Gene Overview
| Target Gene: | Lypd6 |
| NCBI Official Symbol: | Lypd6 |
| Entrez ID: | 320343 |
| Ensembl ID: | ENSMUSG00000050447 |
| Gene Full Name: | LY6/PLAUR domain containing 6 |
| Strand: | + |
| Gene Locus: | 2|2 C1.1 |
| External Links: |
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Lypd6 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Lypd6
T(co)Fs
that Repress Lypd6
The Intensity of the Gene Regulated by T(co)Fs:
Lypd6-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Lypd6 | Cbx2 | knockout | Gonads | Embryonic gonads | 0.409834 | -1.28689 | 1.6432260463758e-09 | 1.93648587658412e-07 | DataSet_11_018 |
| Lypd6 | Elf5 | knockout | Mammary_gland | Mammary gland | 0.591512 | -0.757521 | 0.111308935026141 | 0.395230841960628 | DataSet_11_035 |
| Lypd6 | Hsf4 | knockout | Eye | Lens | 0.646659 | -0.628922 | 0.530746510084049 | 0.987999303842427 | DataSet_11_058 |
| Lypd6 | Lhx8 | knockout | Ovary | Ovary | 0.611639 | -0.709248 | 0.00444887706188642 | 0.033590884288528 | DataSet_11_070 |
| Lypd6 | Lmx1b | knockout | Kidney | Kidney | 1.51735 | 0.601554 | 0.0569055365157021 | 0.425484257833423 | DataSet_11_072 |
| Lypd6 | Mbd1 | siRNA | Adipose_tissue | 3T3-L1 cells | 0.526627 | -0.925146 | - | - | DataSet_11_074 |
| Lypd6 | Neurod1 | knockout | Eye | Retina | 1.74543 | 0.80358 | 2.13716633360893e-05 | 0.00121129124047419 | DataSet_11_088 |
| Lypd6 | Neurod1 | knockout | Eye | Pineal gland | 0.622473 | -0.683916 | 0.0705680442759796 | 0.9983937273602 | DataSet_11_089 |
| Lypd6 | Npas4 | RNAi | Brain | Hippocampal Neurons | 2.64831 | 1.40507 | 7.48861752737772e-10 | 9.69482759013949e-08 | DataSet_11_093 |
| Lypd6 | Nrf1 | knockdown | Liver | Liver | 2.80219 | 1.48656 | 0.0049847939336401 | 0.0356632429261029 | DataSet_11_096 |
| Lypd6 | Otx2 | knockout | Eye | Retina | 0.552779 | -0.855224 | 0.482667713818118 | 0.999923528647439 | DataSet_11_097 |
| Lypd6 | Plagl2 | knockout | Intestine | Small intestine | 0.417704 | -1.25945 | 0.00302890136421755 | 0.0528312745100991 | DataSet_11_104 |
| Lypd6 | Prdm2 | shRNA | Muscle | C2C12 | 0.51088 | -0.968945 | 0.142408100789878 | 0.884340202464774 | DataSet_11_108 |
| Lypd6 | Prox1 | knockout | Liver | Liver | 9.20399 | 3.20226 | - | - | DataSet_11_109 |
| Lypd6 | Sall1 | knockout | Kidney | Kidney | 1.53925 | 0.622228 | 0.120261786126792 | 0.921181351385577 | DataSet_11_122 |
| Lypd6 | Smad4 | siRNA | Brain | bEnd3 | 0.248249 | -2.01014 | - | - | DataSet_11_127 |
| Lypd6 | Snai1 | knockout | Embryo | Embryoid body | 0.266337 | -1.90868 | - | - | DataSet_11_129 |
| Lypd6 | Stat6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 1.67518 | 0.744315 | 0.0441542260782799 | 0.135734815931466 | DataSet_11_153 |
| Lypd6 | Cpeb1 | siRNA | Neuron | Neuro-2a | 0.132914 | -2.91143 | - | - | DataSet_11_189 |
| Lypd6 | Dnmt3a | knockout | Skeletal_muscle | Satellite cells | 0.660256 | -0.598902 | 2.588555e-01 | 1.0000000 | DataSet_11_208 |
| Lypd6 | Ncl | siRNA | Embryo | ES cells | 0.592179 | -0.755895 | 7.168942e-02 | 0.4187381622 | DataSet_11_240 |
| Lypd6 | Dnmt3a | siRNA | Embryo | iPSC | 0.400277 | -1.32093 | - | - | DataSet_11_241 |
| Lypd6 | Lin28a | knockout | Heart | Heart | 0.507669 | -0.97804 | 0.3973710900 | 0.8777652 | DataSet_11_243 |
| Lypd6 | Kmt2d | knockout | Skin | iBiP melanoma mouse model tumor cell | 0.66 | -0.599462 | 3.086827e-01 | 4.695686e-01 | DataSet_11_250 |
| Lypd6 | Zbp1 | siRNA | Bone_marrow | bone marrow-derived mesenchymal stem_progenitor cells | 3.71167 | 1.89207 | 3.755710e-02 | 0.126211487 | DataSet_11_252 |
| Lypd6 | Fubp1 | shRNA | Bone_marrow | BM cells | 2 | 1 | 5.223506e-01 | 0.894794069 | DataSet_11_262 |
| Lypd6 | Ctnnb1 | knockout | Embryo | MGE cells | 2.06705 | 1.04758 | 6.904900e-01 | 0.827880553 | DataSet_11_266 |
| Lypd6 | Dux | knockout | Embryo | Embryo | 2.32948 | 1.22001 | 8.596256e-04 | 6.095716e-03 | DataSet_11_269 |
| Lypd6 | Kat6b | shRNA | Bone_marrow | LT-HSCs | 1.63636 | 0.710493 | 1.985415e-01 | 0.6076680 | DataSet_11_271 |
| Lypd6 | Dux | knockout | Embryo | Embryo | 2.32948 | 1.22001 | 8.596225e-04 | 6.095099e-03 | DataSet_11_273 |
| Lypd6 | Myod1 | CRISPR | Skeletal_muscle | myoblast | 0.00606375 | -7.36557 | 4.002139e-05 | 3.865837e-04 | DataSet_11_275 |
| Lypd6 | Gsk3b | CRISPR | Neuron | mPFC D2 neurons | 1.60622 | 0.683665 | 2.584187e-01 | 0.85266614 | DataSet_11_277 |
| Lypd6 | Ssrp1 | CRISPR | Embryo | ES cells | 2.0411 | 1.02934 | 9.740596e-02 | 0.7762809 | DataSet_11_278 |
| Lypd6 | Usp7 | knockout | Embryo | ES cells | 2.88461 | 1.52838 | 7.042463e-03 | 0.2150674 | DataSet_11_279 |
| Lypd6 | Setd2 | knockout | Kidney | primary renal tubular epithelial (RTE) cells | 0.520938 | -0.940816 | - | - | DataSet_11_285 |
| Lypd6 | Usp7 | siRNA | Embryo | ES cells | 2.75439 | 1.46173 | 4.763276e-02 | 0.6667924 | DataSet_11_287 |
| Lypd6 | Kmt2d | CRISPR | Liver | MA1L | 3.44576 | 1.78482 | 5.501735e-02 | 2.060946e-01 | DataSet_11_290 |
| Lypd6 | Kmt2d | CRISPR | Liver | MA1L | 3.51985 | 1.81551 | 5.235599e-02 | 1.924095e-01 | DataSet_11_291 |
| Lypd6 | Ssrp1 | CRISPR | Embryo | ES cells | 3.26087 | 1.70526 | 5.267447e-02 | 0.28440363 | DataSet_11_296 |
| Lypd6 | Phf8 | knockout | prostate | Prostate | 2.44118 | 1.28758 | 0.0267367445 | 0.2031882 | DataSet_11_298 |
| Lypd6 | Arid2 | knockout | Muscle | LSK | 0.0588235 | -4.08746 | 9.988105e-05 | 1.312187e-02 | DataSet_11_301 |
| Lypd6 | Jmjd6 | knockout | Bone_marrow | Lin-Sca1+Kit+ (LSK) haematopoietic stem and progenitor cells | 0.5 | -1 | - | - | DataSet_11_306 |
| Lypd6 | Cited2 | knockout | Haematopoietic_and_lymphoid_tissue | Hematopoietic stem cell (HSC) | 1.86207 | 0.896906 | - | - | DataSet_11_308 |
| Lypd6 | Actl6a | knockout | Nerve | sciatic nerve | 1.59618 | 0.674621 | 4.357604e-02 | 0.287741101 | DataSet_11_314 |
| Lypd6 | Ahr | knockout | Liver | Liver | 0.630435 | -0.665581 | 4.994764e-01 | 0.7860327214 | DataSet_11_315 |
| Lypd6 | Setdb1 | shRNA | Neuron | NE-4C | 2.70405 | 1.43512 | - | - | DataSet_11_323 |
| Lypd6 | Snai1 | knockdown | Heart | Heart | 0.498339 | -1.0048 | 2.261347e-02 | 0.11551286 | DataSet_11_326 |
| Lypd6 | Tet1 | siRNA | Embryo | Embryonic fibroblasts | 2 | 1 | 5.738176e-01 | 0.9609895 | DataSet_11_327 |
| Lypd6 | Kdm5b | siRNA | Embryo | ES cells | 0.145022 | -2.78565 | 0.4403383514 | 0.8933528 | DataSet_11_331 |
| Lypd6 | Ezh2 | shRNA | Brain | SVZ derived neural stem cells | 0.312465 | -1.67824 | 3.174046e-02 | 1.898309e-01 | DataSet_11_332 |
| Lypd6 | Ezh2 | knockout | Eye | Retina | 3.07354 | 1.6199 | 0.2066413141 | 1.0000000 | DataSet_11_334 |
| Lypd6 | Atrx | knockout | Embryo | ES cells | 0.214286 | -2.22239 | - | - | DataSet_11_335 |
| Lypd6 | Dnmt3a | knockout | Peritoneum | peritoneal macrophages | 2.05693 | 1.04049 | - | - | DataSet_11_336 |
| Lypd6 | Gtf2ird1 | knockout | Lip | Lip | 0.35894 | -1.47818 | 2.880617e-03 | 1.087900e-01 | DataSet_11_339 |
| Lypd6 | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 0.618321 | -0.693573 | 1.681709e-01 | 0.286350857 | DataSet_11_340 |
| Lypd6 | Ezh2 | knockout | Small_intestinal_crypts | small intestinal crypts | 4.86667 | 2.28293 | 0.0416249899 | 0.1712697 | DataSet_11_341 |
| Lypd6 | Hnrnpk | siRNA | Embryo | ES cells | 0.591867 | -0.756656 | 8.989595e-03 | 0.025512415 | DataSet_11_342 |
| Lypd6 | Dnmt1 | knockout | Kidney | kidney Cap Mesenchyme | 1.97121 | 0.979082 | 2.454977e-02 | 1.677807e-01 | DataSet_11_344 |
Regulation Region
Expression Atlas of Lypd6