrow | bone marrow-derived mesenchymal stem_progenitor cells | 0.514655 | -0.958323 | 9.640664e-04 | 0.022697504 | DataSet_11_252 |
| Crlf1 | Crebbp | shRNA | Lung | preSC | 0.586173 | -0.770601 | 7.193837e-03 | 0.25835009 | DataSet_11_255 |
| Crlf1 | Brca1 | siRNA | Embryo | Embryonic fibroblasts | 2.0841 | 1.05943 | 0.0196089740 | 0.3808902 | DataSet_11_256 |
| Crlf1 | Eed | knockout | Brain | hindbrain | 5.66202 | 2.50132 | 6.451906e-05 | 2.278522e-02 | DataSet_11_259 |
| Crlf1 | Eed | knockout | Brain | midbrain | 13.3659 | 3.74048 | 5.673457e-04 | 6.843270e-02 | DataSet_11_260 |
| Crlf1 | Eed | knockout | Spinal_cord | spinal cord | 2.84202 | 1.50692 | 1.236269e-01 | 9.999790e-01 | DataSet_11_261 |
| Crlf1 | Bcl3 | knockout | Bone | Osteoblast | 0.524026 | -0.932289 | 3.764099e-02 | 6.699600e-01 | DataSet_11_263 |
| Crlf1 | Nsd2 | knockout | Bone_marrow | Bone marrow immature B cells | 4.63865 | 2.21371 | 4.253068e-02 | 0.19735540 | DataSet_11_267 |
| Crlf1 | Nr4a1 | knockout | Mammary_gland | PyVT mouse mammary tumor cells | 1.67038 | 0.740173 | 1.137845e-01 | 0.7273107 | DataSet_11_268 |
| Crlf1 | Dux | knockout | Embryo | Embryo | 4.06766 | 2.0242 | 3.127613e-03 | 1.729040e-02 | DataSet_11_269 |
| Crlf1 | Mef2d | CRISPR | Heart | Cardiac ventricle | 7.27792 | 2.86353 | 1.481808e-02 | 0.1247890940 | DataSet_11_270 |
| Crlf1 | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 0.00051037 | -10.9362 | 3.440144e-01 | 0.81420760 | DataSet_11_272 |
| Crlf1 | Dux | knockout | Embryo | Embryo | 4.06766 | 2.0242 | 3.127605e-03 | 1.728866e-02 | DataSet_11_273 |
| Crlf1 | Lin28b | knockout | Bone_marrow | Bone marrow immature B cells | 0.375 | -1.41504 | 4.121923e-01 | 0.9643594 | DataSet_11_274 |
| Crlf1 | Myod1 | CRISPR | Skeletal_muscle | myoblast | 0.171661 | -2.54236 | 5.194158e-07 | 1.729667e-05 | DataSet_11_275 |
| Crlf1 | Ezh2 | siRNA | Bone_marrow | Mesenchymal stem cells | 2.11054 | 1.07762 | 8.326472e-04 | 2.307622e-02 | DataSet_11_276 |
| Crlf1 | Usp7 | knockout | Embryo | ES cells | 1.78947 | 0.839535 | 2.595597e-01 | 0.5913015 | DataSet_11_279 |
| Crlf1 | Pcgf6 | knockout | Liver | Liver | 0.402445 | -1.31314 | 5.046719e-01 | 0.9710425 | DataSet_11_281 |
| Crlf1 | Setd2 | knockout | Kidney | primary renal tubular epithelial (RTE) cells | 0.666294 | -0.585769 | - | - | DataSet_11_285 |
| Crlf1 | Pdx1 | CRISPR | Liver | Liver | 0.333333 | -1.58496 | 6.912503e-02 | 0.385115788 | DataSet_11_286 |
| Crlf1 | Usp7 | siRNA | Embryo | ES cells | 0.517857 | -0.949374 | 1.324162e-01 | 0.6667924 | DataSet_11_287 |
| Crlf1 | Med19 | knockout | White_adipose_tissue | Gonadal white adipose tissue | 0.604286 | -0.726697 | 1.564491e-02 | 1.500061e-01 | DataSet_11_289 |
| Crlf1 | Mkl1 | knockout | Bone_marrow | Bone marrow differentiated macrophages | 21 | 4.39232 | 1.734331e-02 | 0.3103677619 | DataSet_11_294 |
| Crlf1 | Tfap2a | knockout | Brain | Brain | 0.292079 | -1.77557 | 0.1153790367 | 0.9599640 | DataSet_11_295 |
| Crlf1 | Ssrp1 | CRISPR | Embryo | ES cells | 0.527027 | -0.924051 | 3.873917e-02 | 0.24851218 | DataSet_11_296 |
| Crlf1 | Brpf1 | shRNA | Nerve | Neural progenitor cells | 1.50164 | 0.586541 | 1.493672e-01 | 0.9999903 | DataSet_11_299 |
| Crlf1 | Arid2 | knockout | Muscle | LSK | 19 | 4.24793 | 7.647587e-06 | 1.659942e-03 | DataSet_11_301 |
| Crlf1 | Dnmt1 | knockout | Skin | Keratinocytes | 1.90837 | 0.932344 | 1.396837e-01 | 0.5017606521 | DataSet_11_303 |
| Crlf1 | Jmjd6 | knockout | Bone_marrow | Lin-Sca1+Kit+ (LSK) haematopoietic stem and progenitor cells | 0.5 | -1 | - | - | DataSet_11_306 |
| Crlf1 | Esr1 | knockout | Liver | Liver | 0.533333 | -0.906891 | 2.511173e-01 | 1.0000000 | DataSet_11_307 |
| Crlf1 | Myc | CRISPR | Skeletal_muscle | quiescent muscle stem cell | 93.3607 | 6.54474 | 3.225899e-01 | 0.80359421 | DataSet_11_310 |
| Crlf1 | Irf7 | knockout | Bone_marrow | c-kit+ leukemic cells | 2 | 1 | - | - | DataSet_11_313 |
| Crlf1 | Actl6a | knockout | Nerve | sciatic nerve | 4.29286 | 2.10194 | 3.652886e-03 | 0.086330307 | DataSet_11_314 |
| Crlf1 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.253353 | -1.98078 | 6.104834e-03 | 2.330839e-01 | DataSet_11_319 |
| Crlf1 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 30.5522 | 4.93321 | 2.591008e-04 | 1.500571e-02 | DataSet_11_320 |
| Crlf1 | Bud31 | knockout | Testis | Spermatogonial stem cells | 1.90805 | 0.932096 | 7.437015e-01 | 0.9259818 | DataSet_11_321 |
| Crlf1 | Setdb1 | shRNA | Neuron | NE-4C | 11.5229 | 3.52644 | - | - | DataSet_11_323 |
| Crlf1 | Snai1 | knockdown | Heart | Heart | 0.618333 | -0.693544 | 2.658973e-02 | 0.12717700 | DataSet_11_326 |
| Crlf1 | Kdm5b | siRNA | Embryo | ES cells | 1.67913 | 0.747711 | 0.8383906991 | 0.9641032 | DataSet_11_331 |
| Crlf1 | Ezh2 | knockout | Eye | Retina | 0.228571 | -2.12928 | 2.449528e-04 | 8.002957e-03 | DataSet_11_333 |
| Crlf1 | Dnmt3a | knockout | Peritoneum | peritoneal macrophages | 0.492569 | -1.0216 | - | - | DataSet_11_336 |
| Crlf1 | Gtf2ird1 | knockout | Lip | Lip | 0.513995 | -0.960174 | 2.421193e-02 | 3.022064e-01 | DataSet_11_339 |
| Crlf1 | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 0.136827 | -2.86958 | 7.953852e-04 | 0.009358970 | DataSet_11_340 |
| Crlf1 | Ezh2 | knockout | Small_intestinal_crypts | small intestinal crypts | 9.625 | 3.26679 | 0.0151383718 | 0.1712697 | DataSet_11_341 |
| Crlf1 | Dnmt1 | knockout | Kidney | kidney Cap Mesenchyme | 0.537873 | -0.894663 | 2.218534e-01 | 5.035844e-01 | DataSet_11_344 |
Regulation Region
Expression Atlas of Crlf1