Gene Overview
| Target Gene: | Pvalb |
| NCBI Official Symbol: | Pvalb |
| Entrez ID: | 19293 |
| Ensembl ID: | ENSMUSG00000005716 |
| Gene Full Name: | parvalbumin |
| Strand: | - |
| Gene Locus: | 15 E1|15 36.93 cM |
| External Links: |
|
Pvalb Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Pvalb
T(co)Fs
that Repress Pvalb
The Intensity of the Gene Regulated by T(co)Fs:
Pvalb-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Pvalb | Arid1a | knockout | Ovary | Ovary | 1.56743 | 0.648403 | 0.00843836604569013 | 0.94648870498129 | DataSet_11_005 |
| Pvalb | Bcl6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 1.67647 | 0.745427 | 0.533699872253033 | 0.794317390785421 | DataSet_11_014 |
| Pvalb | Bhlha9 | knockout | Limb | Whole limb bud | 0.311191 | -1.68413 | - | - | DataSet_11_016 |
| Pvalb | Cebpb | knockout | Mammary_gland | Mammary epithlial cells (MECs) | 3.3058 | 1.725 | 0.0243796438140524 | 0.999788745984441 | DataSet_11_020 |
| Pvalb | Elf5 | knockout | Mammary_gland | Mammary gland | 2.44829 | 1.29177 | 0.0532253548008641 | 0.318783449010893 | DataSet_11_035 |
| Pvalb | Esrrb | shRNA | Embryo | ES cells | 1.76674 | 0.82109 | - | - | DataSet_11_039 |
| Pvalb | Foxa2 | knockout | Lung | Whole lung | 0.454859 | -1.13651 | 0.298773300825178 | 0.70187530098709 | DataSet_11_041 |
| Pvalb | Gata2 | knockout | Kidney | renal collecting duct cells | 0.379297 | -1.3986 | - | - | DataSet_11_047 |
| Pvalb | Gfi1 | knockout | Cord_Blood | T-cells | 1.5934 | 0.672105 | 0.152400769418512 | 0.559908148618527 | DataSet_11_053 |
| Pvalb | Hoxc13 | knockout | Skin | Skin | 0.598048 | -0.741667 | 0.182486172405013 | 0.543913295038203 | DataSet_11_057 |
| Pvalb | Jarid2 | knockout | Pancreas | Embryonic pancreas | 1.85185 | 0.888969 | 0.168531541414468 | 0.805007869400291 | DataSet_11_064 |
| Pvalb | Lhx8 | knockout | Ovary | Ovary | 0.455326 | -1.13503 | 0.188212811925965 | 0.340075087739039 | DataSet_11_070 |
| Pvalb | Mafg | knockout | Embryo | Whole embryo | 1.71622 | 0.779231 | 0.130376788336325 | 1 | DataSet_11_073 |
| Pvalb | Mef2a | shRNA | Muscle | C2C12 | 1.76425 | 0.819056 | 6.83549171493831e-05 | 0.000943495707993287 | DataSet_11_077 |
| Pvalb | Nr2f2 | knockout | Ovary | E16.5 Ovary | 4.271 | 2.09457 | 0.00100889635578097 | 0.133283562517536 | DataSet_11_095 |
| Pvalb | Pparg | siRNA | Adipose_tissue | Preadipocytes | 0.204486 | -2.28993 | 0.621409528283132 | 0.999962577291099 | DataSet_11_105 |
| Pvalb | Prox1 | knockout | Liver | Liver | 0.146199 | -2.77399 | - | - | DataSet_11_109 |
| Pvalb | Rest | knockout | Brain | Brain | 0.64678 | -0.628652 | 0.0918571737834995 | 1 | DataSet_11_113 |
| Pvalb | Runx1 | knockout | Lymph | ProB cells | 0.594431 | -0.750419 | 0.374691847921983 | 0.715627673508652 | DataSet_11_116 |
| Pvalb | Runx1 | knockout | Mammary_gland | Luminal epithelial cells | 1.54052 | 0.623418 | 0.298232694143638 | 0.999784944667092 | DataSet_11_117 |
| Pvalb | Runx2 | knockout | Humeri | Embryonic humeri | 0.571245 | -0.807819 | 0.0275010670459701 | 0.334547558582564 | DataSet_11_120 |
| Pvalb | Smad4 | knockout | Aorta | Aortic arteries | 4.15173 | 2.05371 | 0.262666861645475 | 0.679383137222696 | DataSet_11_128 |
| Pvalb | Sox11 | knockout | Eye | Retina | 0.224806 | -2.15325 | - | - | DataSet_11_137 |
| Pvalb | Sox9 | knockout | Lung | Trachea | 6.73484 | 2.75164 | 0.000284366024038329 | 0.028094183899697 | DataSet_11_144 |
| Pvalb | Spdef | knockout | Colon | Colon | 0.615964 | -0.699082 | 0.46633647179445 | 0.997507742354799 | DataSet_11_146 |
| Pvalb | Spdef | knockout | Stomach | Stomach | 2.19414 | 1.13366 | 0.21237621544027 | 0.895115884805627 | DataSet_11_147 |
| Pvalb | Stat4 | knockout | Lymph | Lamina propria lymphocytes | 0.422312 | -1.24362 | 0.240147834416716 | 0.924261066168849 | DataSet_11_152 |
| Pvalb | Tbx1 | knockout | Ear | Otic vesicles | 0.485072 | -1.04373 | 0.331670105221458 | 0.996209135879357 | DataSet_11_154 |
| Pvalb | Tet2 | knockout | Kidney | Kidney | 0.293647 | -1.76784 | 0.265111140748657 | 1 | DataSet_11_159 |
| Pvalb | Thap1 | knockout | Brain | Cerebellum | 6.30522 | 2.65655 | 3.39000155509487e-08 | 4.38763058416565e-06 | DataSet_11_164 |
| Pvalb | Thap1 | knockout | Brain | Cortex | 6.62722 | 2.7284 | 2.87476500377853e-08 | 3.51964472084236e-06 | DataSet_11_165 |
| Pvalb | Vdr | knockout | Bone_marrow | Bone marrow-derived macrophages | 3.83823 | 1.94044 | 0.00770892135948315 | 0.947833698850414 | DataSet_11_174 |
| Pvalb | Wt1 | siRNA | Embryo_kidney | LB-22 | 0.607981 | -0.717903 | 0.0413237552906525 | 0.175742466369371 | DataSet_11_179 |
| Pvalb | Yy1 | knockout | White_adipose_tissue | Subcutaneous white adipose tissue | 2.12955 | 1.09055 | 0.677279724133318 | 0.913351469584715 | DataSet_11_184 |
| Pvalb | Pogz | knockdown | Liver | fetal liver | 0.288178 | -1.79497 | 1.420080e-02 | 0.3028267 | DataSet_11_188 |
| Pvalb | Siah2 | knockout | Heart | Primary isolated cells | 1.53266 | 0.616036 | 1.158550e-02 | 0.99981862 | DataSet_11_235 |
| Pvalb | Mapk9 | knockout | Hip | Mouse Hip Cartilage | 0.136116 | -2.87709 | 1.453881e-05 | 1.680347e-04 | DataSet_11_236 |
| Pvalb | Hipk2 | knockout | Heart | cardiac tissue | 3.22046 | 1.68727 | 9.931933e-02 | 3.901741e-01 | DataSet_11_238 |
| Pvalb | Kdm5b | knockout | Heart | left ventricles | 0.478665 | -1.06291 | 0.2508751910 | 0.9999827 | DataSet_11_210 |
| Pvalb | Dnmt1 | knockout | Embryo | Embryonic fibroblasts | 1.58424 | 0.66379 | 1.697032e-01 | 3.360582e-01 | DataSet_11_192 |
| Pvalb | Ezh1 | knockout | Muscle | LSK | 2.25012 | 1.17 | 0.0390477737 | 0.08264437 | DataSet_11_233 |
| Pvalb | Prdm11 | knockout | Lung | Lung | 1.68631 | 0.753869 | 3.146806e-01 | 0.499724903 | DataSet_11_198 |
| Pvalb | Ezh2 | knockdown | Brain | Brain | 0.0976254 | -3.3566 | 1.343109e-06 | 0.0015541375 | DataSet_11_221 |
| Pvalb | Dnmt3b | knockout | Heart | Cardiac ventricle | 0.275825 | -1.85817 | 1.055799e-01 | 9.999725e-01 | DataSet_11_205 |
| Pvalb | Bptf | shRNA | Mammary_gland | 4T1 cells | 0.221698 | -2.17333 | 1.252905e-01 | 0.564380645 | DataSet_11_223 |
| Pvalb | Dnmt3a | knockout | Skeletal_muscle | Satellite cells | 1.55982 | 0.64138 | 2.653266e-01 | 1.0000000 | DataSet_11_208 |
| Pvalb | Kat6a | knockout | Embryo | Embryonic fibroblasts | 0.133333 | -2.90689 | 6.197826e-03 | 0.0749685798 | DataSet_11_245 |
| Pvalb | Kmt2d | knockout | Skin | iBiP melanoma mouse model tumor cell | 0.166667 | -2.58496 | 4.721249e-01 | 6.074683e-01 | DataSet_11_250 |
| Pvalb | Mecp2 | knockout | Adipose_tissue | brown adipose tissue | 1.73295 | 0.79323 | 8.917523e-01 | 0.962184569 | DataSet_11_253 |
| Pvalb | Mecp2 | knockout | Adipose_tissue | inguinal adipose tissue | 6.17125 | 2.62556 | 8.965925e-02 | 0.3109492 | DataSet_11_254 |
| Pvalb | Eed | knockout | Brain | Forebrain | 1.99804 | 0.998584 | 5.136604e-02 | 5.249917e-01 | DataSet_11_258 |
| Pvalb | Eed | knockout | Brain | midbrain | 0.26693 | -1.90547 | 2.147888e-01 | 9.620062e-01 | DataSet_11_260 |
| Pvalb | Eed | knockout | Spinal_cord | spinal cord | 1.71803 | 0.780756 | 5.073871e-01 | 9.999790e-01 | DataSet_11_261 |
| Pvalb | Bcl3 | knockout | Bone | Osteoblast | 2.7551 | 1.46211 | 2.762979e-02 | 6.038992e-01 | DataSet_11_263 |
| Pvalb | Ctnnb1 | knockout | Embryo | MGE cells | 1.80525 | 0.852198 | 2.354051e-01 | 0.540920333 | DataSet_11_266 |
| Pvalb | Dux | knockout | Embryo | Embryo | 5.79644 | 2.53517 | 2.927592e-01 | 4.775167e-01 | DataSet_11_269 |
| Pvalb | Mef2d | CRISPR | Heart | Cardiac ventricle | 0.119042 | -3.07046 | 7.408455e-02 | 0.2848206816 | DataSet_11_270 |
| Pvalb | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 0.0575149 | -4.11992 | 3.070627e-01 | 0.81420760 | DataSet_11_272 |
| Pvalb | Dux | knockout | Embryo | Embryo | 5.79644 | 2.53517 | 2.927605e-01 | 4.775705e-01 | DataSet_11_273 |
| Pvalb | Lin28b | knockout | Bone_marrow | Bone marrow immature B cells | 2 | 1 | 7.802090e-01 | 0.9878520 | DataSet_11_274 |
| Pvalb | Dnmt1 | knockout | Cortex | mature Pvergic cortical interneurons | 0.2 | -2.32193 | 8.817282e-02 | 0.6936949 | DataSet_11_283 |
| Pvalb | Usp7 | siRNA | Embryo | ES cells | 0.5 | -1 | 6.264997e-01 | 0.7767490 | DataSet_11_287 |
| Pvalb | Med19 | knockout | White_adipose_tissue | Gonadal white adipose tissue | 3.13067 | 1.64647 | 4.161232e-01 | 7.460275e-01 | DataSet_11_289 |
| Pvalb | Ssrp1 | CRISPR | Embryo | ES cells | 3 | 1.58496 | 6.168637e-01 | 0.77319976 | DataSet_11_296 |
| Pvalb | Sirt3 | knockout | Pancreatic_islets | pancreatic beta cell | 0.263158 | -1.926 | 5.903379e-01 | 8.432223e-01 | DataSet_11_297 |
| Pvalb | Phf8 | knockout | prostate | Prostate | 0.00384615 | -8.02237 | 0.0065547950 | 0.1692446 | DataSet_11_298 |
| Pvalb | Brpf1 | shRNA | Nerve | Neural progenitor cells | 2.65009 | 1.40604 | 6.652779e-02 | 0.9999903 | DataSet_11_299 |
| Pvalb | Dnmt1 | knockout | Skin | Keratinocytes | 0.625851 | -0.67611 | 8.061719e-01 | 0.9273113283 | DataSet_11_303 |
| Pvalb | Cited2 | knockout | Haematopoietic_and_lymphoid_tissue | Hematopoietic stem cell (HSC) | 3 | 1.58496 | - | - | DataSet_11_308 |
| Pvalb | Actl6a | knockout | Nerve | sciatic nerve | 16.816 | 4.07176 | 1.081290e-01 | 0.392117851 | DataSet_11_314 |
| Pvalb | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.130986 | -2.93252 | 4.958905e-03 | 2.181289e-01 | DataSet_11_319 |
| Pvalb | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.293651 | -1.76783 | 1.268586e-03 | 3.332409e-02 | DataSet_11_320 |
| Pvalb | Bud31 | knockout | Testis | Spermatogonial stem cells | 0.0740741 | -3.75489 | 1.994390e-01 | 0.8600602 | DataSet_11_321 |
| Pvalb | Snai1 | knockdown | Heart | Heart | 0.583439 | -0.777347 | 1.297972e-03 | 0.02750867 | DataSet_11_326 |
| Pvalb | Ezh2 | shRNA | Brain | SVZ derived neural stem cells | 13 | 3.70044 | 3.006979e-02 | 1.835939e-01 | DataSet_11_332 |
| Pvalb | Gtf2ird1 | knockout | Lip | Lip | 0.424998 | -1.23447 | 7.641950e-03 | 1.774123e-01 | DataSet_11_339 |
| Pvalb | Dux | shRNA | Embryo | ES cells | 0.5 | -1 | 4.507023e-01 | 8.152042e-01 | DataSet_11_345 |
Regulation Region
Expression Atlas of Pvalb