Gene Overview
| Target Gene: | Fbn2 |
| NCBI Official Symbol: | Fbn2 |
| Entrez ID: | 14119 |
| Ensembl ID: | ENSMUSG00000024598 |
| Gene Full Name: | fibrillin 2 |
| Strand: | - |
| Gene Locus: | 18 D3|18 32.15 cM |
| External Links: |
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Fbn2 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Fbn2
T(co)Fs
that Repress Fbn2
The Intensity of the Gene Regulated by T(co)Fs:
Fbn2-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Fbn2 | Ahr | knockout | Lung | Lung | 1.85888 | 0.894431 | 0.750461845599439 | 0.999996968611848 | DataSet_11_003 |
| Fbn2 | Cbx2 | knockout | Gonads | Embryonic gonads | 1.96766 | 0.976484 | 1.36271337553817e-09 | 1.69245737257707e-07 | DataSet_11_018 |
| Fbn2 | Elf5 | knockout | Mammary_gland | Mammary gland | 1.85123 | 0.888483 | 0.0813902928281584 | 0.357298501652326 | DataSet_11_035 |
| Fbn2 | Gata2 | knockout | Kidney | renal collecting duct cells | 0.492954 | -1.02048 | - | - | DataSet_11_047 |
| Fbn2 | Gfi1 | knockout | Cord_Blood | T-cells | 2.35248 | 1.23418 | 0.209930125900793 | 0.613969448089064 | DataSet_11_053 |
| Fbn2 | Hsf4 | knockout | Eye | Lens | 0.662546 | -0.593908 | 0.638045780983171 | 0.987999303842427 | DataSet_11_058 |
| Fbn2 | Klf17 | shRNA | Mammary_gland | 168FARN | 0.396125 | -1.33597 | 0.00233007470460742 | 0.0182599183113959 | DataSet_11_066 |
| Fbn2 | Lhx8 | knockout | Ovary | Ovary | 1.953 | 0.965691 | 0.00926810378198797 | 0.0501643373022475 | DataSet_11_070 |
| Fbn2 | Mbd1 | siRNA | Adipose_tissue | 3T3-L1 cells | 0.322314 | -1.63346 | - | - | DataSet_11_074 |
| Fbn2 | Mkx | knockout | Tooth | PDL | 2.07485 | 1.053 | 0.557366901298608 | 0.999970897748702 | DataSet_11_083 |
| Fbn2 | Nelfb | knockout | Embryo | Embryonic fibroblasts | 0.500785 | -0.997736 | 1.05699893054174e-05 | 0.000822009468730316 | DataSet_11_086 |
| Fbn2 | Nhlh2 | knockout | Eye | Retina | 0.62098 | -0.687382 | 0.711884306549766 | 0.789145884771889 | DataSet_11_092 |
| Fbn2 | Nrf1 | knockdown | Liver | Liver | 2.35384 | 1.23501 | 0.109535089365576 | 0.207344214718473 | DataSet_11_096 |
| Fbn2 | Pitx2 | knockout | Eye | Cornea | 2.37242 | 1.24636 | 0.0257725203691777 | 0.246656440538453 | DataSet_11_103 |
| Fbn2 | Prox1 | knockout | Liver | Liver | 2.24588 | 1.16728 | - | - | DataSet_11_109 |
| Fbn2 | Rest | shRNA | Brain | NSP | 1.70629 | 0.770863 | 0.299526150103643 | 0.999899167758865 | DataSet_11_111 |
| Fbn2 | Rest | knockout | Brain | Brain | 3.73213 | 1.9 | 0.0804358072938349 | 1 | DataSet_11_113 |
| Fbn2 | Runx1 | knockout | Bone_marrow | KSL cells | 0.627059 | -0.673327 | 0.173265767708877 | 0.927908483380838 | DataSet_11_115 |
| Fbn2 | Runx1 | knockout | Lymph | ProB cells | 0.513249 | -0.96227 | 0.337135969242734 | 0.679047650542524 | DataSet_11_116 |
| Fbn2 | Runx2 | knockout | Humeri | Embryonic humeri | 0.590909 | -0.758992 | 0.15439557045642 | 0.505926698812832 | DataSet_11_120 |
| Fbn2 | Sall4 | shRNA | Embryo | ES cells | 2.36232 | 1.2402 | 0.0937481823779646 | 0.972761027578064 | DataSet_11_123 |
| Fbn2 | Smad4 | siRNA | Brain | bEnd3 | 69.8072 | 6.1253 | - | - | DataSet_11_127 |
| Fbn2 | Smad4 | knockout | Aorta | Aortic arteries | 10.2691 | 3.36023 | 0.00328709901148046 | 0.108788829313585 | DataSet_11_128 |
| Fbn2 | Snai1 | knockout | Embryo | Teratoma | 0.46856 | -1.0937 | - | - | DataSet_11_130 |
| Fbn2 | Sox11 | knockout | Eye | Retina | 1.65139 | 0.723681 | - | - | DataSet_11_137 |
| Fbn2 | Sox17 | siRNA | Embryo | NG4 | 0.409998 | -1.28631 | 0.00409931687911326 | 0.117274388123708 | DataSet_11_139 |
| Fbn2 | Sox2 | siRNA | Embryo | NG4 | 1.7988 | 0.847035 | 0.00280221763424384 | 0.0568459447883902 | DataSet_11_141 |
| Fbn2 | Sox9 | knockout | Lung | Trachea | 0.485601 | -1.04216 | 0.00391099093952531 | 0.084769325148563 | DataSet_11_144 |
| Fbn2 | Wt1 | siRNA | Embryo_kidney | LB-22 | 0.649967 | -0.621562 | 0.00119586525925277 | 0.0200837581717908 | DataSet_11_179 |
| Fbn2 | Dnmt1 | siRNA | Pituitary_gland | AtT-20 | 1.54113 | 0.623986 | 2.014671e-01 | 0.9999923 | DataSet_11_187 |
| Fbn2 | Pogz | knockdown | Liver | fetal liver | 0.567101 | -0.818322 | 1.567825e-01 | 0.4578305 | DataSet_11_188 |
| Fbn2 | Cpeb1 | siRNA | Neuron | Neuro-2a | 2.59061 | 1.37329 | - | - | DataSet_11_189 |
| Fbn2 | Kdm5b | knockout | Heart | left ventricles | 0.305171 | -1.71231 | 0.1002396420 | 0.9999827 | DataSet_11_210 |
| Fbn2 | Dnmt1 | knockout | Embryo | Embryonic fibroblasts | 0.185006 | -2.43436 | 6.049446e-06 | 6.277667e-04 | DataSet_11_192 |
| Fbn2 | Dnmt1 | shRNA | Embryo | Embryonic fibroblasts | 0.644264 | -0.634276 | - | - | DataSet_11_196 |
| Fbn2 | Brca1 | knockout | Brain | mouse P7 brain | 1.92425 | 0.944299 | 2.209849e-03 | 0.18147349 | DataSet_11_201 |
| Fbn2 | Bptf | shRNA | Mammary_gland | 4T1 cells | 0.366868 | -1.44667 | 3.506223e-04 | 0.055119508 | DataSet_11_223 |
| Fbn2 | Ncl | siRNA | Embryo | ES cells | 0.610478 | -0.711988 | 1.883700e-01 | 0.5366378844 | DataSet_11_240 |
| Fbn2 | Dnmt3a | siRNA | Embryo | iPSC | 0.12299 | -3.02339 | - | - | DataSet_11_241 |
| Fbn2 | Lin28a | knockout | Heart | Heart | 0.23649 | -2.08015 | 0.3195630491 | 0.8777652 | DataSet_11_243 |
| Fbn2 | Twist1 | knockout | Bone_marrow | stromal cells | 4.01928e-20 | -64.4316 | - | - | DataSet_11_244 |
| Fbn2 | Kat6a | knockout | Embryo | Embryonic fibroblasts | 0.394886 | -1.34049 | 2.256445e-02 | 0.1760912758 | DataSet_11_245 |
| Fbn2 | Fubp1 | shRNA | Brain | brain neural progenitors | 4.55505 | 2.18747 | 0.2415099570 | 1 | DataSet_11_246 |
| Fbn2 | Kmt2d | knockout | Skin | iBiP melanoma mouse model tumor cell | 13.7188 | 3.77808 | 5.135606e-06 | 2.460872e-04 | DataSet_11_250 |
| Fbn2 | Kdm2a | CRISPR | Embryo | ES cells | 2.192 | 1.13225 | 0.4575095056 | 1.0000000 | DataSet_11_251 |
| Fbn2 | Zbp1 | siRNA | Bone_marrow | bone marrow-derived mesenchymal stem_progenitor cells | 0.177186 | -2.49667 | 1.233647e-02 | 0.065921982 | DataSet_11_252 |
| Fbn2 | Fubp1 | shRNA | Bone_marrow | BM cells | 4 | 2 | 3.135033e-01 | 0.846117121 | DataSet_11_262 |
| Fbn2 | Bcl3 | knockout | Bone | Osteoblast | 1.5563 | 0.63812 | 4.593135e-02 | 6.909331e-01 | DataSet_11_263 |
| Fbn2 | Nr4a1 | knockout | Mammary_gland | PyVT mouse mammary tumor cells | 0.174561 | -2.51819 | 1.523865e-01 | 0.7273107 | DataSet_11_268 |
| Fbn2 | Dux | knockout | Embryo | Embryo | 15.3165 | 3.93701 | 1.293180e-05 | 2.287375e-04 | DataSet_11_269 |
| Fbn2 | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 6.38159 | 2.67392 | 4.865603e-01 | 0.84073142 | DataSet_11_272 |
| Fbn2 | Dux | knockout | Embryo | Embryo | 15.3165 | 3.93701 | 1.293179e-05 | 2.287141e-04 | DataSet_11_273 |
| Fbn2 | Ezh2 | siRNA | Bone_marrow | Mesenchymal stem cells | 0.307692 | -1.70044 | 2.356722e-01 | 5.543026e-01 | DataSet_11_276 |
| Fbn2 | Ssrp1 | CRISPR | Embryo | ES cells | 0.640449 | -0.642843 | 2.607500e-01 | 0.7914316 | DataSet_11_278 |
| Fbn2 | Zmat3 | knockout | Embryo | Embryonic fibroblasts | 2.17956 | 1.12404 | 1.332645e-01 | 0.5395938 | DataSet_11_284 |
| Fbn2 | Usp7 | siRNA | Embryo | ES cells | 2.58974 | 1.37281 | 1.371062e-02 | 0.6667924 | DataSet_11_287 |
| Fbn2 | Irf8 | knockout | Brain | mice brain | 1.80785 | 0.854274 | 2.380326e-01 | 7.747060e-01 | DataSet_11_292 |
| Fbn2 | Phf8 | knockout | prostate | Prostate | 40.9286 | 5.35504 | 0.0329436247 | 0.2242520 | DataSet_11_298 |
| Fbn2 | Brpf1 | shRNA | Nerve | Neural progenitor cells | 0.568217 | -0.815486 | 5.773487e-01 | 0.9999903 | DataSet_11_299 |
| Fbn2 | Arid2 | knockout | Muscle | LSK | 3.5 | 1.80736 | 6.328678e-02 | 7.843001e-01 | DataSet_11_301 |
| Fbn2 | Dnmt1 | knockout | Skin | Keratinocytes | 4.09593 | 2.03419 | 2.418154e-02 | 0.2114580399 | DataSet_11_303 |
| Fbn2 | Jmjd6 | knockout | Bone_marrow | Lin-Sca1+Kit+ (LSK) haematopoietic stem and progenitor cells | 0.642857 | -0.63743 | - | - | DataSet_11_306 |
| Fbn2 | Myc | CRISPR | Skeletal_muscle | quiescent muscle stem cell | 51.6657 | 5.69113 | 3.153224e-01 | 0.80359421 | DataSet_11_310 |
| Fbn2 | Satb2 | knockout | Colon | Intestine epithelium | 0.141177 | -2.82443 | 3.625771e-03 | 0.1107292858 | DataSet_11_316 |
| Fbn2 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.386646 | -1.37092 | 6.087871e-02 | 2.122998e-01 | DataSet_11_320 |
| Fbn2 | Gata2 | knockout | Brain | Pituitary gland | 2.25 | 1.16992 | 0.828189949 | 1.0000000 | DataSet_11_322 |
| Fbn2 | Setdb1 | shRNA | Neuron | NE-4C | 1.58974 | 0.668789 | - | - | DataSet_11_323 |
| Fbn2 | Kdm5b | siRNA | Embryo | ES cells | 0.654402 | -0.611752 | 0.7792534063 | 0.9518283 | DataSet_11_331 |
| Fbn2 | Ezh2 | shRNA | Brain | SVZ derived neural stem cells | 3.05168 | 1.6096 | 6.770569e-05 | 5.133363e-03 | DataSet_11_332 |
| Fbn2 | Ezh2 | knockout | Eye | Retina | 1.50316 | 0.587999 | 0.7658212079 | 1.0000000 | DataSet_11_334 |
| Fbn2 | Dnmt3a | knockout | Peritoneum | peritoneal macrophages | 0.302512 | -1.72494 | - | - | DataSet_11_336 |
| Fbn2 | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 0.465232 | -1.10398 | 5.128847e-03 | 0.015997283 | DataSet_11_340 |
| Fbn2 | Ezh2 | knockout | Small_intestinal_crypts | small intestinal crypts | 0.6 | -0.736966 | 0.6993641644 | 0.7442593 | DataSet_11_341 |
| Fbn2 | Hnrnpk | siRNA | Embryo | ES cells | 0.461677 | -1.11504 | 1.011497e-02 | 0.027602954 | DataSet_11_342 |
Regulation Region
Expression Atlas of Fbn2