Gene Overview
Target Gene: DDIT3
NCBI Official Symbol: DDIT3
Entrez ID: 1649
Ensembl ID: ENSG00000175197
Gene Full Name: DNA damage inducible transcript 3
Strand: -
Gene Locus: 12q13.3
External Links:

DDIT3 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate DDIT3   
T(co)Fs that Repress DDIT3
The Intensity of the Gene Regulated by T(co)Fs:
DDIT3-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
DDIT3 IRF6 shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 1.66716 0.73739 0.00074 0.01609 DataSet_01_101
DDIT3 MYB shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 1.79574 0.84458 4.14509e-08 1.16916e-06 DataSet_01_102
DDIT3 ESRRA shRNA Colon HCT116 0.64531 -0.63194 0.08999 0.84512 DataSet_01_115
DDIT3 ID1 siRNA Lung A549 1.9794 0.98506 0.02675 0.18936 DataSet_01_117
DDIT3 ZIC2 siRNA Pancreas PANC1 17.9255 4.16394 - - DataSet_01_121
DDIT3 FOXM1 siRNA Central_nervous_system U87 6.24756 2.64329 - - DataSet_01_122
DDIT3 ZNF708 siRNA Gastrointestinal_tissue GIST-T1 0.60391 -0.72759 0.00015 0.00625 DataSet_01_130
DDIT3 SPDEF shRNA Mammary_gland MCF7 1.95571 0.96769 5.77272e-05 0.01101 DataSet_01_135
DDIT3 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 13.2161 3.72423 2.08762e-09 1.57029e-06 DataSet_01_137
DDIT3 IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.79524 0.84418 0.1202 0.99993 DataSet_01_138
DDIT3 POLR3A siRNA Mammary_gland MCF7 2.39553 1.26034 - - DataSet_01_139
DDIT3 SOX4 shRNA Parotid_gland ACC3 2.61572 1.38721 0.01965 0.92718 DataSet_01_140
DDIT3 SF1 siRNA Adrenal_gland H295R/TR 0.56531 -0.82288 4.13388e-06 0.00031 DataSet_01_146
DDIT3 TEAD4 shRNA Stomach SNU216 0.57507 -0.79818 - - DataSet_01_151
DDIT3 TAL1 shRNA Umbilical_cord_blood ECFCs 3.78801 1.92144 5.2867e-05 0.12155 DataSet_01_152
DDIT3 STAT1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.76163 0.81691 0.00265 0.07055 DataSet_01_154
DDIT3 GATA3 siRNA Peripheral_blood CD4+ T cells 472.365 8.88376 0.08012 0.41493 DataSet_01_163
DDIT3 JUN siRNA Peripheral_blood CD4+ T cells 0.55002 -0.86245 0.10576 0.30024 DataSet_01_164
DDIT3 MAF siRNA Peripheral_blood CD4+ T cells 0.59966 -0.73778 0.17563 0.50576 DataSet_01_165
DDIT3 NFATC3 siRNA Peripheral_blood CD4+ T cells 0.56835 -0.81514 0.1267 0.37489 DataSet_01_166
DDIT3 STAT3 siRNA Peripheral_blood CD4+ T cells 0.56953 -0.81216 0.12628 0.99183 DataSet_01_168
DDIT3 NR4A1 siRNA Pancreas PANC1 2.11893 1.08333 2.90378e-06 0.00042 DataSet_01_174
DDIT3 TCF4 siRNA Autonomic_ganglia SH-SY5Y 5.05455 2.33758 0.11434 0.27848 DataSet_01_185
DDIT3 SPDEF siRNA Mammary_gland MCF7 1.78426 0.83532 2.37176e-05 0.03655 DataSet_01_189
DDIT3 AR siRNA Prostate R1-D567 1.72556 0.78707 0.01008 0.2097 DataSet_01_192
DDIT3 CREB1 shRNA Parotid_gland H3118 MEC 0.53412 -0.90476 0.30285 0.66062 DataSet_01_194
DDIT3 CREB1 shRNA Parotid_gland HSY 0.60149 -0.73339 0.19612 0.86953 DataSet_01_195
DDIT3 TP63 siRNA Head_and_neck SCC-012 0.65172 -0.61768 - - DataSet_01_201
DDIT3 XBP1 shRNA Mammary_gland MDA-MB-231 0.40932 -1.28869 0.00038 0.01047 DataSet_01_204
DDIT3 KLF3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.63973 -0.64446 3.21241e-06 9.95432e-05 DataSet_01_221
DDIT3 FOXM1 siRNA Mammary_gland MCF7 1.741 0.79992 0.01604 0.38882 DataSet_01_223
DDIT3 KLF2 shRNA Bone_marrow RPMI8226 0.48879 -1.0327 0.00718 0.44058 DataSet_01_226
DDIT3 IRX1 shRNA Bone_marrow 143B 1.57029 0.65103 0.00661 0.08879 DataSet_01_227
DDIT3 FOXA1 siRNA Prostate LNCaP 0.50859 -0.97542 0.10195 0.3918 DataSet_01_233
DDIT3 FOXP1 siRNA Prostate LNCaP 0.13106 -2.93174 3e-04 0.09798 DataSet_01_234
DDIT3 STAT5 shRNA Haematopoietic_and_lymphoid_tissue K562 0.35751 -1.48394 4.68549e-06 0.00034 DataSet_01_239
DDIT3 YBX1 shRNA Mammary_gland MDA 1.83935 0.87919 4.91306e-08 2.31294e-06 DataSet_01_255
DDIT3 YBX1 shRNA Mammary_gland MDA 5.09858 2.3501 0.00163 0.01322 DataSet_01_257
DDIT3 YBX1 shRNA Mammary_gland MDA 0.57324 -0.80279 0.01077 0.11591 DataSet_01_258
DDIT3 YBX1 shRNA Mammary_gland MDA 0.63717 -0.65024 0.00137 0.00761 DataSet_01_259
DDIT3 IRF4 shRNA Lymph BL2 1.818 0.86235 - - DataSet_01_262
DDIT3 TLX1 shRNA Haematopoietic_and_lymphoid_tissue ALLSIL 0.61022 -0.7126 0.15447 0.99999 DataSet_01_263
DDIT3 SIX4 siRNA Ovary PEO1 0.56221 -0.83081 0.005 0.04234 DataSet_01_269
DDIT3 AR shRNA Prostate CWR22Pc 3.96641 1.98783 3.90597e-05 0.00397 DataSet_01_278
DDIT3 STAT5 shRNA Prostate CWR22Pc 1.74187 0.80064 0.00499 0.03526 DataSet_01_279
DDIT3 MSX1 siRNA Tooth Dental Pulp Cells 4.54523 2.18435 1.50811e-06 9.23417e-05 DataSet_01_281
DDIT3 AHR siRNA Haematopoietic_and_lymphoid_tissue THP-1 1.53979 0.62274 2.71523e-06 0.00015 DataSet_01_283
DDIT3 ZIC5 siRNA Skin A375 6.98482 2.80422 - - DataSet_01_284
DDIT3 ZIC5 siRNA Skin SK-MEL-28 1.64972 0.72222 - - DataSet_01_285
DDIT3 TP53 shRNA Haematopoietic_and_lymphoid_tissue JVM2 1.52625 0.60999 3.22575e-05 0.00048 DataSet_01_286
DDIT3 POSTN shRNA Brain GSC272 2.07001 1.04964 0.12336 0.55804 DataSet_01_293
DDIT3 RELB siRNA Lung A549 1.51109 0.59559 0.04673 0.24284 DataSet_01_294
DDIT3 TFAP4 siRNA Brain BE(2)-C 0.20166 -2.31001 0.35713 0.51625 DataSet_01_295
DDIT3 PTEN shRNA Skin A431 1.56539 0.64652 0.01499 0.10959 DataSet_01_301
DDIT3 ARNT siRNA Upper_aerodigestive_tract HSC3 1.51087 0.59538 - - DataSet_01_315
DDIT3 ERG siRNA Cervix HeLa 3.19103 1.67402 6.19156e-07 5.28556e-06 DataSet_01_316
DDIT3 ZNF25 siRNA Bone_marrow hMSC-TERT4 0.40441 -1.30609 0.02948 0.42684 DataSet_01_319
DDIT3 MYC siRNA Colon HCT116 1.54957 0.63187 0.00015 0.00063 DataSet_01_324
DDIT3 TOX shRNA Haematopoietic_and_lymphoid_tissue CCRF-CEM 0.55065 -0.86078 0.27578 0.66957 DataSet_01_331
DDIT3 GATA3 siRNA Oral_cavity OEC-M1 1.62727 0.70246 0.15841 0.99787 DataSet_01_347
DDIT3 ETV4 shRNA Prostate PC3 2.10126 1.07126 - - DataSet_01_356
DDIT3 CDX2 siRNA Colon COLO320 1.86209 0.89692 - - DataSet_01_357
DDIT3 PAX3 shRNA Soft_tissue Rh30 2.80095 1.48592 - - DataSet_01_359
DDIT3 GTF2B siRNA Cervix HeLa 1.74582 0.80391 - - DataSet_01_362
DDIT3 RBM17 shRNA Liver HepG2 0.64806 -0.62579 0.10763 0.3697 DataSet_02_100
DDIT3 TAF15 shRNA Liver HepG2 1.70912 0.77326 0.00148 0.01237 DataSet_02_106
DDIT3 SSB shRNA Liver HepG2 1.5853 0.66476 0.00883 0.02463 DataSet_02_107
DDIT3 RBM39 shRNA Liver HepG2 0.47878 -1.06256 0.01786 0.21151 DataSet_02_111
DDIT3 U2AF2 shRNA Liver HepG2 0.54751 -0.86904 0.04184 0.12998 DataSet_02_113
DDIT3 SUB1 shRNA Liver HepG2 1.63101 0.70576 0.0136 0.14285 DataSet_02_117
DDIT3 PTBP1 shRNA Liver HepG2 0.5695 -0.81222 0.00178 0.00862 DataSet_02_120
DDIT3 PCBP2 shRNA Liver HepG2 1.55869 0.64034 0.00827 0.07213 DataSet_02_123
DDIT3 SRSF3 shRNA Liver HepG2 2.6954 1.4305 0.00219 0.06646 DataSet_02_127
DDIT3 AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.22327 -2.16311 0.001 0.09263 DataSet_02_132
DDIT3 SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 1.56484 0.64602 0.01195 0.2296 DataSet_02_133
DDIT3 RBM17 shRNA Haematopoietic_and_lymphoid_tissue K562 1.66954 0.73945 0.00822 0.24572 DataSet_02_138
DDIT3 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.61997 -0.68972 0.01139 0.03992 DataSet_02_143
DDIT3 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.77488 0.82772 0.00903 0.19832 DataSet_02_144
DDIT3 SAFB2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.64208 -0.63918 0.00699 0.41496 DataSet_02_150
DDIT3 PSIP1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.83434 0.87526 0.00742 0.0795 DataSet_02_158
DDIT3 AGO1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.54487 0.62749 0.02202 0.53443 DataSet_02_162
DDIT3 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.34233 -1.54653 0.351 0.56941 DataSet_02_163
DDIT3 SSB shRNA Haematopoietic_and_lymphoid_tissue K562 1.98865 0.99179 0.00171 0.20269 DataSet_02_164
DDIT3 ZFX siRNA Prostate C4-2B 1.78708 0.83761 0.00013 0.00192 DataSet_02_172
DDIT3 ZFX siRNA Mammary_gland MCF7 1.58398 0.66356 8.0785e-05 0.01771 DataSet_02_206
DDIT3 AR siRNA Prostate abl cells 0.539068 -0.891462 0.112138639782413 0.999852161656754 DataSet_03_004
DDIT3 AR siRNA Prostate LNCaP 0.468295 -1.09451 0.132719780019992 1 DataSet_03_005
DDIT3 ARID2 CRISPR Liver JHH4 1.77073 0.824344 0.164891245078095 1 DataSet_03_015
DDIT3 ATF4 siRNA Skin A375 0.632618 -0.660592 0.26572467527557 0.775512819201899 DataSet_03_018
DDIT3 E2F7 siRNA Upper_aerodigestive_tract SCC25 1.59792 0.676194 4.22927245318945e-05 0.000573629270405155 DataSet_03_063
DDIT3 ESR1 siRNA Mammary_gland MCF7 1.77083 0.824426 0.392845516372784 0.422407856795939 DataSet_03_071
DDIT3 FOXA1 siRNA Mammary_gland MCF7 2.53426 1.34156 4.02027394542123e-07 3.75068595654096e-05 DataSet_03_080
DDIT3 FOXA1 siRNA Mammary_gland MCF7 2.72717 1.4474 1.68268279791454e-15 9.3909984150708e-13 DataSet_03_081
DDIT3 FOXA1 siRNA Mammary_gland MCF7 2.72717 1.4474 1.68268279791454e-15 9.3909984150708e-13 DataSet_03_082
DDIT3 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 0.64256 -0.638097 - - DataSet_03_096
DDIT3 GATA2 siRNA Uterus Decidual stromal cells 1.82065 0.864456 0.270099596033264 0.849182725091072 DataSet_03_100
DDIT3 GATA3 siRNA Mammary_gland MCF7 4.90795 2.29512 0.0463416184654883 0.17415178046924 DataSet_03_103
DDIT3 GFP siRNA Upper_aerodigestive_tract SCC25 1.54118 0.624034 3.29815033582355e-05 0.000934043443069443 DataSet_03_112
DDIT3 HMGA2 siRNA Mammary_gland MDA-MB-231 0.464868 -1.10511 0.00725878960086076 0.505785671673658 DataSet_03_125
DDIT3 KDM3A siRNA Mammary_gland MCF7 2.14268 1.09941 0.00404873354480777 0.0491314311310111 DataSet_03_146
DDIT3 Klf4 siRNA Skin Primary neonatal keratinocytes 0.491791 -1.02388 0.00937916988971593 0.0423348941684587 DataSet_03_147
DDIT3 MEF2D shRNA Liver HuH7 2.78342 1.47686 - - DataSet_03_162
DDIT3 MEF2D siRNA Liver HuH7 6.33646 2.66368 - - DataSet_03_163
DDIT3 MITF siRNA Skin SK-MEL-5 0.46815 -1.09496 3.29225914222088e-06 3.92822624344061e-05 DataSet_03_168
DDIT3 MYB siRNA Cord_Blood CD34+ progenitor cells 2.2694 1.18231 - - DataSet_03_170
DDIT3 MYCN CRISPR Neuroblastoma CHP-134 0.488198 -1.03446 1.91886771171171e-07 4.39694829940798e-05 DataSet_03_183
DDIT3 MYCN CRISPR Neuroblastoma CHP-134 0.488198 -1.03446 1.91886771171171e-07 4.39694829940798e-05 DataSet_03_184
DDIT3 PHB shRNA Embryo Embryonic stem cells (ESCs) 10.9446 3.45215 2.03427379436714e-05 0.000515833712143097 DataSet_03_211
DDIT3 PRRX1 CRISPR Neuroblastoma 691-MES 0.626597 -0.674391 0.379056954332715 0.90928829599233 DataSet_03_217
DDIT3 RELB siRNA Pancreas MIA PaCa-2 0.374415 -1.41729 0.0981752604734981 0.301630740292094 DataSet_03_225
DDIT3 RELB siRNA Immortalized_keratinocyte HaCaT 5.41251 2.4363 1.85129344611909e-09 1.69019672355179e-07 DataSet_03_227
DDIT3 SOX11 siRNA Lung_fibroblast NHLF 0.640318 -0.64314 0.168609438407737 0.576873840310608 DataSet_03_237
DDIT3 SOX11 siRNA Lung_fibroblast NHLF 0.558396 -0.84064 0.0328384718593273 0.278162585783797 DataSet_03_238
DDIT3 SOX2 siRNA Lung LK2 1.86189 0.89677 - - DataSet_03_241
DDIT3 SOX2 CRISPR Seminoma-like TCam-2 0.483217 -1.04926 0.0501076053619916 0.999580851453413 DataSet_03_244
DDIT3 SOX2 siRNA Mammary_gland GSC-11 0.438575 -1.1891 7.01812354706844e-07 0.00125699112944631 DataSet_03_245
DDIT3 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 0.576294 -0.795122 - - DataSet_03_246
DDIT3 SOX9 knockdown Liver HepG2 0.286081 -1.8055 5.29370085628375e-08 3.87702506559058e-05 DataSet_03_248
DDIT3 STAT3 CRISPR Embryo hESC 0.254811 -1.9725 0.00492645698248963 0.048936139359397 DataSet_03_258
DDIT3 TBX3 siRNA Skin Fibroblast 1.70444 0.769295 4.22431061122274e-05 0.00262735850431082 DataSet_03_265
DDIT3 TET2 siRNA Prostate DU145 1.75549 0.81187 - - DataSet_03_271
DDIT3 TFAP2C siRNA Mammary_gland MCF7 1.55579 0.637645 0.0621784756632428 0.39848324666692 DataSet_03_274
DDIT3 TP63 siRNA Skin Primary neonatal keratinocytes 0.112178 -3.15614 8.83259655644064e-06 0.00116196627656996 DataSet_03_281
DDIT3 ZNF746 siRNA Colon HCT116 0.545632 -0.874 - - DataSet_03_293
DDIT3 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 1.67288 0.74233 0.00895763747810263 0.423353473090641 DataSet_04_001
DDIT3 MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.525855 -0.927263 0.00439335507956593 0.0188662054499614 DataSet_04_012
DDIT3 NUP35 shRNA Haematopoietic_and_lymphoid_tissue K562 0.661251 -0.59673 0.0124298170289432 0.0368197199572888 DataSet_04_015
DDIT3 SMAD4 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.09655 1.06802 0.00162289713367725 0.0979887211869635 DataSet_04_019
DDIT3 ACTN4 CRISPR Liver HepG2 1.70411 0.769018 0.0129995603776107 0.0644535864851995 DataSet_04_042
DDIT3 CNOT7 shRNA Liver HepG2 0.527276 -0.92337 0.00968091779672482 0.0282810361904741 DataSet_04_051
DDIT3 YBX3 shRNA Liver HepG2 1.7958 0.844626 0.000477145037065525 0.0334995062512868 DataSet_02_98
DDIT3 NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.84106 0.880539 0.000316206294589548 0.0350786864067032 DataSet_04_046
DDIT3 CCAR1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.519024 -0.946127 0.00240419850731816 0.042566034251948 DataSet_04_064
DDIT3 DDX1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.460415 -1.11899 0.00499726161618091 0.374619201786221 DataSet_04_063
DDIT3 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 0.448846 -1.15571 0.000256446545444746 0.00406454836181464 DataSet_04_059
DDIT3 PRPF6 shRNA Haematopoietic_and_lymphoid_tissue K562 0.500296 -0.999146 0.0826467244199569 0.421191057648026 DataSet_04_065
DDIT3 TET1 siRNA Lung H1299 2.23452 1.15996 - - DataSet_03_319
DDIT3 TET1 siRNA Lung H1299 2.23452 1.15996 - - DataSet_03_321
DDIT3 NFKBIZ knockout Colon Colon organoid 0.452328 -1.14456 2.138233e-04 0.181314760 DataSet_03_323
DDIT3 SMARCA4 siRNA Colon HCT116 1.53164 0.615079 2.440568e-01 9.892536e-01 DataSet_03_301
DDIT3 SMARCA4 siRNA Colon HCT116 1.51125 0.595747 1.664140e-02 0.1505706 DataSet_03_302
DDIT3 NSD2 shRNA Haematopoietic_and_lymphoid_tissue K562 3.46148 1.79139 1.570799e-10 3.230874e-07 DataSet_03_303
DDIT3 ELF3 CRISPR Bile_duct HBDEC2 0.599206 -0.738875 7.773049e-04 5.091630e-03 DataSet_03_304
DDIT3 HDAC5 siRNA Liver human hepatocytes 0.462204 -1.1134 3.187974e-06 2.123975e-04 DataSet_03_346
DDIT3 SNAI2 shRNA Pancreas KLM1 2.46479 1.30146 1.565919e-03 0.10737635 DataSet_03_307
DDIT3 PRMT1 shRNA Lung A549 0.164614 -2.60284 - - DataSet_03_342
DDIT3 INO80 siRNA Muscle RD 1.9213 0.94208 - - DataSet_03_344
DDIT3 BRCA1 siRNA Mammary_gland MCF7 1.52895 0.612537 4.326210e-02 0.9999931 DataSet_03_308
DDIT3 LITAF siRNA Lymph KARPAS-231 0.647879 -0.626203 2.205956e-01 0.62606687 DataSet_03_309
DDIT3 LITAF siRNA Lymph VAL 0.474142 -1.07661 2.265227e-01 0.692665754 DataSet_03_310
DDIT3 EZH2 shRNA Mammary_gland MCF7 0.495831 -1.01208 4.812836e-05 3.012693e-03 DataSet_03_331
DDIT3 EZH2 knockdown Colon HCT116 0.350716 -1.51162 0.109038023 0.8488990 DataSet_03_334
DDIT3 BCL3 siRNA Central_nervous_system U87 0.652926 -0.615008 1.475987e-06 1.225219e-04 DataSet_03_336
DDIT3 ARID3B CRISPR Colon HCT15 10.4707 3.38829 - - DataSet_03_335
DDIT3 TET1 CRISPR Mammary_gland MDA-MB-231 1.93589 0.952998 4.117807e-03 3.391027e-02 DataSet_03_347
DDIT3 ZFX siRNA Prostate C4-2B 1.87012 0.903129 1.399943e-06 5.081559e-05 DataSet_03_348
DDIT3 ZFX siRNA Mammary_gland MCF7 1.61286 0.689625 1.439489e-06 3.785855e-04 DataSet_03_349
DDIT3 SKI CRISPR Blood HL60 2.4642 1.30112 1.322555e-02 0.216211847 DataSet_03_351
DDIT3 ESR1 siRNA Mammary_gland MCF7 1.6631 0.733873 1.082376e-03 0.0198329112 DataSet_03_352
DDIT3 ETV5 knockdown Colon HT29 0.345938 -1.53142 2.768741e-02 0.192265588 DataSet_03_353
DDIT3 CREBBP CRISPR Brain U5-NPC 2.47619 1.30812 0.0819962514 0.7490853 DataSet_03_356
DDIT3 TP53 CRISPR Brain U5-NPC 6.87238 2.78081 4.877557e-04 1.499873e-01 DataSet_03_358
DDIT3 MYC siRNA Peripheral_blood T lymphocyte 2.34779 1.2313 3.958338e-06 0.003295486 DataSet_03_363
DDIT3 TP53 knockout Stomach SNU1 0.616825 -0.697066 0.2857294549 0.9301241 DataSet_03_365
DDIT3 USP22 shRNA Liver PLC_PRF_5 cells 0.4375 -1.19265 1.758810e-02 0.14288269 DataSet_03_368
DDIT3 DNMT3A knockout Embryo_kidney HEK293T 45.3252 5.50224 - - DataSet_03_369
DDIT3 ZFP36L1 siRNA Urinary_bladder J82 2.66026 1.41157 - - DataSet_03_371
DDIT3 HNRNPU siRNA Colon RKO 1.81464 0.859687 - - DataSet_03_374
DDIT3 GLI1 siRNA Skeletal_muscle RMS13 1.62619 0.7015 4.712555e-03 0.048550392 DataSet_03_375
DDIT3 ZNF213 siRNA Mammary_gland MCF7 7.8167 2.96656 4.804428e-02 4.221864e-01 DataSet_03_376
DDIT3 SMARCA2 shRNA Lung NCI-H1944 1.53742 0.620512 7.851950e-03 2.073957e-01 DataSet_03_377
DDIT3 DDX5 shRNA Stomach HGC-27 7.86398 2.97526 - - DataSet_03_379
DDIT3 TCF19 CRISPR Oral_squamous CAL27 1.56079 0.642273 6.440205e-06 0.0021778228 DataSet_03_383
DDIT3 YY1 shRNA Brain GSC1517 1.7234 0.785261 - - DataSet_03_384
DDIT3 TRIM8 siRNA Mammary_gland MCF7 2.46292 1.30037 6.443474e-05 0.0033938869 DataSet_03_388
DDIT3 ILF2 siRNA Stomach SGC-7901 3.90141 1.964 0.2531293452 0.44978746 DataSet_03_393
DDIT3 RELA CRISPR Brain T30 0.0472761 -4.40275 0.5076646544 0.8579919 DataSet_03_399
DDIT3 HMGA1 shRNA Bile_duct HUCCT1 2.29646 1.19941 1.028915e-02 0.122986919 DataSet_03_400
DDIT3 CDK7 shRNA Bone_marrow D458 3.64626 1.86642 8.224661e-03 0.15736303 DataSet_03_404
DDIT3 SIRT1 siRNA Pancreas PANC1 0.592163 -0.755934 1.428188e-03 0.020973806 DataSet_03_410
DDIT3 USP22 shRNA Liver HuH7 2.47779 1.30906 - - DataSet_03_411
DDIT3 RUNX2 shRNA Cord_blood Natural Killer Cell 0.467925 -1.09565 2.151497e-01 0.793390621 DataSet_03_416
DDIT3 MAEL CRISPR Liver Alexander cells 0.215686 -2.21299 - - DataSet_03_423
DDIT3 STAT5B CRISPR Embryo_kidney HEK293 1.56655 0.647593 6.780511e-03 0.334609313 DataSet_03_424
DDIT3 USP7 shRNA Skin xenograft cells 0.445103 -1.16779 0.26708053 0.4348960 DataSet_03_431
DDIT3 SUFU shRNA Mammary_gland HCC1954 cells 2.35758 1.2373 0.6844411580 0.8892066 DataSet_03_437
DDIT3 SETDB1 shRNA Colon HCT116 7.8239 2.96789 - - DataSet_03_440
DDIT3 PURA siRNA Cervix HeLa 0.433605 -1.20555 1.813567e-04 0.031308934 DataSet_03_444
DDIT3 CBX2 siRNA Mammary_gland MDA-MB-231 1.5005 0.585446 3.742777e-02 1.220662e-01 DataSet_03_450
DDIT3 CBX2 siRNA Mammary_gland MCF7 3.19554 1.67606 3.490217e-02 0.0817082061 DataSet_03_451
DDIT3 SMARCA2 shRNA Lung HCC2302 0.626695 -0.674164 2.955086e-05 5.783777e-05 DataSet_03_455
DDIT3 ARID1A shRNA Bile_duct MMNK1 1.73216 0.792571 2.527872e-03 0.046651502 DataSet_03_458
DDIT3 TXNIP shRNA Cord_blood ST3 1.97183 0.979536 8.447926e-02 0.3576078175 DataSet_03_462
DDIT3 PARP1 knockout Embryo_kidney HEK293a 2.21475 1.14714 9.805847e-07 1.389081e-05 DataSet_03_464
DDIT3 STAT3 shRNA Liver HepG2 1.64017 0.713843 3.251972e-02 0.2891434573 DataSet_03_465
DDIT3 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 5.38202 2.42815 - - DataSet_03_467
DDIT3 SMARCA1 shRNA Embryo_kidney HEK293T 0.651685 -0.617752 - - DataSet_03_468
DDIT3 LIN28A siRNA Mammary_gland MCF7M 1.58576 0.665172 5.519937e-02 0.3358400 DataSet_03_469
DDIT3 LIN28A siRNA Mammary_gland MCF7M 1.58576 0.665172 5.519937e-02 0.3358400 DataSet_03_470
DDIT3 EZH2 siRNA Prostate LNCaP 0.575434 -0.797279 - - DataSet_03_472
DDIT3 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 1.67288 0.74233 0.002873213 0.3407931 DataSet_04_072
Regulation Region
 
T(co)Fs that significantly regulate SOX2 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of DDIT3
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines