Gene Overview
Target Gene: Klk7
NCBI Official Symbol: Klk7
Entrez ID: 23993
Ensembl ID: ENSMUSG00000030713
Gene Full Name: kallikrein related-peptidase 7 (chymotryptic, stratum corneum)
Strand: +
Gene Locus: 7 B3|7 28.27 cM
External Links:

Klk7 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate Klk7   
T(co)Fs that Repress Klk7
The Intensity of the Gene Regulated by T(co)Fs:
Klk7-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
Klk7 Adnp knockout Embryo Whole embryonic body 2.31915 1.2136 0.353773651303096 0.679748193636039 DataSet_11_001
Klk7 Bcl11a knockout Bone_marrow Bone marrow erythoid progenitors 1.5105 0.595028 0.731445328912463 0.913700904754833 DataSet_11_013
Klk7 Bcl6 knockout Bone_marrow Bone marrow-derived macrophages 0.645799 -0.630843 0.217760468782349 0.594953408996777 DataSet_11_014
Klk7 Dmrt1 knockout Testis Juvenile testes 1.50481 0.589586 0.0167999514332053 0.415961245476151 DataSet_11_025
Klk7 Dmrt1 knockout Testis Juvenile testes 0.58239 -0.779943 0.0191966624133121 0.932139260123802 DataSet_11_026
Klk7 Foxp1 knockout Eye Lens 0.424242 -1.23704 - - DataSet_11_044
Klk7 Gata4 knockout Intestine Jejunum 1.89896 0.925211 0.137461437572915 0.639114027505005 DataSet_11_049
Klk7 Hsf4 knockout Eye Lens 0.243272 -2.03936 0.421932477400562 0.987999303842427 DataSet_11_058
Klk7 Irf6 knockout Skin Skin 0.190277 -2.39383 1.28986998615611e-05 0.00581591160497041 DataSet_11_062
Klk7 Nhlh2 knockout Eye Retina 0.135593 -2.88264 0.0161082016345304 0.523726874680013 DataSet_11_092
Klk7 Nr2f2 knockout Ovary E16.5 Ovary 0.588733 -0.764314 0.0271848929660912 0.355623836773605 DataSet_11_095
Klk7 p63 siRNA Skin Primary keratinocytes 2.66791 1.41571 0.000297575824154538 0.00469650546103217 DataSet_11_099
Klk7 Plagl2 knockout Intestine Small intestine 1.88679 0.915936 0.347280265412787 0.650382374494755 DataSet_11_104
Klk7 Prox1 knockout Liver Liver 5.04752 2.33557 - - DataSet_11_109
Klk7 Rest knockout Brain Brain 3.02083 1.59495 0.124125530750545 1 DataSet_11_113
Klk7 Runx1 knockout Mammary_gland Luminal epithelial cells 1.63399 0.7084 0.12643599672667 0.999784944667092 DataSet_11_117
Klk7 Smad4 siRNA Brain bEnd3 0.129673 -2.94705 - - DataSet_11_127
Klk7 Smad4 knockout Aorta Aortic arteries 0.441355 -1.17999 0.274629967369249 0.690983522507515 DataSet_11_128
Klk7 Sox11 knockout Eye Retina 0.454545 -1.1375 - - DataSet_11_137
Klk7 Sox2 siRNA Embryo NG4 3.39519 1.76349 0.00220435974815708 0.0506610704396297 DataSet_11_141
Klk7 Sp3 knockout Heart Heart 3.41567 1.77217 0.209584650073975 0.781742683752722 DataSet_11_145
Klk7 Spdef knockout Colon Colon 0.515214 -0.956757 0.924116681016883 0.998614723164469 DataSet_11_146
Klk7 Spdef knockout Stomach Stomach 0.245233 -2.02777 0.113634698833092 0.871950375651701 DataSet_11_147
Klk7 Stat3 knockout Lung Lung typeII cells 0.510176 -0.970934 0.370882936383281 0.830187195524234 DataSet_11_151
Klk7 Stat4 knockout Lymph Lamina propria lymphocytes 2.87639 1.52426 0.243408516778618 0.924261066168849 DataSet_11_152
Klk7 Tbx1 knockout Ear Otic vesicles 1.76468 0.819407 0.286629936247356 0.996209135879357 DataSet_11_154
Klk7 Tbx1 knockout Ear Otic vesicles 0.666155 -0.58607 0.133760500670808 0.774817848943502 DataSet_11_155
Klk7 Wt1 siRNA Embryo_kidney LB-22 4.08951 2.03193 0.15278877485662 0.378448856604707 DataSet_11_179
Klk7 Yy1 knockout White_adipose_tissue Subcutaneous white adipose tissue 0.210546 -2.24779 0.252514989611374 0.732063709474324 DataSet_11_184
Klk7 Cpeb1 siRNA Neuron Neuro-2a 1.8022 0.849762 - - DataSet_11_189
Klk7 Hipk2 knockout Heart cardiac tissue 1.87662 0.908136 2.109512e-01 5.254010e-01 DataSet_11_238
Klk7 Dnmt1 knockout Embryo Embryonic fibroblasts 0.379747 -1.39689 4.589876e-01 6.263192e-01 DataSet_11_192
Klk7 Rag1 knockout Bone Mice fractured callus 0.60223 -0.731615 3.213392e-03 1.851993e-02 DataSet_11_230
Klk7 Dux siRNA Embryo ES cells 1.54167 0.624491 9.503722e-01 0.9963249564 DataSet_11_239
Klk7 Ncl siRNA Embryo ES cells 1.66667 0.736966 7.632655e-02 0.4265513172 DataSet_11_240
Klk7 Dnmt3a siRNA Embryo iPSC 0.540371 -0.887978 - - DataSet_11_241
Klk7 Ezh2 knockout Calvaria calvaria 0.25 -2 3.053235e-02 0.46193852 DataSet_11_247
Klk7 Kdm2a CRISPR Embryo ES cells 0.535714 -0.900464 0.0697488377 1.0000000 DataSet_11_251
Klk7 Eed knockout Brain Forebrain 1.56176 0.643177 1.284122e-01 6.737631e-01 DataSet_11_258
Klk7 Eed knockout Brain hindbrain 1.50475 0.58952 5.100211e-01 9.999914e-01 DataSet_11_259
Klk7 Eed knockout Brain midbrain 1.72155 0.78371 7.359990e-02 8.393901e-01 DataSet_11_260
Klk7 Eed knockout Spinal_cord spinal cord 2.36248 1.2403 1.819704e-01 9.999790e-01 DataSet_11_261
Klk7 Bcl3 knockout Bone Osteoblast 3 1.58496 4.172313e-01 7.519931e-01 DataSet_11_263
Klk7 Nsd2 knockout Bone_marrow Bone marrow immature B cells 0.589485 -0.762472 6.068446e-01 0.80504888 DataSet_11_267
Klk7 Nr4a1 knockout Mammary_gland PyVT mouse mammary tumor cells 0.422932 -1.2415 5.325427e-02 0.7273107 DataSet_11_268
Klk7 Mef2d CRISPR Heart Cardiac ventricle 1.78529 0.836159 2.157655e-01 0.4968110520 DataSet_11_270
Klk7 Kat6b shRNA Bone_marrow LT-HSCs 0.5 -1 7.287545e-01 0.8524915 DataSet_11_271
Klk7 Pcgf6 knockout Brain Brain 3.71089 1.89176 2.645203e-01 0.988876895 DataSet_11_280
Klk7 Zmat3 knockout Embryo Embryonic fibroblasts 2.05594 1.0398 7.349829e-01 0.8497686 DataSet_11_284
Klk7 Setd2 knockout Kidney primary renal tubular epithelial (RTE) cells 2.75 1.45943 - - DataSet_11_285
Klk7 Med19 knockout White_adipose_tissue Gonadal white adipose tissue 3.53346 1.82108 2.608672e-01 6.533619e-01 DataSet_11_289
Klk7 Tfap2a knockout Brain Brain 0.166667 -2.58496 0.2439570729 0.9599640 DataSet_11_295
Klk7 Ssrp1 CRISPR Embryo ES cells 0.517857 -0.949374 1.722256e-01 0.49552389 DataSet_11_296
Klk7 Arid2 knockout Muscle LSK 0.125 -3 4.535272e-03 1.861839e-01 DataSet_11_301
Klk7 Dnmt1 knockout Skin Keratinocytes 1.98456 0.988819 8.953286e-02 0.4002010687 DataSet_11_303
Klk7 Foxp3 CRISPR Spleens_and_lymphnodes CD4+ Th0 cells 0.491071 -1.026 - - DataSet_11_305
Klk7 Jmjd6 knockout Bone_marrow Lin-Sca1+Kit+ (LSK) haematopoietic stem and progenitor cells 0.6 -0.736966 - - DataSet_11_306
Klk7 Tbx20 knockdown Heart primary cardiac fibroblasts 0.272727 -1.87447 3.303297e-02 0.84403079 DataSet_11_309
Klk7 Actl6a knockout Nerve sciatic nerve 2.1875 1.12928 2.635091e-01 0.549299642 DataSet_11_314
Klk7 Kat7 knockout Thymic_lobes Thymic epithelial cells 0.3742 -1.41812 4.126764e-01 6.523023e-01 DataSet_11_319
Klk7 Kat7 knockout Thymic_lobes Thymic epithelial cells 0.295191 -1.76028 4.483196e-03 5.885915e-02 DataSet_11_320
Klk7 Prmt1 siRNA Adipose_tissue 3T3-L1 cells 9 3.16992 1.096429e-02 0.9832045 DataSet_11_325
Klk7 Snai1 knockdown Heart Heart 0.136179 -2.87642 1.353654e-02 0.08496182 DataSet_11_326
Klk7 Kdm5b siRNA Embryo ES cells 0.513623 -0.961218 0.4691028151 0.8933528 DataSet_11_331
Klk7 Dnmt3a siRNA Heart embryonic cardiomyocytes 2 1 7.206224e-01 0.93050249 DataSet_11_337
Klk7 Dnmt3b siRNA Heart embryonic cardiomyocytes 6 2.58496 1.928356e-02 0.42682687 DataSet_11_338
Klk7 Gtf2ird1 knockout Lip Lip 2.26887 1.18197 1.200675e-02 2.239290e-01 DataSet_11_339
Klk7 Dnmt1 siRNA Heart embryonic cardiomyocytes 2 1 4.443270e-01 0.532984351 DataSet_11_340
Klk7 Hnrnpk siRNA Embryo ES cells 2.43605 1.28455 5.655195e-02 0.101452917 DataSet_11_342
Klk7 Dnmt1 knockout Kidney kidney Cap Mesenchyme 2.53876 1.34413 1.022637e-01 3.350593e-01 DataSet_11_344
Klk7 Gata4 CRISPR Heart primary cardiac fibroblasts 0.272727 -1.87447 3.303297e-02 0.84403079 DataSet_11_347
Klk7 Tbx20 CRISPR Heart primary cardiac fibroblasts 0.363636 -1.45943 2.008300e-02 1.00000000 DataSet_11_348
Regulation Region
 
T(co)Fs that significantly regulate Prmt1 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of Klk7
T(co)F Expression in Mouse Cell (Fantom5) T(co)F Expression in Mouse Tissue (Fantom5)