Gene Overview
Target Gene: ZC3HAV1L
NCBI Official Symbol: ZC3HAV1L
Entrez ID: 92092
Ensembl ID: ENSG00000146858
Gene Full Name: zinc finger CCCH-type containing, antiviral 1 like
Strand: -
Gene Locus: 7q34
External Links:

ZC3HAV1L Significantly Regulated by These T(co)Fs

T(co)Fs that Activate ZC3HAV1L   
T(co)Fs that Repress ZC3HAV1L
The Intensity of the Gene Regulated by T(co)Fs:
ZC3HAV1L-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
ZC3HAV1L MYB shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 0.64667 -0.62889 9.9331e-06 7.69899e-05 DataSet_01_102
ZC3HAV1L FOXM1 siRNA Central_nervous_system U87 0.3831 -1.3842 - - DataSet_01_122
ZC3HAV1L ZNF100 siRNA Gastrointestinal_tissue GIST-T1 0.66129 -0.59664 0.00059 0.01672 DataSet_01_124
ZC3HAV1L ZNF85 siRNA Gastrointestinal_tissue GIST-T1 0.47189 -1.08347 5.37446e-06 0.00103 DataSet_01_126
ZC3HAV1L ZNF431 siRNA Gastrointestinal_tissue GIST-T1 0.65716 -0.60569 0.00053 0.00553 DataSet_01_128
ZC3HAV1L TAL1 shRNA Umbilical_cord_blood ECFCs 0.50356 -0.98976 0.01209 0.38527 DataSet_01_152
ZC3HAV1L ELK1 siRNA Peripheral_blood CD4+ T cells 2.35892 1.23813 9.46016e-06 0.00074 DataSet_01_162
ZC3HAV1L JUN siRNA Peripheral_blood CD4+ T cells 2.0447 1.03189 8.76812e-06 0.001 DataSet_01_164
ZC3HAV1L NFATC3 siRNA Peripheral_blood CD4+ T cells 424.125 8.72835 0.05089 0.23651 DataSet_01_166
ZC3HAV1L TP53 siRNA Lung SAECs 1.60142 0.67935 0.43905 0.78038 DataSet_01_175
ZC3HAV1L GABPA shRNA Prostate C4-2B 1882.23 10.8782 0.23463 0.43934 DataSet_01_190
ZC3HAV1L GABPA shRNA Prostate LNCaP 1151.98 10.1699 0.46146 0.7048 DataSet_01_191
ZC3HAV1L TP63 siRNA Immortalized_keratinocyte HaCaT RG 0.65002 -0.62145 - - DataSet_01_197
ZC3HAV1L TP63 siRNA Head_and_neck SCC-012 1.66691 0.73718 - - DataSet_01_201
ZC3HAV1L XBP1 shRNA Mammary_gland MDA-MB-231 0.5631 -0.82854 0.00019 0.0075 DataSet_01_204
ZC3HAV1L MITF shRNA Skin COLO829 0.59909 -0.73916 0.00022 0.00914 DataSet_01_207
ZC3HAV1L FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 0.2444 -2.03269 - - DataSet_01_209
ZC3HAV1L LIN28A siRNA Embryo H9 2.75783 1.46353 0.00014 0.00373 DataSet_01_215
ZC3HAV1L EGR2 siRNA Neuroepithelium SK-N-MC 0.65026 -0.62091 0.01578 0.5876 DataSet_01_243
ZC3HAV1L ZIC5 siRNA Skin A375 0.36371 -1.45915 - - DataSet_01_284
ZC3HAV1L ZIC5 siRNA Skin SK-MEL-28 0.42324 -1.24045 - - DataSet_01_285
ZC3HAV1L JUN siRNA Mammary_gland BT549 1.69747 0.76338 4.69736e-05 0.00098 DataSet_01_291
ZC3HAV1L TFAP4 siRNA Brain BE(2)-C 0.17542 -2.51114 0.25055 0.51625 DataSet_01_295
ZC3HAV1L MYCN siRNA Brain BE(2)-C 0.5432 -0.88045 0.73915 1 DataSet_01_296
ZC3HAV1L PTEN shRNA Skin A431 1.52271 0.60664 0.06645 0.21153 DataSet_01_301
ZC3HAV1L PTEN shRNA Lung HCC827 1.81733 0.86182 0.00949 0.42424 DataSet_01_302
ZC3HAV1L SOX9 siRNA Prostate VCaP 0.62334 -0.68192 0.08618 0.9316 DataSet_01_308
ZC3HAV1L SOX9 siRNA Prostate VCaP 0.62334 -0.68192 0.08618 0.9316 DataSet_01_309
ZC3HAV1L ELK3 shRNA Mammary_gland MDA-MB-231 0.15798 -2.6622 3.06938e-05 0.00026 DataSet_01_318
ZC3HAV1L FOXO1 shRNA Haematopoietic_and_lymphoid_tissue RS4;11 1.57038 0.65111 0.00379 0.05361 DataSet_01_321
ZC3HAV1L SAFB2 shRNA Liver HepG2 0.52221 -0.93729 0.00409 0.0284 DataSet_02_102
ZC3HAV1L SSB shRNA Liver HepG2 0.35369 -1.49943 0.00413 0.01539 DataSet_02_107
ZC3HAV1L ZNF622 shRNA Liver HepG2 0.558 -0.84167 0.00154 0.01013 DataSet_02_108
ZC3HAV1L HNRNPUL1 shRNA Liver HepG2 0.38796 -1.36603 0.00086 0.01994 DataSet_02_109
ZC3HAV1L GTF2F1 shRNA Liver HepG2 0.58007 -0.7857 0.01397 0.23107 DataSet_02_110
ZC3HAV1L RBM39 shRNA Liver HepG2 0.42188 -1.24511 0.08614 0.30877 DataSet_02_111
ZC3HAV1L U2AF2 shRNA Liver HepG2 0.50625 -0.98208 0.04636 0.138 DataSet_02_113
ZC3HAV1L PCBP2 shRNA Liver HepG2 0.64947 -0.62267 0.01721 0.09686 DataSet_02_123
ZC3HAV1L SNRNP70 shRNA Liver HepG2 0.6129 -0.70627 0.03581 0.09904 DataSet_02_126
ZC3HAV1L SRSF3 shRNA Liver HepG2 0.46334 -1.10985 0.00966 0.08325 DataSet_02_127
ZC3HAV1L GATA2 siRNA Uterus Decidual stromal cells 0.665717 -0.587019 0.217243742004066 0.821413753809329 DataSet_03_100
ZC3HAV1L GATA2 siRNA Lymph Lymphatic endothelial cells 1.57682 0.657021 0.00031895397381811 0.00170193270161498 DataSet_03_101
ZC3HAV1L HMGA1 siRNA Mammary_gland MDA-MB-231 0.534351 -0.90414 2.64975650267106e-08 1.85697336781041e-06 DataSet_03_124
ZC3HAV1L Klf4 siRNA Skin Primary neonatal keratinocytes 1.67705 0.745929 0.000863017668289376 0.00834314625303859 DataSet_03_147
ZC3HAV1L KLF5 siRNA Stomach KatoIII 0.349842 -1.51522 0.0725782368692383 0.491611423022632 DataSet_03_150
ZC3HAV1L MITF siRNA Skin Ma-Mel-15 0.594857 -0.749384 0.02905582785619 0.338275177835911 DataSet_03_166
ZC3HAV1L SP1 siRNA Mammary_gland MDA-MB-231 0.330737 -1.59625 0.133292203484862 0.413972819854456 DataSet_03_250
ZC3HAV1L STAT6 siRNA Umbilical_vein HUVEC 1.89942 0.925557 0.0218539062566665 0.602026045432566 DataSet_03_264
ZC3HAV1L TP63 siRNA Skin Primary neonatal keratinocytes 1.65961 0.730842 0.0129344371792476 0.0580869425791385 DataSet_03_281
ZC3HAV1L NFX1 CRISPR Liver HepG2 0.562923 -0.828991 0.011275442485849 0.0390159376671994 DataSet_04_032
ZC3HAV1L SMAD5 CRISPR Liver HepG2 0.645429 -0.631669 0.00718965848599098 0.367798690114644 DataSet_04_036
ZC3HAV1L CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.66667 1.41504 0.697982609885192 0.860954882305076 DataSet_02_38
ZC3HAV1L HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.52632 0.610053 0.670810617846023 0.894409163308005 DataSet_02_75
ZC3HAV1L HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 18.6667 4.22239 0.0797877263699686 0.555117045826504 DataSet_02_45
ZC3HAV1L NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 5 2.32193 0.491112234758848 0.704108541254071 DataSet_02_32
ZC3HAV1L TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.66667 0.736966 0.877457446781999 0.945336359304645 DataSet_02_43
ZC3HAV1L TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 5.33333 2.41504 0.26334458207897 0.430408445257075 DataSet_02_53
ZC3HAV1L HDAC5 siRNA Liver human hepatocytes 1.6979 0.76375 3.571727e-04 4.618105e-03 DataSet_03_346
ZC3HAV1L PRMT1 shRNA Lung A549 1.9549 0.967093 - - DataSet_03_342
ZC3HAV1L AEBP1 siRNA Central_nervous_system U87MG 1.81587 0.860664 8.160677e-02 0.9999434 DataSet_03_338
ZC3HAV1L ARID3B CRISPR Colon HCT15 0.464024 -1.10773 - - DataSet_03_335
ZC3HAV1L TET1 CRISPR Mammary_gland MDA-MB-231 0.567948 -0.81617 6.269593e-03 4.498154e-02 DataSet_03_347
ZC3HAV1L ESR1 siRNA Mammary_gland MCF7 1.96436 0.97406 7.815369e-05 0.0085615274 DataSet_03_352
ZC3HAV1L TET1 CRISPR Mammary_gland Hs578T 8.73089 3.12613 8.269603e-05 3.743917e-03 DataSet_03_355
ZC3HAV1L CREBBP CRISPR Brain U5-NPC 1.87546 0.907243 0.2637264507 0.7490853 DataSet_03_356
ZC3HAV1L PTPN14 CRISPR Brain U5-NPC 0.657518 -0.604898 1.878111e-01 0.42410694 DataSet_03_357
ZC3HAV1L TP53 CRISPR Brain U5-NPC 1.97802 0.984058 6.144310e-02 1.973605e-01 DataSet_03_358
ZC3HAV1L RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 2.27801 1.18777 1.190644e-02 1.509810e-01 DataSet_03_359
ZC3HAV1L ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 0.559352 -0.838173 2.227271e-02 4.582969e-02 DataSet_03_362
ZC3HAV1L TP53 knockout Stomach SNU1 1.72051 0.78284 0.2225215442 0.9301241 DataSet_03_365
ZC3HAV1L USP22 shRNA Liver PLC_PRF_5 cells 0.451572 -1.14697 1.427093e-02 0.13136554 DataSet_03_368
ZC3HAV1L DNMT3A knockout Embryo_kidney HEK293T 2.67505 1.41957 - - DataSet_03_369
ZC3HAV1L E2F1 siRNA Nasopharynx HK1 2 1 3.571404e-01 9.722824e-01 DataSet_03_373
ZC3HAV1L EZH2 CRISPR Ovary SKOV3 0.530387 -0.914883 8.764311e-02 0.2544886252 DataSet_03_378
ZC3HAV1L ZBTB7A siRNA Stomach BGC823 0.47596 -1.07109 - - DataSet_03_380
ZC3HAV1L YY1 knockdown Liver HepG2 0.567383 -0.817606 2.705758e-03 1.174299e-02 DataSet_03_390
ZC3HAV1L ILF2 siRNA Stomach SGC-7901 2.37302 1.24672 0.0038082263 0.02546153 DataSet_03_393
ZC3HAV1L TLE4 CRISPR Lymph CAR T Cell 1.88126 0.911697 1.012446e-03 0.07492319 DataSet_03_398
ZC3HAV1L RELA CRISPR Brain T30 1.66819 0.738282 0.1524886350 0.8400824 DataSet_03_399
ZC3HAV1L TFAP2A knockout Embryo H9 128.444 7.005 7.214809e-05 0.01552045 DataSet_03_405
ZC3HAV1L USP22 shRNA Liver HuH7 2.09153 1.06456 - - DataSet_03_411
ZC3HAV1L FOXK2 shRNA Ovary OVCAR-5 0.36 -1.47393 3.489222e-02 0.15204805 DataSet_03_419
ZC3HAV1L MAEL CRISPR Liver Alexander cells 0.560268 -0.835811 - - DataSet_03_423
ZC3HAV1L USP7 shRNA Skin xenograft cells 0.404074 -1.30731 0.25665192 0.4348960 DataSet_03_431
ZC3HAV1L DAXX shRNA Mammary_gland MDA-MB-231 2.2299 1.15698 4.224492e-01 0.70942351 DataSet_03_441
ZC3HAV1L PURA siRNA Cervix HeLa 1.52197 0.605941 6.112339e-03 0.077993043 DataSet_03_444
ZC3HAV1L CAMTA1 knockout Embryo_kidney HEK293T 2.43059 1.28131 4.420388e-03 0.08959112 DataSet_03_448
ZC3HAV1L CBX2 siRNA Mammary_gland MDA-MB-231 1.77912 0.831165 6.411743e-04 6.709030e-03 DataSet_03_450
ZC3HAV1L CBX2 siRNA Mammary_gland MCF7 2.00018 1.00013 6.176107e-04 0.0040713554 DataSet_03_451
ZC3HAV1L OGT siRNA Embryo BeWo cells 0.571429 -0.807355 6.862721e-01 0.90145377 DataSet_03_453
ZC3HAV1L SMARCA2 shRNA Lung HCC2302 0.509313 -0.973377 6.007415e-12 7.608041e-11 DataSet_03_455
ZC3HAV1L ARID1A shRNA Bile_duct MMNK1 0.641528 -0.640416 1.748138e-02 0.134089554 DataSet_03_458
ZC3HAV1L IRF2 shRNA Cord_Blood CD34+ cells 1.87879 0.909802 - - DataSet_03_460
ZC3HAV1L TXNIP shRNA Cord_Blood CD34+ cells 2.5 1.32193 - - DataSet_03_461
ZC3HAV1L TXNIP shRNA Cord_blood ST3 0.545455 -0.874469 6.419368e-01 0.7795741300 DataSet_03_462
ZC3HAV1L SOX9 knockout Liver HuH7 0.622966 -0.682775 3.675069e-03 2.139960e-02 DataSet_03_463
ZC3HAV1L SMARCA1 Cas13 Embryo_kidney HEK293T 0.196013 -2.35098 - - DataSet_03_466
ZC3HAV1L SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 1.5814 0.661198 - - DataSet_03_467
ZC3HAV1L SMARCA1 shRNA Embryo_kidney HEK293T 0.22093 -2.17834 - - DataSet_03_468
ZC3HAV1L EZH2 siRNA Prostate LNCaP 4.09357 2.03336 - - DataSet_03_472
ZC3HAV1L EZH2 siRNA Prostate LNCaP 0.569832 -0.81139 2.952685e-01 1.0000000 DataSet_03_475
Regulation Region
 
T(co)Fs that significantly regulate TFAP2A by the evidences of both expression and ChIP-seq/motif
Expression Atlas of ZC3HAV1L
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines