Gene Overview
| Target Gene: | Eif2s3y |
| NCBI Official Symbol: | Eif2s3y |
| Entrez ID: | 26908 |
| Ensembl ID: | ENSMUSG00000069049 |
| Gene Full Name: | eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked |
| Strand: | + |
| Gene Locus: | Y|Ypter |
| External Links: |
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Eif2s3y Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Eif2s3y
T(co)Fs
that Repress Eif2s3y
The Intensity of the Gene Regulated by T(co)Fs:
Eif2s3y-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Eif2s3y | Adnp | knockout | Embryo | Whole embryonic body | 91.1818 | 6.51067 | 0.000850718959129 | 0.188950122566078 | DataSet_11_001 |
| Eif2s3y | Arid1a | knockout | Liver | Liver | 0.460295 | -1.11937 | 0.558758506660554 | 0.999999999999956 | DataSet_11_004 |
| Eif2s3y | Atf4 | knockout | Brain | Embryonic neurons | 1.62981 | 0.704708 | 0.163875550284391 | 0.566211624083938 | DataSet_11_008 |
| Eif2s3y | Atoh1 | knockout | Gastrointestinal_tissue | Intestinal epithelial Lgr5(hi) stem cells | 0.0428045 | -4.54609 | 0.296558005360098 | 0.410650285152801 | DataSet_11_010 |
| Eif2s3y | Bcl6 | knockout | Bone_marrow | Myeloid cells | 61.6955 | 5.94709 | 4.02946693483278e-15 | 4.17875868476834e-11 | DataSet_11_015 |
| Eif2s3y | Bhlha9 | knockout | Limb | Whole limb bud | 0.341626 | -1.54951 | - | - | DataSet_11_016 |
| Eif2s3y | Cebpb | knockout | Bone_marrow | Bone marrow-derived macrophages | 3.93629 | 1.97684 | - | - | DataSet_11_021 |
| Eif2s3y | E2f4 | knockout | Brain | Forebrain | 3.07921 | 1.62256 | - | - | DataSet_11_033 |
| Eif2s3y | E2f4 | knockout | Brain | Forebrain | 4.00459 | 2.00166 | - | - | DataSet_11_034 |
| Eif2s3y | Gata5 | knockout | Lung | Left lung | 1.88176 | 0.912083 | 0.2066214397716 | 0.366661129560468 | DataSet_11_051 |
| Eif2s3y | Gfi1 | knockout | Cord_Blood | T-cells | 11.4933 | 3.52272 | 0.014047174644872 | 0.260793201063557 | DataSet_11_053 |
| Eif2s3y | Grhl2 | knockout | Embryo | V6.5 | 0.574987 | -0.7984 | 0.12675264062346 | 0.404224089918733 | DataSet_11_055 |
| Eif2s3y | Irf6 | knockout | Skin | Skin | 2.82969 | 1.50064 | 0.0685982821555926 | 0.323583572933624 | DataSet_11_062 |
| Eif2s3y | Jarid2 | knockout | Pancreas | Embryonic pancreas | 0.0457456 | -4.45022 | 0.0839875814216024 | 0.768712461908223 | DataSet_11_064 |
| Eif2s3y | Lhx8 | knockout | Ovary | Ovary | 0.645977 | -0.630445 | 0.330870946083992 | 0.496857391596298 | DataSet_11_070 |
| Eif2s3y | Lmx1b | knockout | Limb | Proximal limb | 0.531955 | -0.910625 | 0.0896359085318589 | 0.560296845697368 | DataSet_11_071 |
| Eif2s3y | Lmx1b | knockout | Kidney | Kidney | 1.98056 | 0.985908 | 0.287438424433941 | 0.620126373387796 | DataSet_11_072 |
| Eif2s3y | Mafg | knockout | Embryo | Whole embryo | 2.09726 | 1.0685 | 6.58190888504982e-12 | 1.42221887188156e-08 | DataSet_11_073 |
| Eif2s3y | Mbd1 | siRNA | Adipose_tissue | 3T3-L1 cells | 3 | 1.58496 | - | - | DataSet_11_074 |
| Eif2s3y | Mbd2 | knockout | Lymph | GFP+ BM leukemia cells | 38.0709 | 5.25062 | 4.06752525826006e-11 | 1.20520773402245e-07 | DataSet_11_076 |
| Eif2s3y | Myb | shRNA | Hematopoietic | AML cells | 1.76117 | 0.816533 | 0.26914784834993 | 0.539061084348665 | DataSet_11_084 |
| Eif2s3y | Neurod1 | knockout | Eye | Pineal gland | 1.78776 | 0.838153 | 0.542047644428095 | 0.9983937273602 | DataSet_11_089 |
| Eif2s3y | Nhlh2 | knockout | Eye | Retina | 0.463694 | -1.10875 | 0.151704245076761 | 0.523726874680013 | DataSet_11_092 |
| Eif2s3y | Nr2f2 | knockout | Ovary | E14.5 Ovary | 0.544242 | -0.877679 | 0.716648873883281 | 0.958114863542569 | DataSet_11_094 |
| Eif2s3y | Otx2 | knockout | Eye | Retina | 0.474018 | -1.07699 | 0.15588431956382 | 0.999923528647439 | DataSet_11_097 |
| Eif2s3y | Pax5 | knockout | Bone_marrow | B220+ cells | 0.158174 | -2.66041 | 0.105819911431211 | 0.50201527515891 | DataSet_11_100 |
| Eif2s3y | Pitx2 | knockout | Eye | Cornea | 5.38071 | 2.4278 | 0.301338148651799 | 0.680110606452178 | DataSet_11_103 |
| Eif2s3y | Plagl2 | knockout | Intestine | Small intestine | 0.450451 | -1.15056 | 0.0837776569379737 | 0.340813030058187 | DataSet_11_104 |
| Eif2s3y | Pparg | siRNA | Adipose_tissue | Preadipocytes | 1.57927 | 0.659257 | 0.847376334569102 | 0.999962577291099 | DataSet_11_105 |
| Eif2s3y | Prdm1 | knockout | Intestine | Mid-intestine | 3.17724 | 1.66778 | 0.00648127879891319 | 0.00903112671764895 | DataSet_11_106 |
| Eif2s3y | Prdm14 | knockout | Embryo | ES cells | 3.21107 | 1.68306 | 1.76390026448632e-10 | 1.66494545964863e-07 | DataSet_11_107 |
| Eif2s3y | Prox1 | knockout | Liver | Liver | 703.28 | 9.45796 | - | - | DataSet_11_109 |
| Eif2s3y | Rest | shRNA | Brain | NSP | 0.646582 | -0.629095 | 0.199526470485479 | 0.999899167758865 | DataSet_11_111 |
| Eif2s3y | Rest | knockout | Brain | Brain | 2.06495 | 1.04611 | 0.0639349081590081 | 1 | DataSet_11_113 |
| Eif2s3y | Runx1 | knockout | Lymph | ProB cells | 1.87511 | 0.906972 | 0.124923932849042 | 0.409967086129982 | DataSet_11_116 |
| Eif2s3y | Sall4 | shRNA | Embryo | ES cells | 0.430387 | -1.21629 | 0.210809577321673 | 0.999840995136314 | DataSet_11_123 |
| Eif2s3y | Shox2 | knockout | Muscle | Embryonic forelimb | 19.5429 | 4.28857 | 1.88057521047704e-07 | 0.0037603981908699 | DataSet_11_125 |
| Eif2s3y | Smad1 | knockout | Lung | Lung left lobe | 0.534448 | -0.903878 | 0.0982614984342412 | 0.542998753027287 | DataSet_11_126 |
| Eif2s3y | Smad4 | siRNA | Brain | bEnd3 | 0.0125036 | -6.32151 | - | - | DataSet_11_127 |
| Eif2s3y | Sox11 | knockout | Eye | Retina | 0.0224373 | -5.47796 | - | - | DataSet_11_137 |
| Eif2s3y | Sox11 | knockout | Brain | Cortex | 66.346 | 6.05194 | - | - | DataSet_11_138 |
| Eif2s3y | Sox9 | knockout | Lung | Trachea | 3.20673 | 1.6811 | 0.207305687421396 | 0.565890186212066 | DataSet_11_144 |
| Eif2s3y | Spdef | knockout | Colon | Colon | 0.205215 | -2.2848 | 0.0668604381347486 | 0.997507742354799 | DataSet_11_146 |
| Eif2s3y | Stat4 | knockout | Lymph | Lamina propria lymphocytes | 0.485799 | -1.04157 | 0.135465977526783 | 0.917862474892292 | DataSet_11_152 |
| Eif2s3y | Tbx1 | knockout | Ear | Otic vesicles | 1.73765 | 0.797133 | 0.261818509450237 | 0.996209135879357 | DataSet_11_154 |
| Eif2s3y | Tet2 | shRNA | Embryo | ES cells | 8.76638 | 3.13198 | - | - | DataSet_11_161 |
| Eif2s3y | Thap11 | knockout | Heart | Heart | 1.86388 | 0.898308 | 0.167589388744547 | 0.999994817864919 | DataSet_11_167 |
| Eif2s3y | Vax2 | knockout | Eye | Whole eye | 1.94727 | 0.961454 | 0.387077109018617 | 0.999998533525589 | DataSet_11_173 |
| Eif2s3y | Wt1 | knockout | Oviduct | Oviduct | 0.517161 | -0.951316 | 0.00184811007973873 | 0.474840029056187 | DataSet_11_180 |
| Eif2s3y | Cpeb1 | siRNA | Neuron | Neuro-2a | 2.55855 | 1.35533 | - | - | DataSet_11_189 |
| Eif2s3y | Mapk9 | knockout | Hip | Mouse Hip Cartilage | 2.10276 | 1.07228 | 5.645507e-03 | 1.794113e-02 | DataSet_11_236 |
| Eif2s3y | Tet1 | knockout | Embryo | ES cells | 0.0344785 | -4.85816 | 7.032597e-06 | 0.05065345 | DataSet_11_216 |
| Eif2s3y | Dnmt1 | knockout | Embryo | Embryonic fibroblasts | 24.8 | 4.63227 | 1.329440e-05 | 9.478977e-04 | DataSet_11_192 |
| Eif2s3y | Ezh2 | knockout | Bone_marrow | CD45.2+LSK cells | 96.2182 | 6.58824 | - | - | DataSet_11_220 |
| Eif2s3y | Bcl11b | knockdown | Embryo | Embryonic fibroblasts | 1.54195 | 0.624753 | - | - | DataSet_11_226 |
| Eif2s3y | Crebbp | knockout | Spleen | Germinal center B cells | 3.10455 | 1.63438 | 2.351140e-01 | 0.863453764 | DataSet_11_227 |
| Eif2s3y | Bcl11b | knockout | Main_olfactory_epithelium | main olfactory epithelium (MOE) | 0.578029 | -0.790786 | - | - | DataSet_11_207 |
| Eif2s3y | Dnmt3a | siRNA | Embryo | iPSC | 26.8915 | 4.74908 | - | - | DataSet_11_241 |
| Eif2s3y | Dnmt3b | siRNA | Embryo | iPSC | 2.17869 | 1.12346 | - | - | DataSet_11_242 |
| Eif2s3y | Ezh2 | knockout | Calvaria | calvaria | 0.00863214 | -6.85607 | 2.915375e-01 | 0.57103262 | DataSet_11_247 |
| Eif2s3y | Kmt2d | knockout | Skin | iBiP melanoma mouse model tumor cell | 0.00783949 | -6.99503 | 5.515447e-08 | 3.269004e-05 | DataSet_11_250 |
| Eif2s3y | Eed | knockout | Brain | Forebrain | 2.05344 | 1.03804 | 1.330671e-02 | 3.075291e-01 | DataSet_11_258 |
| Eif2s3y | Eed | knockout | Brain | hindbrain | 2.05834 | 1.04148 | 1.212369e-02 | 4.345239e-01 | DataSet_11_259 |
| Eif2s3y | Eed | knockout | Brain | midbrain | 1.86631 | 0.90019 | 1.381136e-02 | 4.063202e-01 | DataSet_11_260 |
| Eif2s3y | Eed | knockout | Spinal_cord | spinal cord | 2.04902 | 1.03493 | 1.282327e-02 | 9.999790e-01 | DataSet_11_261 |
| Eif2s3y | Dux | knockout | Embryo | Embryo | 0.43014 | -1.21712 | 3.062287e-01 | 4.923379e-01 | DataSet_11_269 |
| Eif2s3y | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 1.99447 | 0.996007 | 7.079660e-01 | 0.95217294 | DataSet_11_272 |
| Eif2s3y | Dux | knockout | Embryo | Embryo | 0.43014 | -1.21712 | 3.062285e-01 | 4.923669e-01 | DataSet_11_273 |
| Eif2s3y | Lin28b | knockout | Bone_marrow | Bone marrow immature B cells | 0.455837 | -1.13341 | 4.056691e-01 | 0.9643594 | DataSet_11_274 |
| Eif2s3y | Gsk3b | CRISPR | Neuron | mPFC D2 neurons | 1.80773 | 0.854182 | 1.929912e-01 | 0.85266614 | DataSet_11_277 |
| Eif2s3y | Setd2 | knockout | Kidney | primary renal tubular epithelial (RTE) cells | 0.318465 | -1.65079 | - | - | DataSet_11_285 |
| Eif2s3y | Med19 | knockout | White_adipose_tissue | Gonadal white adipose tissue | 0.520618 | -0.941702 | 8.523722e-01 | 9.560523e-01 | DataSet_11_289 |
| Eif2s3y | Irf8 | knockout | Brain | mice brain | 0.161418 | -2.63113 | 3.199406e-03 | 3.845580e-01 | DataSet_11_292 |
| Eif2s3y | Setd1a | shRNA | Eye | Retina | 0.0246154 | -5.34429 | 1.973612e-02 | 0.1021492779 | DataSet_11_293 |
| Eif2s3y | Tfap2a | knockout | Brain | Brain | 1.72137 | 0.783558 | 0.0469716310 | 0.9599640 | DataSet_11_295 |
| Eif2s3y | Phf8 | knockout | prostate | Prostate | 0.637812 | -0.648796 | 0.3190970348 | 0.5658847 | DataSet_11_298 |
| Eif2s3y | Arid2 | knockout | Muscle | LSK | 0.01159 | -6.43097 | 3.118354e-13 | 6.918934e-10 | DataSet_11_301 |
| Eif2s3y | Esr1 | knockout | Liver | Liver | 1.53898 | 0.621972 | 3.603610e-01 | 1.0000000 | DataSet_11_307 |
| Eif2s3y | Suz12 | knockout | Lung | Alveolar macrophage | 2.72738 | 1.44751 | 1.344291e-01 | 2.097854e-01 | DataSet_11_312 |
| Eif2s3y | Irf7 | knockout | Bone_marrow | c-kit+ leukemic cells | 0.571429 | -0.807355 | - | - | DataSet_11_313 |
| Eif2s3y | Satb2 | knockout | Colon | Intestine epithelium | 0.49422 | -1.01678 | 6.499231e-01 | 0.8163210929 | DataSet_11_316 |
| Eif2s3y | Gata2 | knockout | Brain | Pituitary gland | 1.56291 | 0.644234 | 0.415094230 | 1.0000000 | DataSet_11_322 |
| Eif2s3y | Ezh2 | shRNA | Brain | SVZ derived neural stem cells | 4.20329 | 2.07152 | 6.953171e-02 | 2.842265e-01 | DataSet_11_332 |
| Eif2s3y | Ezh2 | knockout | Eye | Retina | 1.74978 | 0.807171 | 3.454672e-02 | 2.836561e-01 | DataSet_11_333 |
| Eif2s3y | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 0.663113 | -0.592673 | 6.215844e-02 | 0.125971385 | DataSet_11_340 |
| Eif2s3y | Dnmt1 | knockout | Kidney | kidney Cap Mesenchyme | 0.264125 | -1.92071 | 2.733285e-01 | 5.641605e-01 | DataSet_11_344 |
Regulation Region
Expression Atlas of Eif2s3y