Gene Overview
Target Gene: FAM81A
NCBI Official Symbol: FAM81A
Entrez ID: 145773
Ensembl ID: ENSG00000157470
Gene Full Name: family with sequence similarity 81 member A
Strand: +
Gene Locus: 15q22.2
External Links:

FAM81A Significantly Regulated by These T(co)Fs

T(co)Fs that Activate FAM81A   
T(co)Fs that Repress FAM81A
The Intensity of the Gene Regulated by T(co)Fs:
FAM81A-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
FAM81A ESRRA shRNA Colon HCT116 0.66023 -0.59897 0.03508 0.84512 DataSet_01_115
FAM81A ID1 siRNA Lung A549 0.36269 -1.4632 0.05457 0.24803 DataSet_01_117
FAM81A ZIC2 siRNA Pancreas PANC1 4.44279 2.15147 - - DataSet_01_121
FAM81A FOXM1 siRNA Central_nervous_system U87 1.62979 0.70468 - - DataSet_01_122
FAM81A IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 0.40052 -1.32004 0.03292 0.55937 DataSet_01_137
FAM81A POLR3A siRNA Mammary_gland MCF7 1.99689 0.99776 - - DataSet_01_139
FAM81A LIN28B siRNA Embryo_kidney HEK293 0.49827 -1.00501 0.00021 0.01151 DataSet_01_153
FAM81A HSF1 shRNA Skin A375 1.54698 0.62945 0.00021 0.0039 DataSet_01_155
FAM81A ELK1 siRNA Peripheral_blood CD4+ T cells 0.55408 -0.85184 0.95953 0.9811 DataSet_01_162
FAM81A GATA3 siRNA Peripheral_blood CD4+ T cells 0.48359 -1.04815 0.92826 0.96832 DataSet_01_163
FAM81A JUN siRNA Peripheral_blood CD4+ T cells 0.36385 -1.45857 0.65014 0.82013 DataSet_01_164
FAM81A MAF siRNA Peripheral_blood CD4+ T cells 0.38957 -1.36004 0.74215 0.89251 DataSet_01_165
FAM81A NFATC3 siRNA Peripheral_blood CD4+ T cells 0.47888 -1.06226 0.96835 0.98571 DataSet_01_166
FAM81A NFKB1 siRNA Peripheral_blood CD4+ T cells 0.50556 -0.98404 0.9802 0.99398 DataSet_01_167
FAM81A STAT3 siRNA Peripheral_blood CD4+ T cells 0.30771 -1.70035 0.46189 0.99183 DataSet_01_168
FAM81A HSF1 shRNA Liver KYN2 0.33747 -1.56717 - - DataSet_01_178
FAM81A GATA2 siRNA Prostate LNCaP 0.20602 -2.27914 1.34995e-05 0.00025 DataSet_01_193
FAM81A CREB1 shRNA Parotid_gland H3118 MEC 3.11526 1.63935 0.56305 0.82431 DataSet_01_194
FAM81A MITF shRNA Skin COLO829 0.56085 -0.83431 0.00028 0.01036 DataSet_01_207
FAM81A LIN28A siRNA Embryo H9 0.45814 -1.12615 0.00614 0.03702 DataSet_01_215
FAM81A ERG siRNA Prostate VCaP 0.47024 -1.08853 0.00173 0.03013 DataSet_01_216
FAM81A TWIST1 shRNA Stomach CAF32 0.51868 -0.94709 0.00814 0.04621 DataSet_01_253
FAM81A SOX4 shRNA Mammary_gland MDA-MB-231 1.50333 0.58816 0.0059 0.09345 DataSet_01_260
FAM81A IRF4 shRNA Lymph BL2 0.63869 -0.6468 - - DataSet_01_262
FAM81A SNAI2 siRNA Mammary_gland MCFDCIS 0.22046 -2.18139 0.00025 0.3653 DataSet_01_292
FAM81A TFAP4 siRNA Brain BE(2)-C 0.17241 -2.53609 0.30958 0.51625 DataSet_01_295
FAM81A PTEN shRNA Skin A431 0.56935 -0.81261 0.00286 0.07081 DataSet_01_301
FAM81A PTEN shRNA Mammary_gland SKBR3 3.13125 1.64674 0.10186 0.61045 DataSet_01_303
FAM81A OVOL2 siRNA Corneal_epithelial Corneal epithelial cells 0.35011 -1.51413 0.16664 0.38776 DataSet_01_313
FAM81A MYC siRNA Colon HCT116 0.30454 -1.71531 0.00019 0.00075 DataSet_01_324
FAM81A GATA3 siRNA Oral_cavity OEC-M1 1.71213 0.77579 0.20409 0.99787 DataSet_01_347
FAM81A HIF1A siRNA Oral_cavity OEC-M1 1.70686 0.77134 0.22117 0.85151 DataSet_01_348
FAM81A ELK1 siRNA Mammary_gland MDA-MB-231 1.53904 0.62203 - - DataSet_01_354
FAM81A ETV4 shRNA Prostate PC3 0.52924 -0.91801 - - DataSet_01_356
FAM81A PAX3 shRNA Soft_tissue Rh30 0.54433 -0.87745 - - DataSet_01_359
FAM81A RBM17 shRNA Liver HepG2 3.88889 1.95936 0.82777 0.92248 DataSet_02_100
FAM81A FIP1L1 shRNA Liver HepG2 8.83333 3.14296 0.03421 0.08492 DataSet_02_103
FAM81A HDGF shRNA Liver HepG2 0.38298 -1.38466 0.6002 0.73988 DataSet_02_104
FAM81A SSB shRNA Liver HepG2 0.21429 -2.22239 0.14271 0.20073 DataSet_02_107
FAM81A HNRNPUL1 shRNA Liver HepG2 1.63265 0.70722 0.48137 0.57057 DataSet_02_109
FAM81A GTF2F1 shRNA Liver HepG2 3.22222 1.68806 0.51821 0.7757 DataSet_02_110
FAM81A RBM39 shRNA Liver HepG2 5.88889 2.558 0.01186 0.21151 DataSet_02_111
FAM81A TARDBP shRNA Liver HepG2 0.25275 -1.98423 0.02257 0.06024 DataSet_02_116
FAM81A SUB1 shRNA Liver HepG2 0.44444 -1.16993 0.06335 0.21802 DataSet_02_117
FAM81A CEBPZ shRNA Liver HepG2 4 2 0.1431 1 DataSet_02_118
FAM81A EWSR1 shRNA Liver HepG2 1.55319 0.63524 0.36284 0.49 DataSet_02_122
FAM81A HNRNPLL shRNA Liver HepG2 0.35165 -1.50779 0.08768 0.14507 DataSet_02_125
FAM81A SNRNP70 shRNA Liver HepG2 0.41758 -1.25987 0.05723 0.13228 DataSet_02_126
FAM81A PRPF4 shRNA Liver HepG2 0.01639 -5.93074 0.04387 0.1176 DataSet_02_128
FAM81A ESR1 siRNA Mammary_gland MCF7 0.661408 -0.596388 0.0261383778750931 0.047492340191715 DataSet_03_071
FAM81A GATA2 siRNA Uterus Decidual stromal cells 0.484158 -1.04645 0.0157139630242091 0.470658187122058 DataSet_03_100
FAM81A HIC1 CRISPR Prostate PC3 1.64921 0.721772 - - DataSet_03_118
FAM81A HINFP siRNA Bone_marrow U2OS 0.56707 -0.818401 0.000207885554566434 0.0144229911295473 DataSet_03_123
FAM81A HNF4a siRNA Liver HepG2 1.93169 0.949867 0.0191848611432842 0.545206130397354 DataSet_03_126
FAM81A MEF2D siRNA Liver HuH7 0.570833 -0.80886 - - DataSet_03_163
FAM81A MITF siRNA Skin MZ7 0.267115 -1.90447 7.20966444321621e-09 2.06209479136804e-07 DataSet_03_165
FAM81A MITF siRNA Skin Ma-Mel-15 0.385396 -1.37559 0.0013457998826268 0.063081641525396 DataSet_03_166
FAM81A MITF siRNA Skin Ma-Mel-15 0.420302 -1.2505 2.32191228302581e-05 0.00195006899392332 DataSet_03_167
FAM81A MITF siRNA Skin SK-MEL-5 0.449471 -1.1537 6.12591412380259e-07 1.05666469800338e-05 DataSet_03_168
FAM81A MYC siRNA Central_nervous_system DAOY M2.1 0.406236 -1.29961 4.31526641774475e-08 9.34792552355631e-07 DataSet_03_178
FAM81A NR2F2 siRNA Uterus Primary eutopic stromal cells 1.67783 0.746595 0.152962212439517 0.99947668859931 DataSet_03_202
FAM81A SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 1.64706 0.719892 - - DataSet_03_246
FAM81A SP1 siRNA Cervix HeLa 1.59774 0.676035 0.000136011732992024 0.00226216135018608 DataSet_03_249
FAM81A STAT3 CRISPR Embryo hESC 1.71335 0.77682 0.145174754206577 0.210921766046208 DataSet_03_258
FAM81A STAT6 siRNA Umbilical_vein HUVEC 1.74194 0.800691 0.649755492929364 0.950989632445664 DataSet_03_264
FAM81A TFE3 siRNA Kidney UOK257-2 0.515594 -0.955692 - - DataSet_03_275
FAM81A TP53 siRNA Foreskin Neonatal foreskin keratinocytes 0.558424 -0.840567 0.0533538588181244 0.999791649573014 DataSet_03_278
FAM81A TP63 siRNA Foreskin Neonatal foreskin keratinocytes 0.52595 -0.927003 0.0422639933106271 0.729684006943091 DataSet_03_282
FAM81A E4F1 CRISPR Liver HepG2 0.337838 -1.5656 0.0575875786516925 0.317724222425685 DataSet_04_028
FAM81A ERN1 CRISPR Liver HepG2 3.06667 1.61667 0.0826127596834282 0.243718986575049 DataSet_04_029
FAM81A PAN2 CRISPR Liver HepG2 1.72727 0.788496 0.175720535164699 0.349717574527985 DataSet_04_033
FAM81A SMAD4 CRISPR Liver HepG2 2.16667 1.11548 0.11836963722987 0.260513973786692 DataSet_04_035
FAM81A ZC3H8 shRNA Liver HepG2 0.478261 -1.06413 0.00752711011882375 0.0950485526774727 DataSet_04_040
FAM81A ZNF574 CRISPR Liver HepG2 0.227273 -2.1375 0.0733584316098497 0.176891580104339 DataSet_04_041
FAM81A ACTN4 CRISPR Liver HepG2 0.5 -1 0.0333908042277494 0.102230550421271 DataSet_04_042
FAM81A APTX CRISPR Liver HepG2 0.243243 -2.03953 0.174228720849721 0.798663943920142 DataSet_04_069
FAM81A PAN2 CRISPR Liver HepG2 2.16667 1.11548 0.122077152675225 0.260704868767253 DataSet_04_066
FAM81A ABT1 shRNA Liver HepG2 0.0521739 -4.26053 0.000679698198213587 0.00669465057658316 DataSet_04_052
FAM81A CALR shRNA Liver HepG2 0.491525 -1.02466 0.183866021690153 0.303024056959398 DataSet_04_053
FAM81A CCAR1 shRNA Liver HepG2 3.21739 1.68589 0.0166656425616969 0.0645746563578826 DataSet_04_054
FAM81A DDX1 shRNA Liver HepG2 0.489796 -1.02975 0.267254801705585 0.510426567462732 DataSet_04_057
FAM81A NPM1 shRNA Liver HepG2 2.77778 1.47393 0.383056308094882 0.782495951272286 DataSet_04_058
FAM81A PRPF6 shRNA Liver HepG2 4.80556 2.2647 0.0135070554275067 0.0872439890891813 DataSet_04_056
FAM81A SMARCA4 siRNA Colon HCT116 0.567927 -0.816221 1.175779e-01 9.892536e-01 DataSet_03_301
FAM81A SNAI2 shRNA Pancreas KLM1 0.643251 -0.636546 1.430242e-01 0.49550621 DataSet_03_307
FAM81A TET1 CRISPR Mammary_gland MDA-MB-231 2.01672 1.01201 4.788565e-02 1.661151e-01 DataSet_03_347
FAM81A SKI CRISPR Blood HL60 0.322691 -1.63178 1.640432e-03 0.090982843 DataSet_03_351
FAM81A PTPN14 CRISPR Brain U5-NPC 0.186747 -2.42084 1.188786e-03 0.15389182 DataSet_03_357
FAM81A TP53 CRISPR Brain U5-NPC 2.69231 1.42884 1.489455e-02 1.623145e-01 DataSet_03_358
FAM81A TP53 knockout Stomach SNU1 1.5978 0.676086 0.1684782862 0.9301241 DataSet_03_365
FAM81A USP22 shRNA Liver PLC_PRF_5 cells 1.57951 0.659473 7.689459e-02 0.26348655 DataSet_03_368
FAM81A E2F1 siRNA Nasopharynx HK1 0.0733431 -3.7692 2.510671e-05 1.600390e-03 DataSet_03_373
FAM81A GLI1 siRNA Skeletal_muscle RMS13 1.55263 0.634711 2.225438e-02 0.119902818 DataSet_03_375
FAM81A DDX5 shRNA Stomach HGC-27 0.183575 -2.44556 - - DataSet_03_379
FAM81A DNMT1 siRNA Skin Human melanoma cells 0.646845 -0.628508 5.361768e-05 3.379268e-04 DataSet_03_382
FAM81A TCF19 CRISPR Oral_squamous CAL27 1.5829 0.662569 1.471329e-02 0.0966840773 DataSet_03_383
FAM81A KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 0.547608 -0.868784 0.0963531577 0.8388073 DataSet_03_387
FAM81A NFKBIA shRNA Bone_marrow U2OS 0.319293 -1.64705 5.842680e-01 0.87005461 DataSet_03_389
FAM81A YY1 knockdown Liver HepG2 0.583333 -0.777608 5.169701e-01 6.423034e-01 DataSet_03_390
FAM81A ILF2 siRNA Stomach SGC-7901 2.55051 1.35078 0.1351429465 0.30362292 DataSet_03_393
FAM81A RELA CRISPR Brain T30 0.421646 -1.2459 0.2947865466 0.8400824 DataSet_03_399
FAM81A EHF shRNA Stomach MKN7 0.0315196 -4.98761 - - DataSet_03_402
FAM81A CDK7 shRNA Bone_marrow D458 1.5422 0.624993 3.256178e-01 0.61666263 DataSet_03_404
FAM81A TFAP2A knockout Embryo H9 3.33333 1.73697 2.000844e-02 0.08965573 DataSet_03_405
FAM81A CHD1 shRNA Prostate LNCaP 0.57859 -0.789388 1.022377e-02 2.309649e-01 DataSet_03_407
FAM81A SIRT1 siRNA Pancreas PANC1 2.07634 1.05404 1.580135e-02 0.065499110 DataSet_03_410
FAM81A E2F6 shRNA Liver HuH7 0.425838 -1.23162 - - DataSet_03_412
FAM81A FOXK2 shRNA Ovary OVCAR-5 2.8306 1.50111 1.403147e-02 0.10345472 DataSet_03_419
FAM81A MAEL CRISPR Liver Alexander cells 1.61539 0.691878 - - DataSet_03_423
FAM81A FOXP3 CRISPR Peripheral_blood Naive Treg 2.72727 1.44746 3.026164e-02 0.257546329 DataSet_03_427
FAM81A IKZF2 shRNA Lymph Hut78 0.466063 -1.1014 1.173033e-02 0.40530138 DataSet_03_429
FAM81A STAT3 siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 0.518182 -0.94847 0.0597488391 1 DataSet_03_430
FAM81A USP7 shRNA Skin xenograft cells 0.306198 -1.70746 0.26025721 0.4348960 DataSet_03_431
FAM81A PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.608696 -0.716207 - - DataSet_03_432
FAM81A FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 2.66667 1.41504 4.685379e-02 0.81654770 DataSet_03_439
FAM81A SETDB1 shRNA Colon HCT116 0.197334 -2.34129 - - DataSet_03_440
FAM81A DAXX shRNA Mammary_gland MDA-MB-231 0.375417 -1.41343 5.019805e-01 0.76179052 DataSet_03_441
FAM81A HMG20A siRNA Mammary_gland MDA-MB-231 2.2 1.1375 0.0739721252 0.2852319 DataSet_03_442
FAM81A PHF14 siRNA Mammary_gland MDA-MB-231 1.90435 0.929297 0.0334711875 0.3838319 DataSet_03_443
FAM81A PURA siRNA Cervix HeLa 2.00936 1.00674 5.912167e-04 0.039078791 DataSet_03_444
FAM81A CAMTA1 knockout Embryo_kidney HEK293T 1.5037 0.58852 3.267862e-02 0.15721588 DataSet_03_448
FAM81A CBX2 siRNA Mammary_gland MDA-MB-231 0.546953 -0.87051 4.108311e-03 2.458733e-02 DataSet_03_450
FAM81A SMARCA2 shRNA Lung HCC2302 1.93205 0.950133 2.831221e-04 4.755394e-04 DataSet_03_455
FAM81A PPARG siRNA Aortic_valve Valvular endothelial cell 0.484848 -1.04439 2.504828e-01 7.130359e-01 DataSet_03_456
FAM81A SREBF2 siRNA Umbilical_vein HUVEC 1.80931 0.855443 6.554994e-02 4.100301e-01 DataSet_03_457
FAM81A ARID1A shRNA Bile_duct MMNK1 3.05173 1.60962 3.859087e-04 0.018895236 DataSet_03_458
FAM81A HAND1 siRNA Placenta HPMVEC 0.525 -0.929611 2.610603e-02 0.9463341 DataSet_03_459
FAM81A TXNIP shRNA Cord_Blood CD34+ cells 7.33333 2.87447 - - DataSet_03_461
FAM81A SOX9 knockout Liver HuH7 0.164384 -2.60486 9.059464e-05 1.976559e-03 DataSet_03_463
FAM81A PARP1 knockout Embryo_kidney HEK293a 2.21582 1.14784 7.945794e-08 1.712115e-06 DataSet_03_464
FAM81A STAT3 shRNA Liver HepG2 1.8088 0.855036 1.421463e-02 0.1817852626 DataSet_03_465
FAM81A SMARCA1 Cas13 Embryo_kidney HEK293T 0.55711 -0.843967 - - DataSet_03_466
FAM81A SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 1.63403 0.708437 - - DataSet_03_467
Regulation Region
 
T(co)Fs that significantly regulate RBM14 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of FAM81A
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines