Gene Overview
Target Gene: INHBA
NCBI Official Symbol: INHBA
Entrez ID: 3624
Ensembl ID: ENSG00000122641
Gene Full Name: inhibin subunit beta A
Strand: -
Gene Locus: 7p14.1
External Links:

INHBA Significantly Regulated by These T(co)Fs

T(co)Fs that Activate INHBA   
T(co)Fs that Repress INHBA
The Intensity of the Gene Regulated by T(co)Fs:
INHBA-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
INHBA HNF1B shRNA Ovary RMG2 1.50527 0.59002 0.01147 0.02887 DataSet_01_103
INHBA SPDEF shRNA Mammary_gland MCF7 2.76865 1.46918 0.48295 0.99999 DataSet_01_107
INHBA HOXA1 siRNA Lung_fibroblast IMR-90 2.56606 1.35955 0.00104 0.03304 DataSet_01_110
INHBA TCF3 shRNA Mammary_gland MDA-MB468 5.49902 2.45917 3.14212e-05 0.00109 DataSet_01_116
INHBA ID1 siRNA Lung A549 4.9333 2.30255 0.0732 0.27616 DataSet_01_117
INHBA ZIC2 siRNA Pancreas PANC1 2.10082 1.07095 - - DataSet_01_121
INHBA FOXM1 siRNA Central_nervous_system U87 12.0299 3.58856 - - DataSet_01_122
INHBA IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.63436 0.70873 0.2205 0.99993 DataSet_01_138
INHBA POLR3A siRNA Mammary_gland MCF7 2.03186 1.0228 - - DataSet_01_139
INHBA SOX4 shRNA Parotid_gland ACC3 1.66015 0.73131 0.10339 0.94842 DataSet_01_140
INHBA NR3C1 siRNA Uterus Endometrial stromal cells 1.70232 0.7675 0.57439 0.99972 DataSet_01_141
INHBA ELK1 siRNA Peripheral_blood CD4+ T cells 2.89051 1.53132 0.00055 0.00726 DataSet_01_162
INHBA GATA3 siRNA Peripheral_blood CD4+ T cells 0.23003 -2.12009 0.00011 0.02344 DataSet_01_163
INHBA JUN siRNA Peripheral_blood CD4+ T cells 3.85186 1.94555 7.29643e-05 0.00312 DataSet_01_164
INHBA MAF siRNA Peripheral_blood CD4+ T cells 3.16173 1.66071 0.00022 0.00964 DataSet_01_165
INHBA NFATC3 siRNA Peripheral_blood CD4+ T cells 1853.91 10.8564 0.01398 0.11057 DataSet_01_166
INHBA NFKB1 siRNA Peripheral_blood CD4+ T cells 0.33322 -1.58546 0.00143 0.10329 DataSet_01_167
INHBA FOSL1 siRNA Mammary_gland BT549 3.04358 1.60577 9.97235e-14 1.49984e-10 DataSet_01_171
INHBA JUN siRNA Mammary_gland BT549 2.13798 1.09625 6.14495e-06 0.00156 DataSet_01_172
INHBA TCF4 siRNA Autonomic_ganglia SH-SY5Y 0.42804 -1.22418 1.3772e-05 0.0042 DataSet_01_185
INHBA CREB1 shRNA Parotid_gland H3118 MEC 2.55819 1.35512 0.62877 0.85423 DataSet_01_194
INHBA TP63 siRNA Immortalized_keratinocyte HaCaT RG 2.14462 1.10072 - - DataSet_01_196
INHBA TP63 siRNA Immortalized_keratinocyte HaCaT RG 1.96288 0.97297 - - DataSet_01_197
INHBA TP63 siRNA Head_and_neck SCC-1 0.22998 -2.1204 - - DataSet_01_198
INHBA TP63 siRNA Head_and_neck SCC-1 0.60657 -0.72125 - - DataSet_01_199
INHBA XBP1 shRNA Mammary_gland MDA-MB-231 1.97441 0.98142 0.00183 0.02464 DataSet_01_204
INHBA HIC1 shRNA Mammary_gland HBL100 2.40302 1.26485 - - DataSet_01_205
INHBA MITF shRNA Skin COLO829 3.48899 1.80281 0.1641 0.3677 DataSet_01_207
INHBA FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 0.2487 -2.0075 - - DataSet_01_209
INHBA FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.63199 -0.66203 - - DataSet_01_210
INHBA REST siRNA Prostate LNCaP 0.61786 -0.69465 0.12036 0.38852 DataSet_01_211
INHBA EGR3 shRNA Prostate M12 0.37527 -1.414 1.22626e-06 0.00157 DataSet_01_212
INHBA LIN28A siRNA Embryo H9 7.25359 2.8587 2.01931e-06 0.00036 DataSet_01_215
INHBA SNAI2 shRNA Skin Primary human keratinocytes 0.43335 -1.20639 0.00747 0.03968 DataSet_01_225
INHBA IRX1 shRNA Bone_marrow 143B 1.52579 0.60956 0.00484 0.07602 DataSet_01_227
INHBA ESR2 siRNA Mammary_gland BT549 3.50642 1.81 5.61951e-09 4.39513e-06 DataSet_01_229
INHBA JUN shRNA Soft_tissue LP6 0.43257 -1.20898 4.95883e-06 0.04227 DataSet_01_230
INHBA TWIST1 shRNA Stomach CAF32 0.44972 -1.1529 0.00113 0.02033 DataSet_01_253
INHBA TWIST1 shRNA Stomach CAF 0.59181 -0.7568 0.09327 0.58529 DataSet_01_254
INHBA ESRRA shRNA Embryo_kidney 293T 2.44299 1.28865 0.00787 0.53183 DataSet_01_280
INHBA ZIC5 siRNA Skin A375 2.96827 1.56962 - - DataSet_01_284
INHBA SP3 siRNA Haematopoietic_and_lymphoid_tissue JURKAT 0.5107 -0.96944 0.02734 0.78856 DataSet_01_290
INHBA POSTN shRNA Brain GSC272 1.89251 0.9203 0.19696 0.59805 DataSet_01_293
INHBA TFAP4 siRNA Brain BE(2)-C 0.27431 -1.86614 0.44557 0.51625 DataSet_01_295
INHBA SOX7 siRNA Umbilical_vein HUVEC 1.8927 0.92044 0.08091 0.89788 DataSet_01_299
INHBA SOX17 siRNA Umbilical_vein HUVEC 1.51529 0.5996 0.27298 0.99998 DataSet_01_300
INHBA PTEN shRNA Skin A431 0.29669 -1.753 0.07135 0.22024 DataSet_01_301
INHBA PTEN shRNA Mammary_gland SKBR3 1.54253 0.6253 0.07681 0.59678 DataSet_01_303
INHBA BRD4 siRNA Ovary Ovcar8 0.49367 -1.01837 0.00025 0.00335 DataSet_01_311
INHBA ELK3 shRNA Mammary_gland MDA-MB-231 0.63436 -0.65662 0.00469 0.012 DataSet_01_318
INHBA MYC siRNA Colon HCT116 4.00506 2.00182 1.58332e-09 4.98113e-08 DataSet_01_324
INHBA TP63 shRNA Immortalized_keratinocyte HaCaT 3.72376 1.89676 1.66762e-11 6.01244e-08 DataSet_01_325
INHBA TP63 shRNA Immortalized_keratinocyte HaCaT 3.72376 1.89676 1.66762e-11 6.01244e-08 DataSet_01_328
INHBA STAT3 siRNA Liver LX-2 1.9923 0.99443 1.53045e-06 4.04862e-05 DataSet_01_334
INHBA KLF7 siRNA Embryo HCE 0.66089 -0.59753 0.22188 0.64704 DataSet_01_340
INHBA ZNF24 siRNA Embryo_kidney HEK293 1.88094 0.91145 - - DataSet_01_353
INHBA SOX17 siRNA Umbilical_vein HUVEC 2.97715 1.57393 - - DataSet_01_360
INHBA AR siRNA Prostate LNCaP 3.12234 1.64263 0.0522980453782848 1 DataSet_03_005
INHBA ASCL1 siRNA Lung DMS79 1.51219 0.596644 0.534909276159272 0.915108027212981 DataSet_03_016
INHBA BCL6 siRNA Mammary_gland MCF7 1.74718 0.805026 0.00616770659497086 0.989541443114508 DataSet_03_024
INHBA CEBPB siRNA Embryo hESC 3.42801 1.77737 0.0498467604465368 0.370120135873034 DataSet_03_049
INHBA FOXM1 siRNA Aorta Vascular smooth muscle cells 1.8514 0.888617 - - DataSet_03_090
INHBA GATA4 siRNA Stomach AGS 1.95659 0.968339 0.0627062132296628 0.699790914655457 DataSet_03_105
INHBA GATA4 siRNA Stomach YCC3 2.39989 1.26297 0.0594659490214546 0.603425978782528 DataSet_03_107
INHBA GRHL3 siRNA Skin Primary neonatal keratinocytes 0.631013 -0.664259 0.0704302585169786 0.317938802102502 DataSet_03_113
INHBA HNF4a siRNA Liver HepG2 0.485507 -1.04244 0.0590277242923674 0.653511729299769 DataSet_03_126
INHBA JUN siRNA Fibroblasts WI38 1.55563 0.6375 0.000339210545599093 0.00783612066707125 DataSet_03_140
INHBA JUN siRNA Fibroblasts WI38 1.55563 0.6375 0.000338782656593845 0.00778302910333763 DataSet_03_141
INHBA Klf4 siRNA Skin Primary neonatal keratinocytes 0.358257 -1.48093 1.57136307125859e-05 0.000838124810544452 DataSet_03_147
INHBA KLF5 siRNA Colon SW480 1.51822 0.602384 0.00117214894166898 0.0769592714881409 DataSet_03_148
INHBA KLF5 siRNA Stomach AGS 1.68171 0.749926 0.154681257908738 0.639454192266346 DataSet_03_149
INHBA KLF5 siRNA Stomach KatoIII 6.83527 2.773 0.00038352953095647 0.0707659945668039 DataSet_03_150
INHBA KLF5 siRNA Stomach YCC3 1.80024 0.848187 0.293330329058209 0.655186417996321 DataSet_03_151
INHBA MEF2D shRNA Liver HuH7 2.62793 1.39393 - - DataSet_03_162
INHBA MITF siRNA Skin Ma-Mel-15 0.524969 -0.929695 0.0461399266863033 0.404348028560161 DataSet_03_166
INHBA MTA2 siRNA Stomach SGC-7901 1.78992 0.839897 - - DataSet_03_169
INHBA MYB siRNA Cord_Blood CD34+ progenitor cells 2.93617 1.55394 - - DataSet_03_170
INHBA MYC siRNA Colon HT29 0.324968 -1.62163 - - DataSet_03_177
INHBA MYC siRNA Central_nervous_system DAOY M2.1 13.055 3.70653 1.80935811794121e-09 1.83951408657356e-07 DataSet_03_178
INHBA PHB shRNA Embryo Embryonic stem cells (ESCs) 2.63721 1.39901 0.00296399427931613 0.0124510758716956 DataSet_03_211
INHBA SOX11 siRNA Lung_fibroblast NHLF 1.50466 0.589436 0.0177569444563023 0.318054959844112 DataSet_03_237
INHBA SOX2 siRNA Mammary_gland GSC-11 0.496143 -1.01117 4.20281599873842e-06 0.00180279217081826 DataSet_03_245
INHBA SP1 siRNA Mammary_gland MDA-MB-231 0.258781 -1.95019 0.128851206101924 0.413972819854456 DataSet_03_250
INHBA STAT3 CRISPR Embryo hESC 0.423768 -1.23865 0.0932931302358488 0.178480235260809 DataSet_03_258
INHBA STAT6 siRNA Umbilical_vein HUVEC 0.570529 -0.809629 0.850834766111591 0.982358112279984 DataSet_03_264
INHBA TFAP2C siRNA Mammary_gland MCF7 8.16326 3.02915 0.00104131038789926 0.172108961129215 DataSet_03_274
INHBA TP53 siRNA Foreskin Neonatal foreskin keratinocytes 1.6453 0.718353 0.0458271737502397 0.999791649573014 DataSet_03_278
INHBA TP63 siRNA Skin Primary neonatal keratinocytes 0.567085 -0.818363 0.0043685893930408 0.0272633579105938 DataSet_03_281
INHBA ZNF165 siRNA Mammary_gland SUM159 5.48227 2.45477 0.00141211360454803 0.999998167536832 DataSet_03_288
INHBA ZNF750 siRNA Skin Primary neonatal keratinocytes 0.530565 -0.914398 0.00369968316001508 0.0502298676050951 DataSet_03_294
INHBA CNOT3 shRNA Lung A549 1.64949 0.72202 2.894397e-01 0.8890710 DataSet_03_340
INHBA EZH2 shRNA Colon SW480 1.64541 0.718449 - - DataSet_03_298
INHBA SNAI2 shRNA Pancreas KLM1 0.255348 -1.96946 4.999739e-02 0.30547028 DataSet_03_307
INHBA INO80 siRNA Muscle RD 4.23891 2.08369 - - DataSet_03_344
INHBA TET1 CRISPR Mammary_gland MDA-MB-231 47.5896 5.57258 4.679360e-02 1.638590e-01 DataSet_03_347
INHBA EZH2 shRNA Mammary_gland LM2 1.83194 0.873375 6.395053e-04 4.893136e-02 DataSet_03_350
INHBA SKI CRISPR Blood HL60 3 1.58496 1.448824e-01 0.530710778 DataSet_03_351
INHBA RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 1.59588 0.674353 3.001276e-01 5.419885e-01 DataSet_03_359
INHBA ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 2.6686 1.41608 1.703663e-01 2.597342e-01 DataSet_03_362
INHBA EP300 shRNA Mammary_gland MCF10AT 0.107498 -3.21762 1.492999e-04 0.013321218 DataSet_03_364
INHBA ZNF148 shRNA Mammary_gland MDA-MB-231 0.639118 -0.645846 1.782579e-02 0.097784621 DataSet_03_366
INHBA DNMT3A knockout Embryo_kidney HEK293T 0.276148 -1.85649 - - DataSet_03_369
INHBA TPR shRNA Bone_marrow U2OS 2.31898 1.21349 8.751050e-04 3.428503e-02 DataSet_03_370
INHBA ZFP36L1 siRNA Urinary_bladder J82 2.83098 1.5013 - - DataSet_03_371
INHBA E2F1 siRNA Nasopharynx HK1 0.660377 -0.598637 6.389101e-02 4.172600e-01 DataSet_03_373
INHBA GLI1 siRNA Skeletal_muscle RMS13 3.96883 1.98872 1.049664e-01 0.283527018 DataSet_03_375
INHBA ZNF213 siRNA Mammary_gland MCF7 1.55562 0.637489 6.787266e-01 8.528406e-01 DataSet_03_376
INHBA ZBTB7A siRNA Stomach BGC823 1.51641 0.600662 - - DataSet_03_380
INHBA DNMT1 siRNA Skin Human melanoma cells 3.21049 1.6828 6.500902e-02 1.103640e-01 DataSet_03_382
INHBA TCF19 CRISPR Oral_squamous CAL27 2.71506 1.44099 3.691713e-03 0.0407474681 DataSet_03_383
INHBA TRIM8 siRNA Mammary_gland MCF7 2.2 1.1375 5.961815e-01 0.7541953743 DataSet_03_388
INHBA NFKBIA shRNA Bone_marrow U2OS 0.349379 -1.51714 1.801070e-05 0.04029065 DataSet_03_389
INHBA PRDM15 CRISPR Kidney Immortalized human podocytes 1.63047 0.705287 7.002269e-06 3.499671e-04 DataSet_03_391
INHBA ILF2 siRNA Stomach SGC-7901 6.9 2.7866 0.1955684776 0.38205311 DataSet_03_393
INHBA BMI1 shRNA Bile_duct QBC-939 2.04459 1.03181 8.751669e-01 0.9396104917 DataSet_03_395
INHBA JAZF1 siRNA Cervix HeLa Kyoto 2.33752 1.22498 4.472427e-01 0.852966271 DataSet_03_396
INHBA RELA CRISPR Brain T30 2.87792 1.52503 0.2294365048 0.8400824 DataSet_03_399
INHBA SUMO1 CRISPR Bone_marrow U2OS 0.553559 -0.85319 5.913164e-04 1.008393e-02 DataSet_03_401
INHBA EHF shRNA Stomach MKN7 0.578698 -0.789118 - - DataSet_03_402
INHBA JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 2.54466 1.34747 1.150232e-01 0.3384444 DataSet_03_403
INHBA TFAP2A knockout Embryo H9 0.411765 -1.28011 4.905869e-02 0.14341380 DataSet_03_405
INHBA STRAP knockout Nerve SK-N-AS 0.227254 -2.13762 - - DataSet_03_409
INHBA ZKSCAN3 CRISPR Colon HCT116 0.0701754 -3.83289 5.359092e-03 0.172977533 DataSet_03_415
INHBA RUNX2 shRNA Cord_blood Natural Killer Cell 0.238095 -2.07039 5.256169e-01 0.828936070 DataSet_03_416
INHBA NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 3 1.58496 6.628941e-01 0.771706674 DataSet_03_418
INHBA PRDM1 CRISPR Lymph CD8+ T cells 1.875 0.906891 - - DataSet_03_421
INHBA FOXQ1 CRISPR Lymph Primary CD4+ T cells 2.2 1.1375 - - DataSet_03_422
INHBA STAT5B CRISPR Embryo_kidney HEK293 4.21429 2.07529 7.371475e-02 0.543157489 DataSet_03_424
INHBA FOXP3 CRISPR Peripheral_blood Naive Treg 0.0808823 -3.62803 4.788996e-01 0.772883167 DataSet_03_427
INHBA STAT3 siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 2.96518 1.56812 0.4954836660 1 DataSet_03_430
INHBA USP7 shRNA Skin xenograft cells 0.488854 -1.03252 0.27024232 0.4348960 DataSet_03_431
INHBA PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 1.6 0.678072 - - DataSet_03_432
INHBA POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 2.5 1.32193 4.276818e-01 0.635167284 DataSet_03_434
INHBA EP300 knockout Pancreas HPAF-II orthotopic cells 0.423701 -1.23888 1.802316e-01 3.617111e-01 DataSet_03_436
INHBA SUFU shRNA Mammary_gland HCC1954 cells 1.62592 0.70126 0.5104003568 0.7880076 DataSet_03_437
INHBA FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 2.03717 1.02657 3.398098e-02 0.72689181 DataSet_03_439
INHBA DAXX shRNA Mammary_gland MDA-MB-231 4.27643 2.09641 1.805950e-03 0.05930353 DataSet_03_441
INHBA FOSL1 siRNA Prostate MSKPCa3 0.505456 -0.984343 0.0041908226 0.2168292 DataSet_03_445
INHBA CAMTA1 knockout Embryo_kidney HEK293T 3 1.58496 6.230525e-01 0.73090641 DataSet_03_448
INHBA CBX2 siRNA Mammary_gland MDA-MB-231 3.21302 1.68393 9.575954e-02 2.374239e-01 DataSet_03_450
INHBA CBX2 siRNA Mammary_gland MCF7 5.52892 2.467 3.107113e-05 0.0007934400 DataSet_03_451
INHBA SMARCA2 shRNA Lung HCC2302 0.00935882 -6.73946 3.327619e-17 3.731320e-15 DataSet_03_455
INHBA PPARG siRNA Aortic_valve Valvular endothelial cell 1.64716 0.719981 6.918336e-05 5.903958e-03 DataSet_03_456
INHBA SREBF2 siRNA Umbilical_vein HUVEC 0.26241 -1.9301 1.857153e-01 6.263876e-01 DataSet_03_457
INHBA ARID1A shRNA Bile_duct MMNK1 0.381391 -1.39066 8.151978e-02 0.299136338 DataSet_03_458
INHBA IRF2 shRNA Cord_Blood CD34+ cells 4.24286 2.08504 - - DataSet_03_460
INHBA TXNIP shRNA Cord_Blood CD34+ cells 5.19444 2.37697 - - DataSet_03_461
INHBA TXNIP shRNA Cord_blood ST3 10.75 3.42627 6.148356e-04 0.0465996135 DataSet_03_462
INHBA SOX9 knockout Liver HuH7 2.25 1.16992 6.939181e-01 7.940630e-01 DataSet_03_463
INHBA PARP1 knockout Embryo_kidney HEK293a 2.75383 1.46144 2.769199e-08 7.138796e-07 DataSet_03_464
INHBA SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 1.8 0.847997 - - DataSet_03_467
INHBA SMARCA1 shRNA Embryo_kidney HEK293T 0.6 -0.736966 - - DataSet_03_468
INHBA LIN28A siRNA Mammary_gland MCF7M 6.36337 2.66979 3.228423e-01 0.6983819 DataSet_03_469
INHBA LIN28A siRNA Mammary_gland MCF7M 6.36337 2.66979 3.228423e-01 0.6983819 DataSet_03_470
INHBA WHSC1 siRNA Prostate PC3 1.67461 0.743824 3.381676e-03 0.08075063 DataSet_03_471
INHBA EZH2 siRNA Umbilical_vein HUVEC 0.477799 -1.06552 1.512015e-04 0.031619488 DataSet_03_473
Regulation Region
 
T(co)Fs that significantly regulate MYC by the evidences of both expression and ChIP-seq/motif
Expression Atlas of INHBA
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines