Gene Overview
Target Gene: APOF
NCBI Official Symbol: APOF
Entrez ID: 319
Ensembl ID: ENSG00000175336
Gene Full Name: apolipoprotein F
Strand: -
Gene Locus: 12q13.3
External Links:

APOF Significantly Regulated by These T(co)Fs

T(co)Fs that Activate APOF   
T(co)Fs that Repress APOF
The Intensity of the Gene Regulated by T(co)Fs:
APOF-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
APOF ID1 siRNA Lung A549 1.75872 0.81453 0.14488 0.37496 DataSet_01_117
APOF ZIC2 siRNA Pancreas PANC1 1.68299 0.75103 - - DataSet_01_121
APOF FOXM1 siRNA Central_nervous_system U87 0.55473 -0.85015 - - DataSet_01_122
APOF HSF1 shRNA Skin A375 0.63077 -0.66482 0.34713 0.6102 DataSet_01_155
APOF ETV1 shRNA Prostate LNCaP 0.57227 -0.80523 3.89995e-05 0.00047 DataSet_01_161
APOF TP63 siRNA Immortalized_keratinocyte HaCaT RG 0.29412 -1.76553 - - DataSet_01_196
APOF TP63 siRNA Head_and_neck SCC-1 8.7 3.12102 - - DataSet_01_198
APOF TP63 siRNA Immortalized_keratinocyte HaCaT 0.15524 -2.68741 - - DataSet_01_200
APOF TP63 siRNA Head_and_neck SCC-012 0.31392 -1.67151 - - DataSet_01_201
APOF TP63 siRNA Head_and_neck SCC-6 0.6358 -0.65335 - - DataSet_01_202
APOF FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 15.3556 3.94069 - - DataSet_01_208
APOF FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 0.28125 -1.83008 - - DataSet_01_209
APOF FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.09955 -3.32843 - - DataSet_01_210
APOF KLF2 shRNA Bone_marrow RPMI8226 1.6626 0.73344 0.10025 0.70916 DataSet_01_226
APOF SOX4 shRNA Mammary_gland MDA-MB-231 1.54708 0.62954 0.27747 0.5995 DataSet_01_260
APOF AR shRNA Prostate CWR22Pc 0.36153 -1.46782 0.00025 0.00765 DataSet_01_278
APOF STAT5 shRNA Prostate CWR22Pc 0.61713 -0.69636 0.0112 0.05638 DataSet_01_279
APOF POSTN shRNA Brain GSC272 1.50969 0.59425 0.81614 0.92336 DataSet_01_293
APOF TFAP4 siRNA Brain BE(2)-C 0.22077 -2.17936 0.35588 0.51625 DataSet_01_295
APOF SOX7 siRNA Umbilical_vein HUVEC 1.56479 0.64597 0.1149 0.89788 DataSet_01_299
APOF SOX17 siRNA Umbilical_vein HUVEC 0.58597 -0.7711 0.09359 0.99998 DataSet_01_300
APOF PTEN shRNA Lung HCC827 0.50372 -0.9893 0.7321 0.91626 DataSet_01_302
APOF SOX9 siRNA Prostate VCaP 1.82584 0.86856 0.34011 0.93949 DataSet_01_308
APOF SOX9 siRNA Prostate VCaP 1.82584 0.86856 0.34011 0.93949 DataSet_01_309
APOF HOXC6 siRNA Prostate LNCaP 10.2453 3.35689 0.00437 0.96954 DataSet_01_333
APOF ZNF24 siRNA Embryo_kidney HEK293 1.57336 0.65385 - - DataSet_01_353
APOF SOX17 siRNA Umbilical_vein HUVEC 0.58839 -0.76515 - - DataSet_01_360
APOF RBM17 shRNA Liver HepG2 0.51465 -0.95833 0.11334 0.37564 DataSet_02_100
APOF SAFB2 shRNA Liver HepG2 2.68539 1.42513 0.00034 0.02192 DataSet_02_102
APOF FIP1L1 shRNA Liver HepG2 0.2968 -1.75245 0.00088 0.01394 DataSet_02_103
APOF U2AF2 shRNA Liver HepG2 1.85994 0.89526 0.73111 0.8224 DataSet_02_105
APOF TAF15 shRNA Liver HepG2 0.53296 -0.9079 0.00102 0.01147 DataSet_02_106
APOF SSB shRNA Liver HepG2 0.25578 -1.96702 2e-04 0.00428 DataSet_02_107
APOF RBM39 shRNA Liver HepG2 0.59504 -0.74894 0.20525 0.45576 DataSet_02_111
APOF BCLAF1 shRNA Liver HepG2 3.02219 1.59559 0.00039 0.02408 DataSet_02_112
APOF PCBP1 shRNA Liver HepG2 0.36875 -1.4393 0.00059 0.01339 DataSet_02_115
APOF TARDBP shRNA Liver HepG2 2.44008 1.28693 0.01778 0.05234 DataSet_02_116
APOF RBM25 shRNA Liver HepG2 0.44055 -1.18261 0.00034 0.02139 DataSet_02_119
APOF PTBP1 shRNA Liver HepG2 0.36786 -1.44276 1e-04 0.00582 DataSet_02_120
APOF EWSR1 shRNA Liver HepG2 0.55611 -0.84657 0.004 0.04665 DataSet_02_122
APOF PCBP2 shRNA Liver HepG2 0.5241 -0.9321 0.00114 0.04878 DataSet_02_123
APOF HNRNPLL shRNA Liver HepG2 4.59528 2.20015 0.00343 0.01956 DataSet_02_125
APOF PRPF4 shRNA Liver HepG2 1.59224 0.67106 0.01947 0.07482 DataSet_02_128
APOF AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.6 0.67807 0.20819 0.37309 DataSet_02_132
APOF DROSHA shRNA Haematopoietic_and_lymphoid_tissue K562 2.33333 1.22239 0.9256 0.98064 DataSet_02_145
APOF CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.44444 -1.16993 0.30864 0.69664 DataSet_02_146
APOF FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.2 -2.32193 0.30038 0.44759 DataSet_02_147
APOF SRSF4 shRNA Haematopoietic_and_lymphoid_tissue K562 0.375 -1.41504 0.08131 0.4085 DataSet_02_154
APOF GTF2F1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 1 1 DataSet_02_157
APOF XRCC5 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 1 1 DataSet_02_159
APOF HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 7.25 2.85798 0.00216 0.11467 DataSet_02_160
APOF SUB1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 1 1 DataSet_02_161
APOF SSB shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 1 1 DataSet_02_164
APOF ZFX siRNA Prostate C4-2B 2.07752 1.05486 0.01114 0.03386 DataSet_02_172
APOF NFE2L2 siRNA Haematopoietic_and_lymphoid_tissue K562 1.83333 0.87447 0.24856 1 DataSet_02_174
APOF LMNA siRNA Haematopoietic_and_lymphoid_tissue K562 0.28571 -1.80735 0.83863 1 DataSet_02_175
APOF CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 0.11111 -3.16993 0.77857 1 DataSet_02_176
APOF VEZF1 siRNA Haematopoietic_and_lymphoid_tissue K562 3.5 1.80735 0.96003 1 DataSet_02_179
APOF ZMIZ1 siRNA Haematopoietic_and_lymphoid_tissue K562 3.66667 1.87447 0.07704 1 DataSet_02_181
APOF MAFK siRNA Haematopoietic_and_lymphoid_tissue K562 0.14286 -2.80735 0.42751 1 DataSet_02_183
APOF KAT2B siRNA Haematopoietic_and_lymphoid_tissue K562 2.6 1.37851 0.73483 1 DataSet_02_184
APOF BACH1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.03704 -4.75489 0.42114 1 DataSet_02_188
APOF MAFG siRNA Haematopoietic_and_lymphoid_tissue K562 0.59259 -0.75489 0.57257 1 DataSet_02_189
APOF RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 2.30303 1.20353 0.83298 1 DataSet_02_190
APOF LMNB2 siRNA Haematopoietic_and_lymphoid_tissue K562 1.71429 0.77761 0.31335 1 DataSet_02_191
APOF MAX siRNA Haematopoietic_and_lymphoid_tissue K562 1.62963 0.70454 0.47789 1 DataSet_02_192
APOF TCP1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.71429 0.77761 0.78907 1 DataSet_02_194
APOF LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.11111 -3.16993 0.78226 1 DataSet_02_195
APOF CHD2 siRNA Haematopoietic_and_lymphoid_tissue K562 5 2.32193 0.16601 0.28569 DataSet_02_196
APOF CDAN1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.22222 -2.16993 0.9322 1 DataSet_02_197
APOF UBTF siRNA Haematopoietic_and_lymphoid_tissue K562 5.33333 2.41504 0.44502 1 DataSet_02_198
APOF TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.33333 1.22239 0.20904 1 DataSet_02_201
APOF BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.83333 1.5025 0.28177 1 DataSet_02_202
APOF RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.28571 1.19265 0.26687 1 DataSet_02_204
APOF E2F6 siRNA Haematopoietic_and_lymphoid_tissue K562 0.25926 -1.94753 0.8714 1 DataSet_02_205
APOF ZFX siRNA Mammary_gland MCF7 4 2 0.57784 0.76196 DataSet_02_206
APOF AR siRNA Prostate LNCaP 0.425317 -1.23339 0.0834061288235539 1 DataSet_03_005
APOF BCL6 siRNA Lymph OCI-Ly7 DLBCL 0.295821 -1.7572 0.034753653487337 0.677892927235962 DataSet_03_025
APOF BCL6 siRNA Lymph Pfeiffer DLBCL 1.66441 0.735009 0.466244256252689 0.829786512175877 DataSet_03_026
APOF CEBPB siRNA Embryo hESC 0.616759 -0.697221 0.28947150833803 0.664645651715571 DataSet_03_049
APOF FOXA1 siRNA Prostate LNCaP 0.652407 -0.616156 2.69499929662e-07 2.55452833385741e-05 DataSet_03_083
APOF GATA2 siRNA Uterus Decidual stromal cells 2.11731 1.08223 0.0790838094965597 0.703332532348739 DataSet_03_100
APOF GATA6 siRNA Stomach AGS 0.599442 -0.738307 0.575306288888374 0.895145593188157 DataSet_03_108
APOF IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 3.51671 1.81423 0.407687150739063 0.999948959532916 DataSet_03_134
APOF KLF5 siRNA Stomach AGS 0.597423 -0.743174 0.50960560872538 0.843974676923717 DataSet_03_149
APOF KLF5 siRNA Stomach YCC3 1.5083 0.592919 0.581720647598489 0.840667461931779 DataSet_03_151
APOF MEF2D shRNA Liver HuH7 1.61943 0.695482 - - DataSet_03_162
APOF MEF2D siRNA Liver HuH7 7.37735 2.8831 - - DataSet_03_163
APOF MITF siRNA Skin Ma-Mel-15 0.635032 -0.655099 0.208156414801744 0.67033278344492 DataSet_03_166
APOF MITF siRNA Skin SK-MEL-5 0.590345 -0.760371 0.0010413000532087 0.00349602907497414 DataSet_03_168
APOF NR2F2 siRNA Uterus Primary eutopic stromal cells 1.53429 0.617573 0.23344863899472 0.99947668859931 DataSet_03_202
APOF SOX11 siRNA Lung_fibroblast NHLF 0.497119 -1.00834 0.240382116957335 0.610530511867534 DataSet_03_238
APOF SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 1.79545 0.844349 - - DataSet_03_246
APOF SP1 siRNA Mammary_gland MDA-MB-231 0.555209 -0.848896 0.153320491830419 0.413972819854456 DataSet_03_250
APOF SP1 siRNA Ovary OVSAYO 1.90323 0.928449 0.0394728161756936 0.243761302893612 DataSet_03_251
APOF STAT1 knockout Liver Huh-7.5 7.24606 2.8572 1.89587019671051e-08 9.84335806132095e-05 DataSet_03_257
APOF STAT6 siRNA Umbilical_vein HUVEC 2.29032 1.19555 0.490555829719684 0.915740310833557 DataSet_03_264
APOF TFE3 siRNA Kidney UOK257-2 0.402436 -1.31317 - - DataSet_03_275
APOF APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 4.5 2.16992 0.136974963874017 0.652057106453001 DataSet_04_001
APOF YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.243902 -2.03562 0.0097048320065038 0.428585467358289 DataSet_04_022
APOF NFX1 CRISPR Liver HepG2 0.557464 -0.843048 0.0537161764492285 0.106802445567776 DataSet_04_032
APOF SMAD4 CRISPR Liver HepG2 0.427627 -1.22558 0.000273126397827516 0.0527443981287996 DataSet_04_035
APOF ZC3H8 shRNA Liver HepG2 2.32642 1.21811 0.00875383276111727 0.0991889983384463 DataSet_04_040
APOF CNOT7 CRISPR Liver HepG2 1.80591 0.852726 9.82221267845949e-05 0.0103439741888259 DataSet_04_045
APOF PAN2 CRISPR Liver HepG2 0.427627 -1.22558 3.4844781189862e-05 0.0134929239906341 DataSet_04_066
APOF CALR shRNA Liver HepG2 3.43333 1.77961 1.36373278354247e-05 0.00191058974100696 DataSet_04_053
APOF CCAR1 shRNA Liver HepG2 0.371102 -1.43011 0.000111135212822204 0.00860913704335324 DataSet_04_054
APOF PRPF6 shRNA Liver HepG2 0.219457 -2.18799 1.83790037126759e-05 0.0210821866264412 DataSet_04_056
APOF UBE2L3 shRNA Liver HepG2 2.13122 1.09168 0.000208669801176854 0.00683023679343057 DataSet_04_055
APOF CNOT3 shRNA Lung A549 0.65548 -0.609376 6.583985e-01 0.9548705 DataSet_03_340
APOF YBX1 siRNA Prostate LNCaP 2.6868 1.42589 4.244802e-08 9.649404e-05 DataSet_03_322
APOF SNAI2 shRNA Pancreas KLM1 0.529708 -0.916732 7.878794e-03 0.15697502 DataSet_03_307
APOF AEBP1 siRNA Central_nervous_system U87MG 1.80313 0.850503 2.678604e-01 0.9999434 DataSet_03_338
APOF EZH2 shRNA Mammary_gland LM2 2.41957 1.27475 5.638161e-01 8.655404e-01 DataSet_03_350
APOF SKI CRISPR Blood HL60 4 2 2.649575e-01 0.615851377 DataSet_03_351
APOF ESR1 siRNA Mammary_gland MCF7 1.64045 0.714094 8.481399e-02 0.2526388664 DataSet_03_352
APOF PARP1 siRNA Prostate LNCaP 1.64894 0.721542 6.756478e-01 0.848771495 DataSet_03_354
APOF TET1 CRISPR Mammary_gland Hs578T 0.532108 -0.910209 4.062174e-01 5.977075e-01 DataSet_03_355
APOF TP53 CRISPR Brain U5-NPC 3 1.58496 2.904110e-01 4.186666e-01 DataSet_03_358
APOF RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 0.640463 -0.642813 7.532544e-01 8.923726e-01 DataSet_03_359
APOF MYC siRNA Peripheral_blood T lymphocyte 3.21156 1.68327 3.342197e-01 0.607689190 DataSet_03_363
APOF USP22 shRNA Liver PLC_PRF_5 cells 0.211382 -2.24207 6.807187e-02 0.24825251 DataSet_03_368
APOF TPR shRNA Bone_marrow U2OS 3.376 1.75531 5.039454e-01 8.646248e-01 DataSet_03_370
APOF GLI1 siRNA Skeletal_muscle RMS13 2.10405 1.07317 7.018280e-02 0.220950934 DataSet_03_375
APOF DNMT1 siRNA Skin Human melanoma cells 1.65333 0.725379 2.299161e-01 3.269845e-01 DataSet_03_382
APOF KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 0.521303 -0.939805 0.6587996875 0.9326193 DataSet_03_387
APOF TRIM8 siRNA Mammary_gland MCF7 3 1.58496 5.730015e-01 0.7345455117 DataSet_03_388
APOF JAZF1 siRNA Cervix HeLa Kyoto 2.10252 1.07212 5.708975e-02 0.668320798 DataSet_03_396
APOF IKZF2 CRISPR Lymph CAR T Cell 2.22202 1.15187 1.163186e-01 0.564989512 DataSet_03_397
APOF EHF shRNA Stomach MKN7 0.00106876 -9.86985 - - DataSet_03_402
APOF E2F1 siRNA Prostate LNCaP 1.78351 0.834715 6.151826e-02 0.5697977484 DataSet_03_413
APOF CIC knockout Brain Immortalized Astrocyte Cells 0.625 -0.678072 8.911710e-02 4.978029e-01 DataSet_03_438
APOF FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 2.125 1.08746 1.006655e-01 0.90558273 DataSet_03_439
APOF FOSL1 siRNA Prostate MSKPCa3 0.285714 -1.80736 0.6310712031 0.7942548 DataSet_03_445
APOF RELB CRISPR Colon SW480 5 2.32193 2.706500e-02 1.343620e-01 DataSet_03_449
APOF ZFP36L1 CRISPR Lung NCI-H1876 2.4381 1.28576 4.527864e-01 0.992381486 DataSet_03_454
APOF IRF2 shRNA Cord_Blood CD34+ cells 9 3.16992 - - DataSet_03_460
APOF SOX9 knockout Liver HuH7 0.461538 -1.11548 2.094100e-02 7.375060e-02 DataSet_03_463
APOF PARP1 knockout Embryo_kidney HEK293a 2 1 6.366365e-01 7.296632e-01 DataSet_03_464
APOF LIN28A siRNA Mammary_gland MCF7M 2.47862 1.30954 9.696493e-02 0.4189417 DataSet_03_469
APOF LIN28A siRNA Mammary_gland MCF7M 2.47862 1.30954 9.696493e-02 0.4189417 DataSet_03_470
APOF APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 4.5 2.16992 0.3084256 0.744442 DataSet_04_072
Regulation Region
 
T(co)Fs that significantly regulate HOXC6 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of APOF
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines