Gene Overview
Target Gene: CHRFAM7A
NCBI Official Symbol: CHRFAM7A
Entrez ID: 89832
Ensembl ID: ENSG00000166664
Gene Full Name: CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion
Strand: -
Gene Locus: 15q13.2
External Links:

CHRFAM7A Significantly Regulated by These T(co)Fs

T(co)Fs that Activate CHRFAM7A   
T(co)Fs that Repress CHRFAM7A
The Intensity of the Gene Regulated by T(co)Fs:
CHRFAM7A-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
CHRFAM7A HOXA1 siRNA Lung_fibroblast IMR-90 2.59385 1.3751 0.10483 0.35058 DataSet_01_110
CHRFAM7A ZNF85 siRNA Gastrointestinal_tissue GIST-T1 1.57577 0.65606 0.00024 0.00506 DataSet_01_126
CHRFAM7A ELK1 siRNA Peripheral_blood CD4+ T cells 1.67833 0.74702 0.01347 0.06297 DataSet_01_162
CHRFAM7A GATA3 siRNA Peripheral_blood CD4+ T cells 1.92845 0.94744 0.00545 0.14372 DataSet_01_163
CHRFAM7A NFKB1 siRNA Peripheral_blood CD4+ T cells 1.68829 0.75556 0.01937 0.37887 DataSet_01_167
CHRFAM7A GABPA shRNA Prostate C4-2B 1905.14 10.8957 0.23842 0.43934 DataSet_01_190
CHRFAM7A GABPA shRNA Prostate LNCaP 1029.62 10.0079 0.46135 0.7048 DataSet_01_191
CHRFAM7A GATA2 siRNA Prostate LNCaP 0.50509 -0.9854 0.00015 0.00143 DataSet_01_193
CHRFAM7A HIC1 shRNA Mammary_gland HBL100 0.54576 -0.87366 - - DataSet_01_205
CHRFAM7A MYC siRNA Colon HCT116 0.60973 -0.71377 2.80365e-05 0.00015 DataSet_01_324
CHRFAM7A GATA3 siRNA Oral_cavity OEC-M1 0.58429 -0.77524 0.13859 0.99787 DataSet_01_347
CHRFAM7A GTF2B siRNA Cervix HeLa 0.60353 -0.7285 - - DataSet_01_362
CHRFAM7A RBFOX2 shRNA Liver HepG2 1.61594 0.69238 0.47135 0.77794 DataSet_02_101
CHRFAM7A FIP1L1 shRNA Liver HepG2 2.10732 1.07541 0.00866 0.03804 DataSet_02_103
CHRFAM7A TAF15 shRNA Liver HepG2 1.6338 0.70823 0.21673 0.28569 DataSet_02_106
CHRFAM7A HNRNPUL1 shRNA Liver HepG2 2.25 1.16993 0.00161 0.02246 DataSet_02_109
CHRFAM7A RBM39 shRNA Liver HepG2 1.52174 0.60572 0.39946 0.63617 DataSet_02_111
CHRFAM7A U2AF2 shRNA Liver HepG2 1.69565 0.76184 0.81252 0.87853 DataSet_02_113
CHRFAM7A PTBP1 shRNA Liver HepG2 2.65493 1.40867 0.09474 0.13022 DataSet_02_120
CHRFAM7A HNRNPLL shRNA Liver HepG2 2 1 0.01793 0.04734 DataSet_02_125
CHRFAM7A PRPF4 shRNA Liver HepG2 0.61878 -0.69249 0.24059 0.3634 DataSet_02_128
CHRFAM7A PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.36585 -1.45066 0.1333 0.22326 DataSet_02_131
CHRFAM7A AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 22 4.45943 0.09405 0.2392 DataSet_02_132
CHRFAM7A SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 2.41463 1.2718 0.64403 0.80464 DataSet_02_133
CHRFAM7A SRSF9 shRNA Haematopoietic_and_lymphoid_tissue K562 0.46341 -1.10962 0.06769 0.1798 DataSet_02_134
CHRFAM7A PCBP2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.14634 -2.77259 0.02307 0.12033 DataSet_02_135
CHRFAM7A PCBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.26829 1.18161 0.67955 0.82964 DataSet_02_137
CHRFAM7A RBM34 shRNA Haematopoietic_and_lymphoid_tissue K562 0.53659 -0.89812 0.08699 0.2919 DataSet_02_141
CHRFAM7A PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 47 5.55459 0.00419 0.19727 DataSet_02_144
CHRFAM7A CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.58824 -0.76553 0.69097 0.89446 DataSet_02_146
CHRFAM7A FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 6 2.58496 0.02515 0.11557 DataSet_02_147
CHRFAM7A ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 11.3333 3.5025 0.01759 0.26498 DataSet_02_152
CHRFAM7A SRSF4 shRNA Haematopoietic_and_lymphoid_tissue K562 0.17647 -2.5025 0.018 0.37537 DataSet_02_154
CHRFAM7A PSIP1 shRNA Haematopoietic_and_lymphoid_tissue K562 95 6.56986 0.01444 0.09011 DataSet_02_158
CHRFAM7A XRCC5 shRNA Haematopoietic_and_lymphoid_tissue K562 0.58824 -0.76553 0.12107 0.68885 DataSet_02_159
CHRFAM7A U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.17391 -2.52356 0.02792 0.17213 DataSet_02_165
CHRFAM7A RBM25 shRNA Haematopoietic_and_lymphoid_tissue K562 0.21739 -2.20163 0.0289 0.20466 DataSet_02_166
CHRFAM7A RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 0.53659 -0.89812 0.08692 0.18815 DataSet_02_168
CHRFAM7A NFE2L2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.4 -1.32193 0.12772 1 DataSet_02_174
CHRFAM7A ZNF180 siRNA Haematopoietic_and_lymphoid_tissue K562 2.43478 1.28379 0.15263 1 DataSet_02_177
CHRFAM7A TBL1XR1 siRNA Haematopoietic_and_lymphoid_tissue K562 20.5 4.35755 0.01557 1 DataSet_02_178
CHRFAM7A ATF3 siRNA Haematopoietic_and_lymphoid_tissue K562 14 3.80735 0.00718 1 DataSet_02_180
CHRFAM7A MAFK siRNA Haematopoietic_and_lymphoid_tissue K562 0.375 -1.41504 0.52046 1 DataSet_02_183
CHRFAM7A KAT2B siRNA Haematopoietic_and_lymphoid_tissue K562 0.45 -1.152 0.04652 1 DataSet_02_184
CHRFAM7A BACH1 siRNA Haematopoietic_and_lymphoid_tissue K562 6 2.58496 0.61358 1 DataSet_02_188
CHRFAM7A MAFG siRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.09448 1 DataSet_02_189
CHRFAM7A LMNB2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.33333 -1.58496 0.28434 1 DataSet_02_191
CHRFAM7A TCP1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.66667 1.41504 0.25526 1 DataSet_02_194
CHRFAM7A E2F4 siRNA Haematopoietic_and_lymphoid_tissue K562 0.33333 -1.58496 0.25161 1 DataSet_02_200
CHRFAM7A BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.08696 -3.52356 0.29551 1 DataSet_02_202
CHRFAM7A ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.09176 1 DataSet_02_203
CHRFAM7A ZFX siRNA Mammary_gland MCF7 0.02667 -5.22882 0.16191 0.3854 DataSet_02_206
CHRFAM7A HIC1 CRISPR Prostate PC3 2.38742 1.25545 - - DataSet_03_118
CHRFAM7A NR4A3 siRNA Pancreas 1.1B4 1.68398 0.75188 0.0153311794643831 0.0416107040618261 DataSet_03_203
CHRFAM7A STAT3 CRISPR Embryo hESC 2.79291 1.48177 0.0763195119788582 0.157340282750955 DataSet_03_258
CHRFAM7A YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.173077 -2.53051 0.393872902682485 0.707932159691774 DataSet_04_022
CHRFAM7A CTCF CRISPR Liver HepG2 1.52713 0.610825 0.0125150725678689 0.785672071979127 DataSet_04_027
CHRFAM7A NFX1 CRISPR Liver HepG2 0.42246 -1.24311 0.446221047672982 0.538334974854483 DataSet_04_032
CHRFAM7A SMAD4 CRISPR Liver HepG2 0.436842 -1.19482 0.0360190867089455 0.144365905959483 DataSet_04_035
CHRFAM7A SMAD5 CRISPR Liver HepG2 0.565892 -0.821403 0.179407433207154 0.576063098751165 DataSet_04_036
CHRFAM7A ACTN4 CRISPR Liver HepG2 1.71963 0.782095 0.259946929160474 0.385513732862444 DataSet_04_042
CHRFAM7A APTX CRISPR Liver HepG2 1.52713 0.610825 0.0173172438854111 0.748396033496868 DataSet_04_069
CHRFAM7A CHCHD3 CRISPR Liver HepG2 0.644068 -0.634716 0.169018412065465 0.535692638881326 DataSet_04_067
CHRFAM7A PAN2 CRISPR Liver HepG2 0.436842 -1.19482 0.0247633139538765 0.0968126484872229 DataSet_04_066
CHRFAM7A NPM1 shRNA Liver HepG2 2.00752 1.00541 0.167544026526206 0.568747179742283 DataSet_04_058
CHRFAM7A YBX3 shRNA Liver HepG2 1.89595 0.922924 0.00339971713159946 0.0533550601028606 DataSet_02_98
CHRFAM7A ACTN4 CRISPR Haematopoietic_and_lymphoid_tissue K562 2 1 0.317831306216226 0.527618796329784 DataSet_04_048
CHRFAM7A SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.238095 -2.07039 0.389072434584549 0.558835754269231 DataSet_04_049
CHRFAM7A DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.5 1.80735 0.668906714317136 0.802688057180563 DataSet_02_14
CHRFAM7A ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 30.5 4.93074 0.0523099634431845 0.135640543219701 DataSet_02_34
CHRFAM7A HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.141026 -2.82597 0.267793890582152 0.650743716654791 DataSet_02_75
CHRFAM7A HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 105 6.71425 0.128285738142485 0.618726960745477 DataSet_02_45
CHRFAM7A LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 22 4.45943 0.246091442576694 0.410445364013935 DataSet_02_35
CHRFAM7A NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 33.25 5.05528 0.459633917877561 0.6823029455417 DataSet_02_32
CHRFAM7A SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 6.5 2.70044 0.446598086815839 0.606119927711134 DataSet_02_47
CHRFAM7A SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 14 3.80735 0.0133954570474504 0.396811658374965 DataSet_02_49
CHRFAM7A TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 45 5.49185 0.0462675965204353 0.132840304514064 DataSet_02_53
CHRFAM7A ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.6 -0.736966 0.709420979985123 0.825307536603488 DataSet_04_060
CHRFAM7A CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 6.66667 2.73697 0.237955554400274 0.431221719979022 DataSet_04_061
CHRFAM7A UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.449754748976546 0.693853248769485 DataSet_04_062
CHRFAM7A SMARCA4 siRNA Colon HCT116 1.58677 0.666089 1.895170e-01 9.892536e-01 DataSet_03_301
CHRFAM7A ELF3 knockdown Bile_duct HBDEC2 0.457489 -1.12819 2.346115e-01 3.789971e-01 DataSet_03_305
CHRFAM7A SNAI2 shRNA Pancreas KLM1 0.468898 -1.09265 2.178086e-03 0.11513685 DataSet_03_307
CHRFAM7A TET1 CRISPR Mammary_gland MDA-MB-231 1.69499 0.761278 5.942928e-02 1.903736e-01 DataSet_03_347
CHRFAM7A SKI CRISPR Blood HL60 2.3 1.20163 1.645177e-02 0.237010489 DataSet_03_351
CHRFAM7A ESR1 siRNA Mammary_gland MCF7 1.6372 0.71123 1.022574e-02 0.0698628361 DataSet_03_352
CHRFAM7A TET1 CRISPR Mammary_gland Hs578T 0.335451 -1.57583 5.704326e-01 7.386724e-01 DataSet_03_355
CHRFAM7A PTPN14 CRISPR Brain U5-NPC 0.3125 -1.67807 9.091295e-02 0.31651176 DataSet_03_357
CHRFAM7A TP53 CRISPR Brain U5-NPC 0.230769 -2.11548 4.087938e-02 1.741445e-01 DataSet_03_358
CHRFAM7A ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 0.426467 -1.2295 1.600874e-01 2.460215e-01 DataSet_03_362
CHRFAM7A ZNF148 shRNA Mammary_gland MDA-MB-231 1.57132 0.651978 2.975720e-01 0.529357560 DataSet_03_366
CHRFAM7A ZFP36L1 siRNA Urinary_bladder J82 2.27273 1.18442 - - DataSet_03_371
CHRFAM7A ZNF213 siRNA Mammary_gland MCF7 2.01657 1.01191 2.655980e-01 6.592819e-01 DataSet_03_376
CHRFAM7A TCF19 CRISPR Oral_squamous CAL27 1.91493 0.937291 8.229480e-01 0.9293061786 DataSet_03_383
CHRFAM7A YY1 shRNA Brain GSC1517 0.323373 -1.62873 - - DataSet_03_384
CHRFAM7A YY1 shRNA Brain GSC23 0.331646 -1.59228 - - DataSet_03_385
CHRFAM7A YY1 shRNA Brain GSC3028 0.379366 -1.39834 - - DataSet_03_386
CHRFAM7A TRIM8 siRNA Mammary_gland MCF7 0.39255 -1.34905 4.119702e-01 0.6095715321 DataSet_03_388
CHRFAM7A NFKBIA shRNA Bone_marrow U2OS 0.103852 -3.2674 3.486271e-01 0.87005461 DataSet_03_389
CHRFAM7A IKZF2 CRISPR Lymph CAR T Cell 3.21122 1.68312 5.044248e-01 0.836665206 DataSet_03_397
CHRFAM7A EHF shRNA Stomach MKN7 0.00130676 -9.57979 - - DataSet_03_402
CHRFAM7A SATB2 CRISPR Colon Colon organoid 3 1.58496 6.793757e-01 1.00000000 DataSet_03_406
CHRFAM7A STRAP knockout Nerve SK-N-AS 6.88461 2.78338 - - DataSet_03_409
CHRFAM7A E2F1 siRNA Prostate LNCaP 0.333333 -1.58496 4.037731e-01 0.7438406902 DataSet_03_413
CHRFAM7A E2F2 siRNA Prostate LNCaP 3.33333 1.73697 1.202812e-01 3.425463e-01 DataSet_03_414
CHRFAM7A RUNX2 shRNA Cord_blood Natural Killer Cell 2.125 1.08746 5.517757e-01 0.842974826 DataSet_03_416
CHRFAM7A FOXK2 shRNA Ovary OVCAR-5 6 2.58496 1.839702e-01 0.41800359 DataSet_03_419
CHRFAM7A BRD4 CRISPR Lymph CD8+ T cells 0.5 -1 - - DataSet_03_420
CHRFAM7A PRDM1 CRISPR Lymph CD8+ T cells 5.5 2.45943 - - DataSet_03_421
CHRFAM7A USP7 shRNA Skin xenograft cells 0.391304 -1.35364 0.09190897 0.4348960 DataSet_03_431
CHRFAM7A DAXX shRNA Mammary_gland MDA-MB-231 0.129471 -2.9493 4.118123e-01 0.70091283 DataSet_03_441
CHRFAM7A CBX2 siRNA Mammary_gland MCF7 1.69423 0.760631 5.120243e-01 0.6766764204 DataSet_03_451
CHRFAM7A OGT siRNA Embryo BeWo cells 5 2.32193 2.623142e-01 0.66237450 DataSet_03_453
CHRFAM7A ARID1A shRNA Bile_duct MMNK1 0.323698 -1.62728 2.483142e-01 0.545953811 DataSet_03_458
CHRFAM7A STAT3 shRNA Liver HepG2 1.81818 0.862496 5.574629e-01 0.7655004791 DataSet_03_465
CHRFAM7A WHSC1 siRNA Prostate PC3 1.52778 0.611435 3.731652e-01 0.58815838 DataSet_03_471
Regulation Region
 
T(co)Fs that significantly regulate ERF by the evidences of both expression and ChIP-seq/motif
Expression Atlas of CHRFAM7A
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines