Gene Overview
Target Gene: ATF3
NCBI Official Symbol: ATF3
Entrez ID: 467
Ensembl ID: ENSG00000162772
Gene Full Name: activating transcription factor 3
Strand: +
Gene Locus: 1q32.3
External Links:

ATF3 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate ATF3   
T(co)Fs that Repress ATF3
The Intensity of the Gene Regulated by T(co)Fs:
ATF3-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
ATF3 IRF6 shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 1.82101 0.86474 0.00011 0.0056 DataSet_01_101
ATF3 MYB shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 1.87721 0.90859 1.91902e-07 3.78629e-06 DataSet_01_102
ATF3 FOXA1 siRNA Prostate LNCaP 1.5655 0.64663 - - DataSet_01_104
ATF3 HOXA1 siRNA Lung_fibroblast IMR-90 2.59204 1.37409 0.00178 0.04346 DataSet_01_110
ATF3 ID1 siRNA Lung A549 2.33955 1.22623 0.01459 0.15867 DataSet_01_117
ATF3 ZIC2 siRNA Pancreas PANC1 21.952 4.45628 - - DataSet_01_121
ATF3 EGR4 siRNA Lung SBC-5 1.53664 0.61978 0.49253 0.80041 DataSet_01_132
ATF3 ID1 shRNA Neuroepithelium GSC2 1.57816 0.65824 3.57671e-09 3.30979e-08 DataSet_01_133
ATF3 ID1 shRNA Neuroepithelium GSC8 0.52314 -0.93474 3.80081e-10 1.83111e-09 DataSet_01_134
ATF3 SPDEF shRNA Mammary_gland MCF7 1.8348 0.87562 3.99151e-05 0.00922 DataSet_01_135
ATF3 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 6.65582 2.73462 2.74931e-06 0.00087 DataSet_01_137
ATF3 IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.51299 0.5974 0.25174 0.99993 DataSet_01_138
ATF3 POLR3A siRNA Mammary_gland MCF7 2.14072 1.09809 - - DataSet_01_139
ATF3 SOX4 shRNA Parotid_gland ACC3 2.34396 1.22895 0.01868 0.92718 DataSet_01_140
ATF3 EHF siRNA Corneal_epithelial Corneal epithelial cells 0.62161 -0.68591 9.14426e-05 0.00473 DataSet_01_147
ATF3 TAL1 shRNA Umbilical_cord_blood ECFCs 2.1493 1.10387 0.00276 0.33889 DataSet_01_152
ATF3 HSF1 shRNA Skin A375 1.88003 0.91075 0.00194 0.02039 DataSet_01_155
ATF3 ELK1 siRNA Peripheral_blood CD4+ T cells 0.00864 -6.85436 0.51059 0.7178 DataSet_01_162
ATF3 GATA3 siRNA Peripheral_blood CD4+ T cells 6.04091 2.59477 0.10218 0.42789 DataSet_01_163
ATF3 JUN siRNA Peripheral_blood CD4+ T cells 0.00865 -6.85331 0.51413 0.73383 DataSet_01_164
ATF3 MAF siRNA Peripheral_blood CD4+ T cells 0.08873 -3.49437 0.9973 0.99879 DataSet_01_165
ATF3 NFATC3 siRNA Peripheral_blood CD4+ T cells 3.13671 1.64925 0.52058 0.77559 DataSet_01_166
ATF3 NFKB1 siRNA Peripheral_blood CD4+ T cells 3.28339 1.71519 0.45507 0.84261 DataSet_01_167
ATF3 STAT3 siRNA Peripheral_blood CD4+ T cells 0.00739 -7.08039 0.42615 0.99183 DataSet_01_168
ATF3 HSF1 shRNA Liver KYN2 1.55866 0.64031 - - DataSet_01_178
ATF3 TCF4 siRNA Autonomic_ganglia SH-SY5Y 2.16544 1.11466 0.00362 0.05339 DataSet_01_185
ATF3 GABPA shRNA Prostate C4-2B 1308.29 10.3535 0.23684 0.43934 DataSet_01_190
ATF3 GABPA shRNA Prostate LNCaP 906.962 9.8249 0.45945 0.7048 DataSet_01_191
ATF3 GATA2 siRNA Prostate LNCaP 3.72454 1.89706 2.18045e-05 0.00036 DataSet_01_193
ATF3 TP63 siRNA Immortalized_keratinocyte HaCaT RG 1.63658 0.71068 - - DataSet_01_196
ATF3 XBP1 shRNA Mammary_gland T47D 2.30283 1.20341 4.61738e-05 0.00085 DataSet_01_203
ATF3 MITF shRNA Skin COLO829 1.7213 0.7835 0.0997 0.27848 DataSet_01_207
ATF3 FOXM1 siRNA Mammary_gland MCF7 2.05417 1.03856 0.07348 0.6538 DataSet_01_223
ATF3 HIF1A shRNA Liver HuH7 1.61562 0.69209 - - DataSet_01_224
ATF3 IRX1 shRNA Bone_marrow 143B 1.78775 0.83814 0.03509 0.19385 DataSet_01_227
ATF3 ZEB1 siRNA Cervix HeLa229 1.80019 0.84815 - - DataSet_01_232
ATF3 FOXP1 siRNA Prostate LNCaP 0.27446 -1.86533 0.00067 0.11318 DataSet_01_234
ATF3 STAT5 shRNA Haematopoietic_and_lymphoid_tissue K562 0.45433 -1.13818 0.00067 0.00539 DataSet_01_239
ATF3 TWIST1 shRNA Stomach CAF32 1.61241 0.68922 0.0048 0.03545 DataSet_01_253
ATF3 YBX1 shRNA Mammary_gland MDA 3.73288 1.90029 1.26173e-07 3.83508e-05 DataSet_01_257
ATF3 YBX1 shRNA Mammary_gland MDA 0.65897 -0.60171 0.0538 0.24242 DataSet_01_258
ATF3 FOXO1 siRNA Umbilical_vein HUVEC 0.64843 -0.62498 8.06578e-05 0.00567 DataSet_01_270
ATF3 AHR siRNA Haematopoietic_and_lymphoid_tissue THP-1 1.59719 0.67554 2.86767e-06 0.00015 DataSet_01_283
ATF3 ZIC5 siRNA Skin A375 3.62947 1.85976 - - DataSet_01_284
ATF3 NFYA shRNA Lung H322 0.43528 -1.19997 7.07918e-05 0.0014 DataSet_01_288
ATF3 TFAP4 siRNA Brain BE(2)-C 0.15146 -2.72302 0.25436 0.51625 DataSet_01_295
ATF3 MYCN siRNA Brain BE(2)-C 2.2565 1.17409 0.72065 1 DataSet_01_296
ATF3 BRD4 siRNA Ovary Ovcar8 1.52554 0.60932 3.18901e-05 0.00106 DataSet_01_311
ATF3 TFAP2C siRNA Lung NCI-H292 1.76303 0.81805 - - DataSet_01_312
ATF3 ERG siRNA Cervix HeLa 3.25932 1.70457 4.43753e-09 5.965e-08 DataSet_01_316
ATF3 ZNF25 siRNA Bone_marrow hMSC-TERT4 0.57605 -0.79573 0.10819 0.61791 DataSet_01_319
ATF3 MYC siRNA Colon HCT116 1.79396 0.84315 0.00037 0.00134 DataSet_01_324
ATF3 TP63 shRNA Head_and_neck FaDU 0.65292 -0.61502 6.40261e-05 0.00157 DataSet_01_327
ATF3 TP63 shRNA Head_and_neck FaDU 0.65292 -0.61502 6.40261e-05 0.00157 DataSet_01_330
ATF3 TCF7L1 shRNA Colon HCT116 1.59566 0.67415 0.00074 0.01823 DataSet_01_346
ATF3 NFYA siRNA Mammary_gland MDA-MB-231 0.56022 -0.83594 - - DataSet_01_355
ATF3 PAX3 shRNA Soft_tissue Rh30 1.80629 0.85303 - - DataSet_01_359
ATF3 RBM17 shRNA Liver HepG2 0.44102 -1.18109 0.06508 0.31926 DataSet_02_100
ATF3 FIP1L1 shRNA Liver HepG2 1.88025 0.91093 0.02375 0.06761 DataSet_02_103
ATF3 HDGF shRNA Liver HepG2 2.34029 1.22668 0.00151 0.06414 DataSet_02_104
ATF3 U2AF2 shRNA Liver HepG2 4.17748 2.06263 0.03512 0.11993 DataSet_02_105
ATF3 TAF15 shRNA Liver HepG2 1.57448 0.65488 0.10331 0.15688 DataSet_02_106
ATF3 ZNF622 shRNA Liver HepG2 3.66529 1.87393 0.00087 0.00807 DataSet_02_108
ATF3 GTF2F1 shRNA Liver HepG2 1.56294 0.64426 0.00626 0.21432 DataSet_02_110
ATF3 U2AF2 shRNA Liver HepG2 2.27801 1.18777 6e-04 0.0514 DataSet_02_113
ATF3 XRCC5 shRNA Liver HepG2 1.60047 0.67849 0.03815 0.19136 DataSet_02_114
ATF3 SUB1 shRNA Liver HepG2 2.6036 1.38051 0.00049 0.12645 DataSet_02_117
ATF3 RBM25 shRNA Liver HepG2 1.99762 0.99828 0.04799 0.10275 DataSet_02_119
ATF3 EWSR1 shRNA Liver HepG2 5.57849 2.47987 0.00023 0.03947 DataSet_02_122
ATF3 PCBP2 shRNA Liver HepG2 1.50508 0.58984 0.00837 0.0725 DataSet_02_123
ATF3 HNRNPLL shRNA Liver HepG2 2.05919 1.04208 0.05136 0.09799 DataSet_02_125
ATF3 SNRNP70 shRNA Liver HepG2 5.1028 2.35129 0.00603 0.04314 DataSet_02_126
ATF3 SRSF3 shRNA Liver HepG2 3.06542 1.61609 0.01431 0.0932 DataSet_02_127
ATF3 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.57258 -0.80445 0.00657 0.03893 DataSet_02_131
ATF3 AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.23366 -2.09753 0.00046 0.08861 DataSet_02_132
ATF3 SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 1.57802 0.65811 0.0032 0.22541 DataSet_02_133
ATF3 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.52247 -0.93658 0.00102 0.02038 DataSet_02_143
ATF3 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.52513 0.60894 0.01243 0.19832 DataSet_02_144
ATF3 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.54849 0.63086 0.08131 0.35828 DataSet_02_152
ATF3 YBX3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.66513 -0.58829 0.01246 0.41577 DataSet_02_153
ATF3 SRSF4 shRNA Haematopoietic_and_lymphoid_tissue K562 1.74832 0.80597 0.18155 0.49255 DataSet_02_154
ATF3 AGO1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.51984 0.60392 0.06411 0.55254 DataSet_02_162
ATF3 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.61574 -0.6996 0.35047 0.56911 DataSet_02_163
ATF3 SSB shRNA Haematopoietic_and_lymphoid_tissue K562 2.11698 1.08201 0.00483 0.20269 DataSet_02_164
ATF3 U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.72161 0.78376 0.01517 0.14645 DataSet_02_165
ATF3 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 0.55876 -0.83969 0.02132 0.07149 DataSet_02_169
ATF3 ZFX siRNA Prostate C4-2B 2.80671 1.48888 6.45888e-05 0.00136 DataSet_02_172
ATF3 ZFX siRNA Mammary_gland MCF7 2.01941 1.01393 0.00042 0.02466 DataSet_02_206
ATF3 AR siRNA Prostate LNCaP 0.502774 -0.992017 0.186953415442603 1 DataSet_03_005
ATF3 ARID1A siRNA Oral_cavity SAS cells 1.99184 0.9941 0.0267125471551806 0.256519503384151 DataSet_03_013
ATF3 ATF3 knockout Colon HCT116 0.417399 -1.2605 0.0301551028676729 0.880950717895782 DataSet_03_017
ATF3 ATF4 siRNA Skin A375 0.499716 -1.00082 0.0839439468963549 0.775512819201899 DataSet_03_018
ATF3 CASP8AP2 siRNA Bone_marrow U2OS 1.7033 0.768329 0.000323238877745032 0.00959270165274133 DataSet_03_031
ATF3 CTNNB1 siRNA Prostate LNCaP 0.563051 -0.828661 0.398769605206576 0.925403900488465 DataSet_03_059
ATF3 EP300 siRNA Prostate LNCaP 0.392867 -1.34789 0.035536320599851 0.107165666560908 DataSet_03_065
ATF3 FOXA1 siRNA Mammary_gland MCF7 1.66939 0.73932 1.35611329482806e-06 9.0477512534532e-05 DataSet_03_080
ATF3 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 0.247356 -2.01534 - - DataSet_03_096
ATF3 GATA2 siRNA Uterus Decidual stromal cells 2.82265 1.49705 0.082661005156164 0.710327010578068 DataSet_03_100
ATF3 GATA2 siRNA Lymph Lymphatic endothelial cells 1.93051 0.948978 0.00336864178963776 0.00982295763003613 DataSet_03_101
ATF3 GATA3 siRNA Mammary_gland MCF7 2.84406 1.50795 0.0706302343792658 0.206109664414877 DataSet_03_103
ATF3 GRHL3 siRNA Skin Primary neonatal keratinocytes 0.542903 -0.881233 0.167817835443696 0.428553264812697 DataSet_03_113
ATF3 HINFP siRNA Bone_marrow U2OS 1.53612 0.61929 0.000666884641354814 0.0221250672163203 DataSet_03_123
ATF3 HMGA2 siRNA Mammary_gland MDA-MB-231 0.541626 -0.88463 0.0549783449828282 0.820203547377007 DataSet_03_125
ATF3 HNF4a siRNA Liver HepG2 1.77212 0.825476 0.13013125457075 0.747676391013422 DataSet_03_126
ATF3 HTATIP siRNA Prostate LNCaP 2.52317 1.33524 0.0127756942394531 0.0226317896419759 DataSet_03_131
ATF3 HTATIP2 siRNA Prostate LNCaP 4.16438 2.0581 0.0866441604339334 0.11583631224924 DataSet_03_132
ATF3 Klf4 siRNA Skin Primary neonatal keratinocytes 0.51946 -0.944915 0.000332553624156001 0.00457234840069727 DataSet_03_147
ATF3 KLF5 siRNA Stomach YCC3 1.54562 0.628184 0.0547268051449397 0.345848196028113 DataSet_03_151
ATF3 MEF2D shRNA Liver HuH7 8.8712 3.14913 - - DataSet_03_162
ATF3 MEF2D siRNA Liver HuH7 13.7618 3.7826 - - DataSet_03_163
ATF3 MITF siRNA Skin MZ7 1.91498 0.937332 1.75253900866709e-10 8.23883311201842e-09 DataSet_03_165
ATF3 MITF siRNA Skin Ma-Mel-15 1.67786 0.746619 0.0455302427409167 0.403569778428242 DataSet_03_166
ATF3 MYB siRNA Cord_Blood CD34+ progenitor cells 2.96035 1.56577 - - DataSet_03_170
ATF3 MYCN siRNA Brain BE(2)C cells 1.6591 0.7304 - - DataSet_03_187
ATF3 NPAT siRNA Bone_marrow U2OS 1.59219 0.671009 0.000246099594723583 0.0124749733868697 DataSet_03_201
ATF3 PHB shRNA Embryo Embryonic stem cells (ESCs) 5.1926 2.37646 1.97003203662975e-05 0.000507869568490681 DataSet_03_211
ATF3 PRRX1 CRISPR Neuroblastoma 691-MES 0.499526 -1.00137 0.130612749455174 0.89189998148014 DataSet_03_217
ATF3 RELB siRNA Immortalized_keratinocyte HaCaT 2.36403 1.24125 4.53659164781154e-06 9.87265057846384e-05 DataSet_03_227
ATF3 SMARCA4 siRNA Prostate LNCaP 0.648782 -0.624194 0.590011862298019 0.925901767600832 DataSet_03_235
ATF3 SMARCC1 siRNA Prostate LNCaP 0.652059 -0.616926 0.776440132603786 0.984741052983539 DataSet_03_236
ATF3 SOX11 siRNA Lung_fibroblast NHLF 0.663952 -0.590848 0.0464609656359107 0.320387075530967 DataSet_03_238
ATF3 SOX2 siRNA Mammary_gland GSC-11 0.558952 -0.839204 9.74107977637171e-07 0.00127700917258816 DataSet_03_245
ATF3 SP1 siRNA Ovary OVSAYO 1.80765 0.854114 0.462773515689563 0.75840598820264 DataSet_03_251
ATF3 SRF siRNA Prostate LNCaP 0.616693 -0.697376 0.1099649876041 0.346677539298198 DataSet_03_254
ATF3 SSRP1 siRNA Brain BE(2)C cells 1.67104 0.74075 0.00305191634111019 0.186251004738382 DataSet_03_255
ATF3 STAT3 CRISPR Embryo hESC 0.46529 -1.1038 0.060374320289567 0.13768560263961 DataSet_03_258
ATF3 STAT3 siRNA Prostate LNCaP 2.77694 1.4735 0.0394863435167871 0.0673659184075172 DataSet_03_262
ATF3 TET2 siRNA Prostate DU145 1.72729 0.78851 - - DataSet_03_271
ATF3 TFAP2C siRNA Mammary_gland MCF7 2.21216 1.14545 0.0186028268642141 0.30961148310492 DataSet_03_274
ATF3 TP53 knockout Haematopoietic_and_lymphoid_tissue MM1S 0.203778 -2.29493 0.141844269382777 0.994828053448528 DataSet_03_279
ATF3 TP63 siRNA Skin Primary neonatal keratinocytes 0.34489 -1.53579 0.000130054542462311 0.00331333072590747 DataSet_03_281
ATF3 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 0.193358 -2.37065 0.0210293470614091 0.0785357107616182 DataSet_04_014
ATF3 SMAD4 CRISPR Haematopoietic_and_lymphoid_tissue K562 3.32033 1.73133 0.000269553425707511 0.0979887211869635 DataSet_04_019
ATF3 ANXA2 CRISPR Liver HepG2 1.77482 0.827675 0.172334896862925 0.720180268682404 DataSet_04_024
ATF3 E4F1 CRISPR Liver HepG2 1.64821 0.720896 0.0259461702518477 0.273086496787304 DataSet_04_028
ATF3 NFX1 CRISPR Liver HepG2 5.61402 2.48903 3.56121729686032e-05 0.0107080024071796 DataSet_04_032
ATF3 SMAD5 CRISPR Liver HepG2 1.61548 0.69196 0.016667337337761 0.383089192013904 DataSet_04_036
ATF3 ZNF574 CRISPR Liver HepG2 1.82143 0.86507 0.00224937139939409 0.0567277196215169 DataSet_04_041
ATF3 ABT1 shRNA Liver HepG2 2.49307 1.31792 5.66803897809195e-05 0.00205151017163176 DataSet_04_052
ATF3 CALR shRNA Liver HepG2 1.86984 0.902913 0.000970434778194148 0.00993363935366248 DataSet_04_053
ATF3 CNOT7 shRNA Liver HepG2 0.430871 -1.21467 0.00266095143977343 0.0121318167591954 DataSet_04_051
ATF3 UBE2L3 shRNA Liver HepG2 2.2171 1.14867 0.000258871939839819 0.00716117501653716 DataSet_04_055
ATF3 NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.59102 1.37352 2.94170308333042e-05 0.0340600577442938 DataSet_04_046
ATF3 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.1312 1.09167 8.63211984791932e-05 0.00629429121468693 DataSet_02_14
ATF3 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.00495 1.00356 0.112786170705536 0.513254400420875 DataSet_02_49
ATF3 CCAR1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.516129 -0.954196 0.000410550135153083 0.0366438790055592 DataSet_04_064
ATF3 DDX1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.439915 -1.1847 0.000306634277542115 0.295295723370632 DataSet_04_063
ATF3 PRPF6 shRNA Haematopoietic_and_lymphoid_tissue K562 0.554847 -0.849837 0.252914757190775 0.625285555694921 DataSet_04_065
ATF3 ZNF830 shRNA Embryo_kidney HEK293T 1.84093 0.880434 6.382688e-04 0.0913997212 DataSet_03_315
ATF3 NFKBIZ knockout Colon Colon organoid 0.431591 -1.21226 2.220527e-02 0.613433825 DataSet_03_323
ATF3 SMARCA4 siRNA Colon HCT116 2.03318 1.02374 4.176451e-02 6.887376e-01 DataSet_03_301
ATF3 SMARCA4 siRNA Colon HCT116 1.75985 0.815451 1.397314e-02 0.1446598 DataSet_03_302
ATF3 ELF3 CRISPR Bile_duct HBDEC2 0.206926 -2.27281 1.282583e-06 1.304539e-04 DataSet_03_304
ATF3 SNAI2 shRNA Pancreas pancreatic cancer stem cells 1.90694 0.931256 2.148612e-02 0.6260175 DataSet_03_306
ATF3 LITAF siRNA Lymph KARPAS-231 0.618699 -0.692691 2.586323e-01 0.64944505 DataSet_03_309
ATF3 LITAF siRNA Lymph VAL 0.480401 -1.05769 3.286930e-01 0.744495632 DataSet_03_310
ATF3 ARID3B CRISPR Colon HCT15 1.5853 0.66476 - - DataSet_03_335
ATF3 TET1 CRISPR Mammary_gland MDA-MB-231 1.69549 0.761705 1.603108e-02 8.436215e-02 DataSet_03_347
ATF3 ZFX siRNA Prostate C4-2B 3.16735 1.66328 1.233467e-08 1.127155e-05 DataSet_03_348
ATF3 ZFX siRNA Mammary_gland MCF7 2.15148 1.10533 2.020313e-07 1.445180e-04 DataSet_03_349
ATF3 SKI CRISPR Blood HL60 1.86577 0.899769 2.120755e-02 0.264047880 DataSet_03_351
ATF3 ESR1 siRNA Mammary_gland MCF7 2.10443 1.07343 8.292190e-04 0.0174311716 DataSet_03_352
ATF3 TET1 CRISPR Mammary_gland Hs578T 2.2886 1.19447 4.103409e-04 7.282280e-03 DataSet_03_355
ATF3 CREBBP CRISPR Brain U5-NPC 2.37008 1.24494 0.1957060261 0.7490853 DataSet_03_356
ATF3 PTPN14 CRISPR Brain U5-NPC 0.641795 -0.639816 1.107557e-01 0.33380420 DataSet_03_357
ATF3 TP53 CRISPR Brain U5-NPC 3.55315 1.8291 1.662737e-02 1.623145e-01 DataSet_03_358
ATF3 RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 0.320211 -1.6429 4.823027e-03 1.052796e-01 DataSet_03_359
ATF3 MYC siRNA Peripheral_blood T lymphocyte 2.37056 1.24523 3.580410e-06 0.003293715 DataSet_03_363
ATF3 EP300 shRNA Mammary_gland MCF10AT 0.459854 -1.12075 9.256813e-03 0.071216917 DataSet_03_364
ATF3 TP53 knockout Stomach SNU1 0.649906 -0.621698 0.6948664709 0.9817357 DataSet_03_365
ATF3 ZNF148 shRNA Mammary_gland MDA-MB-231 0.589933 -0.761377 5.891785e-03 0.056164389 DataSet_03_366
ATF3 DNMT3A knockout Embryo_kidney HEK293T 54.9376 5.77972 - - DataSet_03_369
ATF3 ZFP36L1 siRNA Urinary_bladder J82 2.35294 1.23447 - - DataSet_03_371
ATF3 GLI1 siRNA Skeletal_muscle RMS13 3.4147 1.77176 2.381281e-05 0.004005592 DataSet_03_375
ATF3 ZNF213 siRNA Mammary_gland MCF7 2.13525 1.0944 1.909382e-01 6.592819e-01 DataSet_03_376
ATF3 DDX5 shRNA Stomach HGC-27 3.74717 1.9058 - - DataSet_03_379
ATF3 YY1 shRNA Brain GSC1517 1.98111 0.986312 - - DataSet_03_384
ATF3 KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 2.42659 1.27893 0.2749927723 0.8388073 DataSet_03_387
ATF3 TRIM8 siRNA Mammary_gland MCF7 4.58392 2.19658 7.441137e-04 0.0111592012 DataSet_03_388
ATF3 NFKBIA shRNA Bone_marrow U2OS 0.236135 -2.08231 8.244392e-03 0.85265333 DataSet_03_389
ATF3 ILF2 siRNA Stomach SGC-7901 2.40994 1.269 0.2332761139 0.42361759 DataSet_03_393
ATF3 ASXL1 CRISPR Embryo iPSC 0.587012 -0.768538 0.7165682617 0.9313316 DataSet_03_394
ATF3 RELA CRISPR Brain T30 1.55784 0.639549 0.4277870923 0.8400824 DataSet_03_399
ATF3 HMGA1 shRNA Bile_duct HUCCT1 2.02407 1.01726 7.373704e-02 0.313905714 DataSet_03_400
ATF3 JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 1.8101 0.856073 1.851897e-01 0.3829516 DataSet_03_403
ATF3 CDK7 shRNA Bone_marrow D458 3.82776 1.9365 4.273935e-03 0.12473510 DataSet_03_404
ATF3 TFAP2A knockout Embryo H9 1.66841 0.738472 6.522943e-03 0.05480516 DataSet_03_405
ATF3 MAP3K7 shRNA Prostate LNCaP 0.666238 -0.585891 2.703479e-03 3.697187e-02 DataSet_03_408
ATF3 USP22 shRNA Liver HuH7 6.82185 2.77016 - - DataSet_03_411
ATF3 E2F6 shRNA Liver HuH7 1.67611 0.745118 - - DataSet_03_412
ATF3 E2F2 siRNA Prostate LNCaP 1.97854 0.984434 1.180986e-05 1.019042e-03 DataSet_03_414
ATF3 RUNX2 shRNA Cord_blood Natural Killer Cell 4.31429 2.10912 6.489741e-03 0.712056201 DataSet_03_416
ATF3 FOXK2 shRNA Ovary OVCAR-5 0.489051 -1.03194 8.525686e-02 0.24901831 DataSet_03_419
ATF3 MAEL CRISPR Liver Alexander cells 0.153846 -2.70044 - - DataSet_03_423
ATF3 STAT5B CRISPR Embryo_kidney HEK293 2.52167 1.33438 9.992492e-03 0.389579771 DataSet_03_424
ATF3 FOXP3 CRISPR Peripheral_blood Naive Treg 8.62315 3.10822 1.950493e-02 0.218297706 DataSet_03_427
ATF3 USP7 shRNA Skin xenograft cells 0.454912 -1.13634 0.26252926 0.4348960 DataSet_03_431
ATF3 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 3.0227 1.59584 1.164061e-02 0.327125835 DataSet_03_434
ATF3 POU2AF1 CRISPR Lymph SUDHL4 0.153846 -2.70044 3.374873e-02 0.094295579 DataSet_03_435
ATF3 EP300 knockout Pancreas HPAF-II orthotopic cells 0.424191 -1.23721 1.139249e-05 4.086912e-04 DataSet_03_436
ATF3 SUFU shRNA Mammary_gland HCC1954 cells 1.97987 0.985406 0.0746933400 0.5891146 DataSet_03_437
ATF3 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 1.64083 0.714425 7.333976e-01 0.99496042 DataSet_03_439
ATF3 SETDB1 shRNA Colon HCT116 12.1456 3.60236 - - DataSet_03_440
ATF3 DAXX shRNA Mammary_gland MDA-MB-231 0.378532 -1.40151 1.832379e-03 0.05955500 DataSet_03_441
ATF3 HMG20A siRNA Mammary_gland MDA-MB-231 1.81465 0.859688 0.0969455050 0.3232750 DataSet_03_442
ATF3 RELB CRISPR Colon SW480 0.407942 -1.29356 6.714912e-02 2.329680e-01 DataSet_03_449
ATF3 CBX2 siRNA Mammary_gland MCF7 1.757 0.813115 9.487760e-02 0.1816059249 DataSet_03_451
ATF3 ZFP36L1 CRISPR Lung NCI-H1876 0.507828 -0.977587 4.134038e-01 0.992381486 DataSet_03_454
ATF3 SREBF2 siRNA Umbilical_vein HUVEC 0.556216 -0.846282 4.158323e-01 8.036959e-01 DataSet_03_457
ATF3 TXNIP shRNA Cord_Blood CD34+ cells 1.63087 0.705644 - - DataSet_03_461
ATF3 TXNIP shRNA Cord_blood ST3 19.75 4.30378 4.254052e-05 0.0117444063 DataSet_03_462
ATF3 PARP1 knockout Embryo_kidney HEK293a 2.01875 1.01347 4.032476e-06 4.520730e-05 DataSet_03_464
ATF3 STAT3 shRNA Liver HepG2 2.24248 1.16509 2.728508e-03 0.0676144044 DataSet_03_465
ATF3 SMARCA1 Cas13 Embryo_kidney HEK293T 7.06529 2.82075 - - DataSet_03_466
ATF3 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 4.49834 2.16939 - - DataSet_03_467
ATF3 SMARCA1 shRNA Embryo_kidney HEK293T 1.99705 0.99787 - - DataSet_03_468
ATF3 CREBBP CRISPR Lymph U2932 1.5122 0.596644 1.482748e-01 1.0000000 DataSet_03_474
Regulation Region
 
T(co)Fs that significantly regulate SOX2 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of ATF3
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines