Gene Overview
Target Gene: ZBTB41
NCBI Official Symbol: ZBTB41
Entrez ID: 360023
Ensembl ID: ENSG00000177888
Gene Full Name: zinc finger and BTB domain containing 41
Strand: -
Gene Locus: 1q31.3
External Links:

ZBTB41 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate ZBTB41   
T(co)Fs that Repress ZBTB41
The Intensity of the Gene Regulated by T(co)Fs:
ZBTB41-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
ZBTB41 HNF1B shRNA Ovary RMG2 1.54106 0.62393 0.00843 0.02268 DataSet_01_103
ZBTB41 FOXA1 shRNA Prostate 22RV1 0.66646 -0.58542 - - DataSet_01_105
ZBTB41 FOXO1 shRNA Bone EWS-FLI1 0.62815 -0.67081 0.00318 0.10366 DataSet_01_106
ZBTB41 ZIC2 siRNA Pancreas PANC1 7.01783 2.81102 - - DataSet_01_121
ZBTB41 ZNF85 siRNA Gastrointestinal_tissue GIST-T1 0.64125 -0.64104 0.00083 0.00937 DataSet_01_126
ZBTB41 NFYA shRNA Cervix HeLaS3 0.53648 -0.8984 0.01063 0.08119 DataSet_01_131
ZBTB41 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.73272 0.79304 0.09622 0.86138 DataSet_01_137
ZBTB41 SF1 siRNA Adrenal_gland H295R/TR 0.6321 -0.66178 0.00703 0.03482 DataSet_01_146
ZBTB41 LIN28B siRNA Embryo_kidney HEK293 0.54662 -0.87139 0.00301 0.03114 DataSet_01_153
ZBTB41 STAT3 siRNA Peripheral_blood CD4+ T cells 0.5975 -0.743 0.14253 0.99183 DataSet_01_168
ZBTB41 TP53 siRNA Lung SAECs 0.51269 -0.96385 0.02219 0.30892 DataSet_01_175
ZBTB41 TP63 siRNA Head_and_neck SCC-1 0.53315 -0.90738 - - DataSet_01_199
ZBTB41 XBP1 shRNA Mammary_gland T47D 1.64674 0.71961 0.00012 0.00143 DataSet_01_203
ZBTB41 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 0.62856 -0.66987 - - DataSet_01_209
ZBTB41 SNAI2 shRNA Skin Primary human keratinocytes 0.6516 -0.61795 0.00653 0.03703 DataSet_01_225
ZBTB41 STAT5 shRNA Haematopoietic_and_lymphoid_tissue K562 2.19076 1.13143 1.29736e-05 0.00053 DataSet_01_239
ZBTB41 EGR2 siRNA Muscle A673 1.52633 0.61007 0.29371 0.79428 DataSet_01_242
ZBTB41 YBX1 shRNA Mammary_gland MDA 2.31233 1.20934 1.25465e-05 0.00052 DataSet_01_257
ZBTB41 STAT5 shRNA Prostate CWR22Pc 0.5233 -0.93429 0.00054 0.01194 DataSet_01_279
ZBTB41 NFYA shRNA Colon HCT1163 0.56001 -0.83648 0.00173 0.02905 DataSet_01_287
ZBTB41 NFYA shRNA Lung H322 0.65194 -0.6172 0.00024 0.003 DataSet_01_288
ZBTB41 TFAP4 siRNA Brain BE(2)-C 0.6086 -0.71644 0.86403 0.86586 DataSet_01_295
ZBTB41 PTEN shRNA Skin A431 1.91269 0.9356 0.01122 0.09977 DataSet_01_301
ZBTB41 ETV5 siRNA Soft_tissue hADSC 0.59779 -0.7423 0.00254 0.03396 DataSet_01_304
ZBTB41 BRD4 siRNA Ovary Ovcar8 1.71606 0.7791 0.00012 0.00218 DataSet_01_311
ZBTB41 OVOL2 siRNA Corneal_epithelial Corneal epithelial cells 1.68154 0.74978 0.03915 0.30522 DataSet_01_313
ZBTB41 MYC siRNA Colon HCT116 1.73572 0.79554 2.87519e-06 2.05704e-05 DataSet_01_324
ZBTB41 STAT3 siRNA Liver LX-2 0.56619 -0.82063 1.26869e-05 0.00021 DataSet_01_334
ZBTB41 HIF1A siRNA Oral_cavity OEC-M1 0.61176 -0.70897 0.10404 0.85151 DataSet_01_348
ZBTB41 SAFB2 shRNA Liver HepG2 0.6352 -0.65471 0.05279 0.11014 DataSet_02_102
ZBTB41 U2AF2 shRNA Liver HepG2 1.60052 0.67854 0.31864 0.46759 DataSet_02_105
ZBTB41 RBM39 shRNA Liver HepG2 0.65412 -0.61238 0.02957 0.22203 DataSet_02_111
ZBTB41 XRCC5 shRNA Liver HepG2 1.60836 0.68559 0.01499 0.1507 DataSet_02_114
ZBTB41 PCBP1 shRNA Liver HepG2 0.62908 -0.66868 0.00784 0.02893 DataSet_02_115
ZBTB41 RBM25 shRNA Liver HepG2 1.56973 0.65052 0.005 0.03027 DataSet_02_119
ZBTB41 PTBP1 shRNA Liver HepG2 1.78635 0.83701 0.00167 0.00843 DataSet_02_120
ZBTB41 SRSF3 shRNA Liver HepG2 1.51923 0.60334 0.04367 0.14765 DataSet_02_127
ZBTB41 PRPF4 shRNA Liver HepG2 0.65854 -0.60266 0.03777 0.10783 DataSet_02_128
ZBTB41 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.65456 0.72645 0.01497 0.19832 DataSet_02_144
ZBTB41 FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.48547 -1.04255 0.00162 0.08322 DataSet_02_147
ZBTB41 U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.52061 0.60465 0.01003 0.13876 DataSet_02_165
ZBTB41 EWSR1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.60178 -0.7327 0.00562 0.22555 DataSet_02_167
ZBTB41 ATF3 siRNA Haematopoietic_and_lymphoid_tissue K562 0.52885 -0.91908 0.10642 1 DataSet_02_180
ZBTB41 STAT5A siRNA Haematopoietic_and_lymphoid_tissue K562 0.55515 -0.84906 0.30083 1 DataSet_02_182
ZBTB41 RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 1.58942 0.6685 0.77758 1 DataSet_02_190
ZBTB41 ARID1A siRNA Oral_cavity SAS cells 0.604817 -0.72543 0.436661090994682 0.824061028827408 DataSet_03_013
ZBTB41 ATR siRNA Mammary_gland MCF7 0.644231 -0.63435 0.0884768073889518 0.999819450785634 DataSet_03_020
ZBTB41 CREBBP siRNA Mammary_gland MCF7 1.67177 0.741381 0.054605639580209 0.963067261754673 DataSet_03_055
ZBTB41 CTNNB1 siRNA Mammary_gland MCF7 1.5976 0.675911 0.0733282132691287 0.999436862066063 DataSet_03_058
ZBTB41 ERBB2 siRNA Mammary_gland MCF7 1.69406 0.760487 0.0501257587953127 0.998282799776643 DataSet_03_066
ZBTB41 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 2.62239 1.39088 - - DataSet_03_096
ZBTB41 HDAC3 siRNA Mammary_gland MCF7 0.64456 -0.633614 0.0887714829657709 0.99997791025972 DataSet_03_114
ZBTB41 HSF1 siRNA Liver HepG2 1.76543 0.82002 0.0878447432555829 1 DataSet_03_129
ZBTB41 JARID1A siRNA Autonomic_ganglia SKNBE2 1.57448 0.654876 0.00849634014267327 0.249153423448027 DataSet_03_135
ZBTB41 MAPK1 siRNA Mammary_gland MCF7 0.655202 -0.609989 0.290684621225422 0.999829384224364 DataSet_03_156
ZBTB41 MAX siRNA Mammary_gland MCF7 0.612941 -0.70618 0.0639699437590986 0.999907009675999 DataSet_03_158
ZBTB41 MCM2 siRNA Mammary_gland MCF7 0.515993 -0.954578 0.0214207661327242 0.999925560383539 DataSet_03_161
ZBTB41 MITF siRNA Skin SK-MEL-5 0.659822 -0.599852 0.0107609381334871 0.0225236914570229 DataSet_03_168
ZBTB41 MYC siRNA Colon HT29 1.57062 0.65133 - - DataSet_03_177
ZBTB41 MYCN siRNA Brain BE(2)C cells 2.35283 1.2344 - - DataSet_03_188
ZBTB41 NCOR2 siRNA Mammary_gland MCF7 0.551003 -0.859867 0.032270477837189 0.999834929103349 DataSet_03_193
ZBTB41 NFKB1 siRNA Central_nervous_system U251 0.646479 -0.629325 0.109175434451071 0.224309680782486 DataSet_03_197
ZBTB41 NR4A3 siRNA Pancreas 1.1B4 1.58386 0.663445 3.96507657318988e-05 0.000404074041972414 DataSet_03_203
ZBTB41 PAX3 siRNA Mammary_gland MCF7 0.610957 -0.710857 0.196112742242655 0.919978041032696 DataSet_03_206
ZBTB41 RELB siRNA Pancreas MIA PaCa-2 0.253819 -1.97812 0.000581621897862001 0.0237822132867889 DataSet_03_225
ZBTB41 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 0.276423 -1.85505 - - DataSet_03_246
ZBTB41 SP1 siRNA Cervix HeLa 1.5332 0.616542 6.0207028615033e-05 0.00133553185907389 DataSet_03_249
ZBTB41 TET2 siRNA Prostate DU145 0.562101 -0.8311 - - DataSet_03_271
ZBTB41 TET3 siRNA Embryo NCCIT 1.60688 0.68426 0.000145481120585631 0.005573918064143 DataSet_03_273
ZBTB41 TP53 siRNA Foreskin Neonatal foreskin keratinocytes 1.50305 0.587896 0.0584806179856749 0.999791649573014 DataSet_03_278
ZBTB41 TP63 siRNA Skin Primary neonatal keratinocytes 0.539911 -0.889207 0.00974273636689476 0.0472623109375237 DataSet_03_281
ZBTB41 TP63 siRNA Foreskin Neonatal foreskin keratinocytes 1.54521 0.627805 0.0309360917194559 0.729684006943091 DataSet_03_282
ZBTB41 TWIST1 siRNA Bone_marrow MSCs 0.581006 -0.783376 - - DataSet_03_283
ZBTB41 WT1 siRNA Mammary_gland MCF7 0.591434 -0.757711 0.0507524715802383 0.999957852801679 DataSet_03_285
ZBTB41 CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.58834 0.667519 0.00148061125614967 0.0205510046102564 DataSet_04_004
ZBTB41 MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.479356 -1.06083 0.00302721241430006 0.0162579266893535 DataSet_04_012
ZBTB41 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 7.55017 2.91651 0.0332284313756081 0.104914770342872 DataSet_04_014
ZBTB41 NUP35 shRNA Haematopoietic_and_lymphoid_tissue K562 0.460222 -1.1196 0.00900895508093647 0.0306864462326118 DataSet_04_015
ZBTB41 ACTN4 CRISPR Liver HepG2 1.99087 0.993397 0.0198576016413949 0.0786659296327143 DataSet_04_042
ZBTB41 CNOT7 shRNA Liver HepG2 1.62439 0.699898 0.0162915398558679 0.0412938484276805 DataSet_04_051
ZBTB41 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.81271 0.858147 0.00301245821073175 0.0210595555762786 DataSet_02_35
ZBTB41 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.75585 0.812172 0.252194835710293 0.523191892773458 DataSet_02_32
ZBTB41 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.91639 0.93839 0.00450430340338261 0.0206054090155911 DataSet_02_33
ZBTB41 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.5786 0.658641 0.00195859447174926 0.0332299583195934 DataSet_02_53
ZBTB41 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 0.487412 -1.03679 0.00142741570906045 0.00851649306963636 DataSet_04_059
ZBTB41 EZH2 knockdown Uterus Ishikawa (ISK) cell 0.473576 -1.07833 - - DataSet_03_324
ZBTB41 SMARCA4 siRNA Colon HCT116 2.75313 1.46107 7.870941e-03 2.821730e-01 DataSet_03_301
ZBTB41 HDAC4 siRNA Liver human hepatocytes 0.636331 -0.65215 3.368477e-05 2.816125e-03 DataSet_03_345
ZBTB41 ACTR5 siRNA Muscle RD 3.24021 1.69609 - - DataSet_03_343
ZBTB41 INO80 siRNA Muscle RD 2.65253 1.40737 - - DataSet_03_344
ZBTB41 EZH2 knockdown Colon HCT116 0.466682 -1.09949 0.025333989 0.8488990 DataSet_03_334
ZBTB41 ARID3B CRISPR Colon HCT15 1.74309 0.80165 - - DataSet_03_335
ZBTB41 EZH2 shRNA Mammary_gland LM2 1.55865 0.640301 1.473869e-02 1.918767e-01 DataSet_03_350
ZBTB41 CREBBP CRISPR Brain U5-NPC 1.72188 0.783984 0.2558852765 0.7490853 DataSet_03_356
ZBTB41 PTPN14 CRISPR Brain U5-NPC 2.01815 1.01303 7.589583e-02 0.30169908 DataSet_03_357
ZBTB41 TP53 CRISPR Brain U5-NPC 1.97281 0.980249 3.433036e-02 1.684526e-01 DataSet_03_358
ZBTB41 MYC siRNA Peripheral_blood T lymphocyte 1.67978 0.748273 4.173186e-02 0.183453737 DataSet_03_363
ZBTB41 DNMT3A knockout Embryo_kidney HEK293T 0.233341 -2.09949 - - DataSet_03_369
ZBTB41 ZFP36L1 siRNA Urinary_bladder J82 3.01892 1.59403 - - DataSet_03_371
ZBTB41 GLI1 siRNA Skeletal_muscle RMS13 2.33955 1.22623 1.767877e-02 0.105085726 DataSet_03_375
ZBTB41 ZNF213 siRNA Mammary_gland MCF7 0.605107 -0.724739 7.602419e-01 9.052723e-01 DataSet_03_376
ZBTB41 ZBTB7A siRNA Stomach BGC823 0.61191 -0.708608 - - DataSet_03_380
ZBTB41 NFKB2 siRNA Bone_marrow U2OS 1.99153 0.993874 9.268262e-02 0.35580127 DataSet_03_381
ZBTB41 TCF19 CRISPR Oral_squamous CAL27 0.452547 -1.14386 1.003591e-01 0.3294087206 DataSet_03_383
ZBTB41 YY1 shRNA Brain GSC1517 0.524272 -0.931613 - - DataSet_03_384
ZBTB41 TRIM8 siRNA Mammary_gland MCF7 0.618702 -0.692683 1.624635e-03 0.0166612908 DataSet_03_388
ZBTB41 ILF2 siRNA Stomach SGC-7901 4.79851 2.26259 0.0506199155 0.16050194 DataSet_03_393
ZBTB41 ASXL1 CRISPR Embryo iPSC 0.419511 -1.25322 0.0269746520 0.8048302 DataSet_03_394
ZBTB41 BMI1 shRNA Bile_duct QBC-939 3.07268 1.6195 4.797564e-06 0.0006498347 DataSet_03_395
ZBTB41 SUMO1 CRISPR Bone_marrow U2OS 0.541063 -0.886132 2.094019e-02 8.550637e-02 DataSet_03_401
ZBTB41 TFAP2A knockout Embryo H9 2.05088 1.03624 6.175363e-03 0.05346318 DataSet_03_405
ZBTB41 CHD1 shRNA Prostate LNCaP 0.535299 -0.901583 4.523842e-03 1.502800e-01 DataSet_03_407
ZBTB41 USP22 shRNA Liver HuH7 6.01624 2.58886 - - DataSet_03_411
ZBTB41 E2F6 shRNA Liver HuH7 0.325283 -1.62023 - - DataSet_03_412
ZBTB41 FOXK2 shRNA Ovary OVCAR-5 2.84967 1.5108 4.627150e-02 0.17543264 DataSet_03_419
ZBTB41 USP7 shRNA Skin xenograft cells 0.492052 -1.02312 0.26970731 0.4348960 DataSet_03_431
ZBTB41 PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.650964 -0.619351 - - DataSet_03_432
ZBTB41 SUFU shRNA Mammary_gland HCC1954 cells 0.442916 -1.17489 0.0576331277 0.5464194 DataSet_03_437
ZBTB41 HMG20A siRNA Mammary_gland MDA-MB-231 1.8209 0.864648 0.1063317542 0.3391180 DataSet_03_442
ZBTB41 PHF14 siRNA Mammary_gland MDA-MB-231 1.69001 0.757033 0.1343322745 0.5753026 DataSet_03_443
ZBTB41 PURA siRNA Cervix HeLa 1.75019 0.80751 1.390792e-02 0.109273050 DataSet_03_444
ZBTB41 FOSL1 siRNA Prostate MSKPCa3 0.60693 -0.720397 0.0177112080 0.3378437 DataSet_03_445
ZBTB41 CAMTA1 knockout Embryo_kidney HEK293T 1.99048 0.993114 1.368511e-02 0.11693143 DataSet_03_448
ZBTB41 PPARG siRNA Aortic_valve Valvular endothelial cell 1.52251 0.606451 2.224543e-05 2.733072e-03 DataSet_03_456
ZBTB41 SREBF2 siRNA Umbilical_vein HUVEC 1.63268 0.707246 2.639248e-06 1.848293e-03 DataSet_03_457
ZBTB41 ARID1A shRNA Bile_duct MMNK1 1.50007 0.585033 9.302182e-03 0.093834540 DataSet_03_458
ZBTB41 TXNIP shRNA Cord_Blood CD34+ cells 1.97263 0.980119 - - DataSet_03_461
ZBTB41 TXNIP shRNA Cord_blood ST3 1.6686 0.738642 4.569944e-02 0.2847775415 DataSet_03_462
ZBTB41 SOX9 knockout Liver HuH7 0.610841 -0.71113 3.220779e-03 1.955866e-02 DataSet_03_463
ZBTB41 PARP1 knockout Embryo_kidney HEK293a 2.75241 1.4607 6.166066e-13 1.330616e-10 DataSet_03_464
ZBTB41 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 1.71462 0.777887 - - DataSet_03_467
ZBTB41 SMARCA1 shRNA Embryo_kidney HEK293T 0.642111 -0.639105 - - DataSet_03_468
ZBTB41 WHSC1 siRNA Prostate PC3 0.504823 -0.98615 3.240442e-03 0.08006188 DataSet_03_471
ZBTB41 EZH2 siRNA Prostate LNCaP 1.62749 0.70265 - - DataSet_03_472
Regulation Region
 
T(co)Fs that significantly regulate MCM2 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of ZBTB41
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines